U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C8H12N4O5
Molecular Weight 244.2047
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AZACITIDINE

SMILES

NC1=NC(=O)N(C=N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

InChI

InChIKey=NMUSYJAQQFHJEW-KVTDHHQDSA-N
InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1

HIDE SMILES / InChI
Molecular Formula C8H12N4O5
Molecular Weight 244.2047
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:11:30 UTC 2023
Edited
by admin
on Sat Dec 16 05:11:30 UTC 2023
Record UNII
M801H13NRU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AZACITIDINE
EMA EPAR   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
AZACITIDINE [ORANGE BOOK]
Common Name English
Azacitidine [WHO-DD]
Common Name English
5-AZACYTIDINE
Systematic Name English
AZACITIDINE [VANDF]
Common Name English
ONUREG
Brand Name English
azacitidine [INN]
Common Name English
AZACITIDINE [MI]
Common Name English
AZACITIDINE [HSDB]
Common Name English
AZACITIDINE [JAN]
Common Name English
VIDAZA
Brand Name English
AZACITIDINE [IARC]
Common Name English
5-AZACITIDINE
Common Name English
4-AMINO-1-.BETA.-D-RIBOFURANOSYL-S-TRIAZIN-2(1H)-ONE
Common Name English
U-18,496
Code English
1,3,5-TRIAZIN-2(1H)-ONE, 4-AMINO-1-.BETA.-D-RIBOFURANOSYL-
Common Name English
AZACYTIDINE
Systematic Name English
AZACITIDINE [EMA EPAR]
Common Name English
AZACITIDINE [MART.]
Common Name English
NSC-102816
Code English
AZACITIDINE [USP-RS]
Common Name English
U-18496
Code English
AZACITIDINE [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 150101
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
WHO-ATC L01BC07
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
FDA ORPHAN DRUG 257008
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
NDF-RT N0000000233
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
EMA ASSESSMENT REPORTS VIDAZA (AUTHORIZED: MYELODYPLASTIC SYNDROMES)
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
LIVERTOX NBK548363
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
WHO-VATC QL01BC07
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
NCI_THESAURUS C2083
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
NDF-RT N0000175595
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
NCI_THESAURUS C1557
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
FDA ORPHAN DRUG 829021
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
EU-Orphan Drug EU/3/01/084
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
Code System Code Type Description
ChEMBL
CHEMBL1489
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
ECHA (EC/EINECS)
206-280-2
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
SMS_ID
100000086905
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
IUPHAR
6796
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
EPA CompTox
DTXSID9020116
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
RS_ITEM_NUM
1045520
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
CHEBI
2038
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
RXCUI
1251
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY RxNorm
WIKIPEDIA
AZACITIDINE
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
DAILYMED
M801H13NRU
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
HSDB
6879
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
NSC
102816
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
PUBCHEM
9444
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
INN
4520
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
MESH
D001374
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
EVMPD
SUB05624MIG
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
MERCK INDEX
m2154
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY Merck Index
LACTMED
Azacitidine
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
FDA UNII
M801H13NRU
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
NCI_THESAURUS
C288
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
DRUG CENTRAL
25
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
CAS
320-67-2
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
DRUG BANK
DB00928
Created by admin on Sat Dec 16 05:11:30 UTC 2023 , Edited by admin on Sat Dec 16 05:11:30 UTC 2023
PRIMARY
Related Record Type Details
DNA (CYTOSINE-5)-METHYLTRANSFERASE 1
TARGET -> INHIBITOR
Related Record Type Details
Structure of N-(Formyl amidino)-N-β-D-ribofuranosylurea
IMPURITY -> PARENT
Structure of 5-AZACYTOSINE
IMPURITY -> PARENT
Related Record Type Details
Structure of AZACITIDINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Tmax PHARMACOKINETIC SUBCUTANEOUS ADMINISTRATION

Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966