TIPIFARNIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H22Cl2N4O
Molecular Weight	489.396
Optical Activity	( + )
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TIPIFARNIB

Structure Search

SMILES

CN1C=NC=C1[C@@](N)(C2=CC=C(Cl)C=C2)C3=CC=C4N(C)C(=O)C=C(C5=CC(Cl)=CC=C5)C4=C3

InChI

InChIKey=PLHJCIYEEKOWNM-HHHXNRCGSA-N

InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C27H22Cl2N4O
Molecular Weight	489.396
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:47:35 UTC 2023` Edited by `admin` on `Fri Dec 15 15:47:35 UTC 2023`
Record UNII	MAT637500A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIPIFARNIB

Official Name

English

2 (1H))-QUINOLINONE,6-(AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-4-(3-CHLOROPHENYL)-1-METHYL-,(+)-

Common Name

English

TIPIFARNIB [MI]

Common Name

English

(R)-6-[Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone

Systematic Name

English

NSC-702818

Code

English

ZARNESTRA

Brand Name

English

TIPIFARNIB [MART.]

Common Name

English

tipifarnib [INN]

Common Name

English

R115777

Code

English

Tipifarnib [WHO-DD]

Common Name

English

R-115777

Code

English

R-11577

Code

English

TIPIFARNIB [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2020

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

EU-Orphan Drug

EU/3/05/269

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

FDA ORPHAN DRUG

730720

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

FDA ORPHAN DRUG

187104

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

FDA ORPHAN DRUG

585317

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

Code System Code Type Description

MESH

C402769

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

CAS

192185-68-5

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

NON-SPECIFIC STEREOCHEMISTRY

SMS_ID

100000085422

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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MERCK INDEX

m10884

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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Merck Index

USAN

NN-43

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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INN

8066

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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PUBCHEM

159324

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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FDA UNII

MAT637500A

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

CHEBI

141969

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

NSC

702818

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

EVMPD

SUB22236

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

ChEMBL

CHEMBL289228

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

DRUG BANK

DB04960

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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CAS

192185-72-1

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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WIKIPEDIA

TIPIFARNIB

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

EPA CompTox

DTXSID5041140

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

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NCI_THESAURUS

C1703

Created by admin on Fri Dec 15 15:47:35 UTC 2023 , Edited by admin on Fri Dec 15 15:47:35 UTC 2023

PRIMARY

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