PRAVASTATIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C23H36O7
Molecular Weight	424.5277
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRAVASTATIN

Structure Search

SMILES

[H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)OC(=O)[C@@H](C)CC

InChI

InChIKey=TUZYXOIXSAXUGO-PZAWKZKUSA-N

InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C23H36O7
Molecular Weight	424.5277
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:54:46 UTC 2023` Edited by `admin` on `Sat Dec 16 16:54:46 UTC 2023`
Record UNII	KXO2KT9N0G
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PRAVASTATIN

Official Name

English

PRAVASTATIN [EMA EPAR]

Common Name

English

Pravastatin [WHO-DD]

Common Name

English

C10AA03

Code

English

pravastatin [INN]

Common Name

English

PRAVASTATIN [VANDF]

Common Name

English

PRAVATOR

Brand Name

English

Classification Tree Code System Code

WHO-VATC

QC10BX02

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

NDF-RT

N0000175589

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

WHO-VATC

QC10BA03

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

WHO-VATC

QC10AA03

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

WHO-ATC

C10BA03

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

LIVERTOX

NBK548653

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

WHO-ATC

C10BX02

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

WHO-ATC

C10AA03

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

NDF-RT

N0000000121

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

NCI_THESAURUS

C1655

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

EU-Orphan Drug

EU/3/10/748

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

Code System Code Type Description

DRUG CENTRAL

2239

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

PUBCHEM

54687

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

FDA UNII

KXO2KT9N0G

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

CAS

81093-37-0

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

IUPHAR

2953

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

DRUG BANK

DB00175

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

WIKIPEDIA

PRAVASTATIN

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

MESH

D017035

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

SMS_ID

100000091161

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

EVMPD

SUB10004MIG

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

EPA CompTox

DTXSID6023498

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

INN

6070

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

ChEMBL

CHEMBL1144

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

DAILYMED

KXO2KT9N0G

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

LACTMED

Pravastatin

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

CHEBI

63660

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

RXCUI

42463

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

RxNorm

NCI_THESAURUS

C62070

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

CHEBI

63618

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

HSDB

8368

Created by admin on Sat Dec 16 16:54:48 UTC 2023 , Edited by admin on Sat Dec 16 16:54:48 UTC 2023

PRIMARY

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3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE

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BSEP

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					66DDF797LP

OATP-8

TRANSPORTER -> SUBSTRATE


					AIN96D6SGL

OATP1B1

TRANSPORTER -> SUBSTRATE


					3M8608UQ61

PRAVASTATIN SODIUM

SALT/SOLVATE -> PARENT


					ZWJ2Y6JZWY

OAT-3

TRANSPORTER -> INHIBITOR


					G49RZO51ZC

OATP-B

TRANSPORTER -> SUBSTRATE


					T17047131H

PRAVASTATIN 1,1,3,3-TETRAMETHYLBUTYLAMINE

SALT/SOLVATE -> PARENT

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3'.ALPHA.-ISOPRAVASTATIN

METABOLITE LESS ACTIVE -> PARENT


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3''-HYDROXYPRAVASTATIN

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR


					774J05US3V

SQ-31945

METABOLITE LESS ACTIVE -> PARENT

Interaction Type:

MAJOR


					4411KHU5T3

DESACYL-DEHYDROPRAVASTATIN

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR


					SHW904Q14D

3'.ALPHA.-ISOPRAVASTATIN

PARENT -> METABOLITE LESS ACTIVE

Interaction Type:

MAJOR


					R76ZW7E32P

6'-EPIPRAVASTATIN

PARENT -> METABOLITE INACTIVE

Interaction Type:

MAJOR

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ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
PROTEIN BINDING	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC

ORAL BIOAVAILABILITY	PHARMACOKINETIC

Route of Elimination	PHARMACOKINETIC				RENAL PHARMACOKINETIC

Tmax	PHARMACOKINETIC