AMIFOSTINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H15N2O3PS.3H2O
Molecular Weight	268.269
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AMIFOSTINE

Structure Search

SMILES

O.O.O.NCCCNCCSP(O)(O)=O

InChI

InChIKey=TXQPXJKRNHJWAX-UHFFFAOYSA-N

InChI=1S/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C5H15N2O3PS
Molecular Weight	214.223
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:20:29 UTC 2023` Edited by `admin` on `Fri Dec 15 16:20:29 UTC 2023`
Record UNII	M487QF2F4V
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AMIFOSTINE

Official Name

English

AMIFOSTINE [MART.]

Common Name

English

AMIFOSTINE [USP MONOGRAPH]

Common Name

English

GAMMAPHOS

Common Name

English

Amifostine trihydrate [WHO-DD]

Common Name

English

AMIFOSTINE [USP-RS]

Common Name

English

WR-2721 TRIHYDRATE

Code

English

AMIFOSTINE [USAN]

Common Name

English

S-[2-[(3-Aminopropyl)amino]ethyl] dihydrogen phosphorothioate, trihydrate

Systematic Name

English

NSC-296961

Code

English

AMIFOSTINE [VANDF]

Common Name

English

AMIFOSTINE TRIHYDRATE [MI]

Common Name

English

ETHYOL

Brand Name

English

AMIFOSTINE TRIHYDRATE

Common Name

English

ETHIOFOS

Common Name

English

ETHANETHIOL, 2-((3-AMINOPROPYL)AMINO)-, DIHYDROGEN PHOSPHATE (ESTER), TRIHYDRATE

Common Name

English

AMIFOSTINE [ORANGE BOOK]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

128399

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

FDA ORPHAN DRUG

116298

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

WHO-VATC

QV03AF05

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

FDA ORPHAN DRUG

24187

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

FDA ORPHAN DRUG

42989

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

FDA ORPHAN DRUG

111698

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

NDF-RT

N0000180854

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

FDA ORPHAN DRUG

42789

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

NCI_THESAURUS

C2080

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

FDA ORPHAN DRUG

42889

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

LIVERTOX

36

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

WHO-ATC

V03AF05

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

Code System Code Type Description

MESH

D004999

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

USAN

DD-7

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

DRUG BANK

DB01143

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

RXCUI

4126

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

RxNorm

DAILYMED

M487QF2F4V

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

WIKIPEDIA

AMIFOSTINE

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

RS_ITEM_NUM

1019406

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

MERCK INDEX

m1669

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

Merck Index

SMS_ID

100000091456

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

NCI_THESAURUS

C488

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

EPA CompTox

DTXSID40150210

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

EVMPD

SUB27016

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

CHEBI

2636

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

FDA UNII

M487QF2F4V

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

ChEMBL

CHEMBL1006

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

CAS

112901-68-5

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

NSC

296961

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

DRUG CENTRAL

156

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

PUBCHEM

148139

Created by admin on Fri Dec 15 16:20:29 UTC 2023 , Edited by admin on Fri Dec 15 16:20:29 UTC 2023

PRIMARY

Related Record Type Details


					ILA426L95O

AMIFOSTINE ANHYDROUS

ANHYDROUS->SOLVATE


					ILA426L95O

AMIFOSTINE ANHYDROUS

PARENT -> SALT/SOLVATE

Amount:


					M487QF2F4V

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:

Related Record Type Details


					05P3K9I49L

N-(2-MERCAPTOETHYL)-1,3-DIAMINOPROPANE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					S8KC806H2T

Bis[2-(3-aminopropylamino)ethyl]disulfide

IMPURITY -> PARENT

Amount:

Related Record Type Details


					ILA426L95O

AMIFOSTINE ANHYDROUS

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC