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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H20FNO3.CH4O3S
Molecular Weight 425.471
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PAROXETINE MESYLATE

SMILES

CS(O)(=O)=O.FC1=CC=C(C=C1)[C@@H]2CCNC[C@H]2COC3=CC=C4OCOC4=C3

InChI

InChIKey=SHIJTGJXUHTGGZ-RVXRQPKJSA-N
InChI=1S/C19H20FNO3.CH4O3S/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;1-5(2,3)4/h1-6,9,14,17,21H,7-8,10-12H2;1H3,(H,2,3,4)/t14-,17-;/m0./s1

HIDE SMILES / InChI
Molecular Formula CH4O3S
Molecular Weight 96.106
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C19H20FNO3
Molecular Weight 329.3654
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:35:10 UTC 2023
Edited
by admin
on Fri Dec 15 16:35:10 UTC 2023
Record UNII
M711N184JE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PAROXETINE MESYLATE
ORANGE BOOK   USAN  
USAN  
Official Name English
PIPERIDINE, 3-((1,3-BENZODIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)-, (3S,4R)-, METHANESULFONATE (1:1)
Systematic Name English
Paroxetine mesilate [WHO-DD]
Common Name English
POT.MES
Code English
MESAFEM
Brand Name English
PAROXETINE MESYLATE [USAN]
Common Name English
PIPERIDINE, 3-((1,3-BENZODIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)-, (3S,4R)-, METHANESULPHONATE
Systematic Name English
PO-T.MES
Code English
(-)-TRANS-4R-(4'-FLUOROPHENYL)-3S-((3',4'-METHYLENEDIOXYPHENOXY)METHYL)PIPERIDINE, MESYLATE
Common Name English
BRISDELLE
Brand Name English
PAROXETINE METHANESULFONATE [MI]
Common Name English
PAROXETINE MESILATE [MART.]
Common Name English
PAROXETINE MESYLATE [ORANGE BOOK]
Common Name English
PIPERIDINE, 3-((1,3-BENZODIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)-, (3S,4R)-, METHANESULFONATE
Systematic Name English
PEXEVA
Brand Name English
PAROXETINE METHANESULPHONATE
Common Name English
(-)-TRANS-4R-(4'-FLUOROPHENYL)-3S-((3',4'-METHYLENEDIOXYPHENOXY)METHYL)PIPERIDINE, MESILATE
Common Name English
PAROXETINE MESILATE
MART.   WHO-DD  
Common Name English
PAROXETINE METHANESULFONATE
MI  
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
NCI_THESAURUS C94725
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID10944385
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
USAN
PP-69
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
FDA UNII
M711N184JE
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
CAS
217797-14-3
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
DAILYMED
M711N184JE
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
PUBCHEM
9845306
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
SMS_ID
100000091353
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
EVMPD
SUB21744
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
MERCK INDEX
m8418
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY Merck Index
RXCUI
436212
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY RxNorm
DRUG BANK
DBSALT000133
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
NCI_THESAURUS
C47653
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
ChEMBL
CHEMBL490
Created by admin on Fri Dec 15 16:35:10 UTC 2023 , Edited by admin on Fri Dec 15 16:35:10 UTC 2023
PRIMARY
Related Record Type Details
Structure of PAROXETINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of PAROXETINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Tmax PHARMACOKINETIC EFFECT OF FOOD

Biological Half-life PHARMACOKINETIC
PROTEIN BINDING PHARMACOKINETIC
Route of Elimination PHARMACOKINETIC EXCRETED UNCHANGED

MAXIMUM TOLERATED DOSE TOXICITY PANIC DISORDER: 60 mg/day

OBSESSIVE-COMPULSIVE DISORDER: 60 mg/day (FDA DOSAGE)

OBSESSIVE-COMPULSIVE DISORDER: 60 TO 100 mg/day (RAPID METABOLIZERS OR THOSE WITH INADEQUATE RESPONSE AFTER 8 WEEKS)

Route of Elimination PHARMACOKINETIC EXCRETED UNCHANGED

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