CRENOLANIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H29N5O2
Molecular Weight	443.5408
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CRENOLANIB

Structure Search

SMILES

CC6(COC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(N)CC5)C=C3)COC6

InChI

InChIKey=DYNHJHQFHQTFTP-UHFFFAOYSA-N

InChI=1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3

HIDE SMILES / InChI

Molecular Formula	C26H29N5O2
Molecular Weight	443.5408
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 20:15:00 UTC 2023` Edited by `admin` on `Fri Dec 15 20:15:00 UTC 2023`
Record UNII	LQF7I567TQ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CRENOLANIB

Official Name

English

CP-868,596

Code

English

CRENOLANIB [USAN]

Common Name

English

CP-868

Code

English

ARO-002

Code

English

ARO 002

Code

English

CP-868596

Code

English

1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine

Systematic Name

English

Crenolanib [WHO-DD]

Common Name

English

4-PIPERIDINAMINE, 1-(2-(5-((3-METHYL-3-OXETANYL)METHOXY)-1H-BENZIMIDAZOL-1-YL)-8-QUINOLINYL)-

Systematic Name

English

CP 868596

Code

English

crenolanib [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

706819

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

NCI_THESAURUS

C1967

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

FDA ORPHAN DRUG

363812

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

FDA ORPHAN DRUG

335911

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

Code System Code Type Description

DRUG BANK

DB11832

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

USAN

XX-154

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

WIKIPEDIA

CRENOLANIB

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

NCI_THESAURUS

C64639

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

SMS_ID

100000170917

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

FDA UNII

LQF7I567TQ

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

CHEBI

145365

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

EPA CompTox

DTXSID50985873

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

ChEMBL

CHEMBL2105728

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

INN

9459

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

CAS

670220-88-9

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

PUBCHEM

10366136

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

EVMPD

SUB185102

Created by admin on Fri Dec 15 20:15:00 UTC 2023 , Edited by admin on Fri Dec 15 20:15:00 UTC 2023

PRIMARY

Related Record Type Details


					MC4B01024K

CRENOLANIB BESYLATE

SALT/SOLVATE -> PARENT


					OVI08ABI5H

MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT

TARGET -> INHIBITOR

Interaction Type:

INHIBITOR

Related Record Type Details


					LQF7I567TQ

ACTIVE MOIETY