MASITINIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H30N6OS
Molecular Weight	498.642
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MASITINIB

Structure Search

SMILES

CN1CCN(CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(NC4=NC(=CS4)C5=CN=CC=C5)=C3)CC1

InChI

InChIKey=WJEOLQLKVOPQFV-UHFFFAOYSA-N

InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)

HIDE SMILES / InChI

Molecular Formula	C28H30N6OS
Molecular Weight	498.642
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:06:17 UTC 2023` Edited by `admin` on `Fri Dec 15 16:06:17 UTC 2023`
Record UNII	M59NC4E26P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MASITINIB

Official Name

English

4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE

Systematic Name

English

MASITINIB [MI]

Common Name

English

masitinib [INN]

Common Name

English

MASITINIB [MART.]

Common Name

English

Masitinib [WHO-DD]

Common Name

English

KINAVET

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1967

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

EU-Orphan Drug

EU/3/04/251

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

WHO-VATC

QL01XE22

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

FDA ORPHAN DRUG

285309

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

FDA ORPHAN DRUG

210505

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

EMA ASSESSMENT REPORTS

MASIVIERA (REFUSED: PANCREATIC NEOPLASMS)

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

EU-Orphan Drug

EU/3/05/286

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

FDA ORPHAN DRUG

201005

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

EMA ASSESSMENT REPORTS

MASICAN (REFUSED: GASTROINTESTINAL STROMAL TUMORS)

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

FDA ORPHAN DRUG

201505

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

EU-Orphan Drug

EU/3/04/251

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

EU-Orphan Drug

EU/3/04/242

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

Code System Code Type Description

EU-Orphan Drug

EU/3/04/251(POSITIVE)

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

TREATMENT OF MALIGNANT GASTROINTESTINAL STROMAL TUMOURS 20/12/2004 POSITIVE

CHEBI

63450

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

EPA CompTox

DTXSID001000207

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

SMS_ID

100000124415

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

CAS

790299-79-5

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

NCI_THESAURUS

C79910

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

WIKIPEDIA

Masitinib

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

ChEMBL

CHEMBL1908391

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

PUBCHEM

10074640

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

DRUG BANK

DB11526

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

MESH

C526575

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

FDA UNII

M59NC4E26P

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

INN

8779

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

MERCK INDEX

m7092

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

Merck Index

EVMPD

SUB32266

Created by admin on Fri Dec 15 16:06:17 UTC 2023 , Edited by admin on Fri Dec 15 16:06:17 UTC 2023

PRIMARY

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Interaction Type:

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MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR

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PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA

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MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 7

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Amount:


					S5HU9GN0P9

TYROSINE-PROTEIN KINASE FYN

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					ZK89EG3A18

MASITINIB MESYLATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					M59NC4E26P

MASITINIB

ACTIVE MOIETY