ANAGRELIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H7Cl2N3O
Molecular Weight	256.088
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ANAGRELIDE

Structure Search

SMILES

ClC1=CC=C2NC3=NC(=O)CN3CC2=C1Cl

InChI

InChIKey=OTBXOEAOVRKTNQ-UHFFFAOYSA-N

InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16)

HIDE SMILES / InChI

Molecular Formula	C10H7Cl2N3O
Molecular Weight	256.088
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:51:16 UTC 2023` Edited by `admin` on `Fri Dec 15 15:51:16 UTC 2023`
Record UNII	K9X45X0051
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ANAGRELIDE

Official Name

English

ANAGRELIDE [HSDB]

Common Name

English

Anagrelide [WHO-DD]

Common Name

English

anagrelide [INN]

Common Name

English

ANAGRELIDE [EMA EPAR]

Common Name

English

6,7-DICHLORO-1,5-DIHYDROIMIDAZO(2,1-B)-QUINAZOLIN-2(3H)-ONE MONOHYDROCHLORIDE

Systematic Name

English

ANAGRELIDE [VANDF]

Common Name

English

IMIDAZO(2,1-B)QUINAZOLIN-2(3H)-ONE, 6,7-DICHLORO-1,5-DIHYDRO-, MONOHYDROCHLORIDE

Common Name

English

ANAGRELIDE [MI]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

935223

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

LIVERTOX

NBK548467

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

FDA ORPHAN DRUG

14586

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

NDF-RT

N0000175972

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

FDA ORPHAN DRUG

20887

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

FDA ORPHAN DRUG

6985

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

WHO-VATC

QL01XX35

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

NCI_THESAURUS

C1327

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

NDF-RT

N0000175638

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

WHO-ATC

L01XX35

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID4048305

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

CHEBI

142290

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

NCI_THESAURUS

C28825

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

DRUG CENTRAL

209

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

EVMPD

SUB05499MIG

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

CAS

68475-42-3

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

MERCK INDEX

m1886

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

Merck Index

IUPHAR

7114

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

ChEMBL

CHEMBL760

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

FDA UNII

K9X45X0051

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

CHEBI

55345

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

WIKIPEDIA

ANAGRELIDE

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

SMS_ID

100000085241

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

PUBCHEM

135409400

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

LACTMED

Anagrelide

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

RXCUI

596724

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

RxNorm

DAILYMED

K9X45X0051

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

HSDB

7325

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

DRUG BANK

DB00261

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

INN

4672

Created by admin on Fri Dec 15 15:51:16 UTC 2023 , Edited by admin on Fri Dec 15 15:51:16 UTC 2023

PRIMARY

Related Record Type Details


					VK4SQL11C0

CYTOCHROME P450 1A2

METABOLIC ENZYME -> SUBSTRATE


					JOC85XIO65

CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A

OFF-TARGET->INHIBITOR

Qualification:

IC50

Amount:


					YTM763Y5C8

ANAGRELIDE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					K9X45X0051

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					VNS4435G39

ANAGRELIDE HYDROCHLORIDE ANHYDROUS

SALT/SOLVATE -> PARENT

Related Record Type Details


					BD898EX8IE

RL-603

METABOLITE INACTIVE -> PARENT


					PIN0NPZ24B

3-HYDROXY ANAGRELIDE

METABOLITE ACTIVE -> PARENT

Amount:

Related Record Type Details


					K9X45X0051

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC