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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H32O5
Molecular Weight 352.4651
Optical Activity ( - )
Defined Stereocenters 4 / 4
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of DINOPROSTONE

SMILES

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

InChI

InChIKey=XEYBRNLFEZDVAW-ARSRFYASSA-N
InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1

HIDE SMILES / InChI
Molecular Formula C20H32O5
Molecular Weight 352.4651
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 2
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:12:48 UTC 2023
Edited
by admin
on Fri Dec 15 15:12:48 UTC 2023
Record UNII
K7Q1JQR04M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DINOPROSTONE
EP   INN   JAN   MART.   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
DINOPROSTONE [EP MONOGRAPH]
Common Name English
DINOPROSTONE [USP-RS]
Common Name English
PROSTAGLANDIN E2
MI  
Common Name English
dinoprostone [INN]
Common Name English
NSC-165560
Code English
DINOPROSTONE [ORANGE BOOK]
Common Name English
CERVIDIL
Brand Name English
DINOPROSTONE [USP IMPURITY]
Common Name English
MINPROSTIN E2
Brand Name English
PROSTA-5,13-DIEN-1-OIC ACID, 11,15-DIHYDROXY-9-OXO-, (5Z,11.ALPHA.,13E,15S)-
Systematic Name English
PROSTIN E2
Brand Name English
DINOPROSTONE [USP MONOGRAPH]
Common Name English
PREPIDIL
Brand Name English
U-12,062
Code English
U-12062
Code English
ENZAPROST E
Brand Name English
DINOPROSTONE [VANDF]
Common Name English
Dinoprostone [WHO-DD]
Common Name English
DINOPROSTONE [MART.]
Common Name English
PGE2
Common Name English
PROPESS
Brand Name English
ALPROSTADIL IMPURITY G [EP IMPURITY]
Common Name English
(E,Z)-(1R,2R,3R)-7-[3-Hydroxy-2-[(3S)-(3-hydroxy-1-octenyl)]-5-oxocyclopentyl]-5-heptenoic acid
Systematic Name English
DINOPROSTONE [JAN]
Common Name English
DINOPROSTONE [USAN]
Common Name English
PROSTAGLANDIN E2 [MI]
Common Name English
NSC-196514
Code English
Classification Tree Code System Code
LOINC 12836-3
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
LOINC 70091-4
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
LOINC 2853-0
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
NCI_THESAURUS C78568
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
WHO-ATC G02AD02
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
LOINC 14006-1
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
NCI_THESAURUS C782
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
NDF-RT N0000007706
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
WHO-VATC QG02AD02
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
NDF-RT N0000007706
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
NDF-RT N0000175454
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
NDF-RT N0000007706
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
Code System Code Type Description
EVMPD
SUB07195MIG
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
DAILYMED
K7Q1JQR04M
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
NSC
196514
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
SMS_ID
100000092220
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
EPA CompTox
DTXSID4022947
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
ECHA (EC/EINECS)
206-656-6
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
WIKIPEDIA
PROSTAGLANDIN E2
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
CAS
363-24-6
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
NSC
165560
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
RXCUI
3478
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY RxNorm
FDA UNII
K7Q1JQR04M
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
DRUG CENTRAL
913
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
IUPHAR
1883
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
LACTMED
Dinoprostone
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
CHEBI
606564
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
MESH
D015232
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
ChEMBL
CHEMBL548
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
RS_ITEM_NUM
1213103
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
MERCK INDEX
m9258
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY Merck Index
DRUG BANK
DB00917
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
INN
3075
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
PUBCHEM
5280360
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
CHEBI
15551
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
NCI_THESAURUS
C61727
Created by admin on Fri Dec 15 15:12:48 UTC 2023 , Edited by admin on Fri Dec 15 15:12:48 UTC 2023
PRIMARY
Related Record Type Details
PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE
TARGET -> AGONIST
Structure of DINOPROSTONE H-3
LABELED -> NON-LABELED
Structure of DINOPROSTONE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of CRISDESALAZINE
INHIBITOR -> TARGET
PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE
TARGET -> AGONIST
Ki
PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE
TARGET -> AGONIST
Ki
Tesrivetcel
PARENT -> CONSTITUENT ALWAYS PRESENT
PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE
TARGET -> AGONIST
Latovetcel
PARENT -> CONSTITUENT ALWAYS PRESENT
Structure of DINOPROSTONE TROMETHAMINE
SALT/SOLVATE -> PARENT
Structure of DINOPROSTONE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE
TARGET -> AGONIST
PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE
TARGET -> AGONIST
Ki
PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE
TARGET -> AGONIST
Ki
PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE
TARGET -> AGONIST
Alisvetcel
PARENT -> CONSTITUENT ALWAYS PRESENT
Related Record Type Details
Structure of 15-KETOPROSTAGLANDIN E2
METABOLITE -> PARENT
Related Record Type Details
Structure of PROSTAGLANDIN B2
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 0.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ALPROSTADIL
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-TRANS-PROSTAGLANDIN E2
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of PROSTAGLANDIN A2
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 0.2
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 15-KETOPROSTAGLANDIN E2
IMPURITY -> PARENT
The sum of these three impurities is NMT 1.0%. (15-Oxo-dinoprostone, 15-Epi-dinoprostone,and 8-Isodinoprostone)
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 8-ISOPROSTAGLANDIN E2
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 15-EPI-PROSTAGLANDIN E2
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 5-TRANS-PROSTAGLANDIN E2
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 15-KETOPROSTAGLANDIN E2
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 8-ISOPROSTAGLANDIN E2
IMPURITY -> PARENT
The sum of these three impurities is NMT 1.0%. (15-Oxo-dinoprostone, 15-Epi-dinoprostone,and 8-Isodinoprostone)
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 15-EPI-PROSTAGLANDIN E2
IMPURITY -> PARENT
The sum of these three impurities is NMT 1.0%. (15-Oxo-dinoprostone, 15-Epi-dinoprostone,and 8-Isodinoprostone)
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of PROSTAGLANDIN A2
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of PROSTAGLANDIN B2
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of DINOPROSTONE
ACTIVE MOIETY
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