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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H12N4O3
Molecular Weight 236.2273
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIDANOSINE

SMILES

OC[C@@H]1CC[C@@H](O1)N2C=NC3=C2N=CNC3=O

InChI

InChIKey=BXZVVICBKDXVGW-NKWVEPMBSA-N
InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

HIDE SMILES / InChI
Molecular Formula C10H12N4O3
Molecular Weight 236.2273
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:35:34 UTC 2023
Edited
by admin
on Fri Dec 15 15:35:34 UTC 2023
Record UNII
K3GDH6OH08
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIDANOSINE
EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   VANDF   WHO-DD   WHO-IP  
INN   USAN  
Official Name English
DIDANOSINE [MI]
Common Name English
(-)-DIDANOSINE
Common Name English
didanosine [INN]
Common Name English
DIDANOSINUM [WHO-IP LATIN]
Common Name English
DIDANOSINE [USP IMPURITY]
Common Name English
DIDANOSINE [EP MONOGRAPH]
Common Name English
NSC-612049
Code English
INOSINE, 2',3'-DIDEOXY-
Systematic Name English
DIDEOXYINOSINE
Systematic Name English
2',3'-DIDEOXYINOSINE
Systematic Name English
DIDANOSINE [WHO-IP]
Common Name English
DIDANOSINE [USAN]
Common Name English
DIDANOSINE [VANDF]
Common Name English
DIDANOSINE [ORANGE BOOK]
Common Name English
DIDANOSINE SYSTEM SUITABILITY MIXTURE
USP-RS  
Common Name English
DIDANOSINE [USP-RS]
Common Name English
DIDANOSINE [JAN]
Common Name English
DIDANOSINE [EP IMPURITY]
Common Name English
DIDANOSINE [MART.]
Common Name English
BMY-40900
Code English
DIDANOSINE SYSTEM SUITABILITY MIXTURE [USP-RS]
Common Name English
DIDANOSINE [USP MONOGRAPH]
Common Name English
DIDANOSINE [HSDB]
Common Name English
Didanosine [WHO-DD]
Common Name English
Classification Tree Code System Code
NDF-RT N0000009947
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
WHO-VATC QJ05AF02
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
NDF-RT N0000175459
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
NCI_THESAURUS C97452
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
WHO-ATC J05AF02
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.4.2.1
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
NDF-RT N0000175459
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
FDA ORPHAN DRUG 29488
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
NDF-RT N0000175462
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
NDF-RT N0000175459
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
LIVERTOX NBK548326
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
Code System Code Type Description
MERCK INDEX
m4379
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY Merck Index
EVMPD
SUB07104MIG
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
HSDB
6548
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
PUBCHEM
135398739
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
EPA CompTox
DTXSID6022927
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
FDA UNII
K3GDH6OH08
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
NCI_THESAURUS
C431
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
WIKIPEDIA
DIDANOSINE
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
RS_ITEM_NUM
1191204
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
INN
6664
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
LACTMED
Didanosine
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
ChEMBL
CHEMBL1460
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
RXCUI
3364
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY RxNorm
DAILYMED
K3GDH6OH08
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
SMS_ID
100000087146
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
CAS
69655-05-6
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
MESH
D016049
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
DRUG CENTRAL
869
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
IUPHAR
4833
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
DIDANOSINE
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY Description: A white to almost white powder.Solubility: Sparingly soluble in water; slightly soluble in methanol R and ethanol (95 per cent) R.Category: Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor).Storage: Didanosine should be kept in a tightly closed container.Requirements: Didanosine contains not less than 98.5% and not more than 101.0% of C10H12N4O3, calculated with reference to the driedsubstance.
NSC
612049
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
USAN
CC-20
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
CHEBI
490877
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
DRUG BANK
DB00900
Created by admin on Fri Dec 15 15:35:34 UTC 2023 , Edited by admin on Fri Dec 15 15:35:34 UTC 2023
PRIMARY
Related Record Type Details
Structure of DIDANOSINE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of DIDANOSINE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 POLYMERASE
TARGET -> INHIBITOR
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
TARGET ORGANISM->INHIBITOR
Related Record Type Details
Structure of 2'-DEOXYINOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3'-DEOXYINOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of INOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2'-DEOXYINOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYPOXANTHINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIDEOXYADENOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIDANOSINE ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2′,3′-Anhydroinosine
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2',3'-DIDEOXY-2',3'-DIDEHYDROINOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3'-DEOXYINOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2′,3′-Anhydroinosine
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 9-(2,5-DI-O-ACETYL-3-BROMO-3-DEOXY-.BETA.-D-XYLOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ONE
IMPURITY -> PARENT
Structure of 2',3'-DIDEOXY-2',3'-DIDEHYDROINOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of DIDEOXYADENOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2',3'-DIDEHYDRO-2',3'-DIDEOXYINOSINE-5'-ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2',3'-O-(1-METHOXYETHYLIDENE)INOSINE
IMPURITY -> PARENT
Structure of INOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE
IMPURITY -> PARENT
In the chromatogram obtained with solution (2), the following peaks are eluted at the following relative retention with reference to didanosine (retention time about 13-15 min): impurity I about 1.4.
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYPOXANTHINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2',3',5'-TRIDEOXYADENOSINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 9-(3,5-DI-O-ACETYL-2-BROMO-2-DEOXY-.BETA.-D-ARABINOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ONE
IMPURITY -> PARENT
Related Record Type Details
Structure of DIDANOSINE
ACTIVE MOIETY
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