DERAZANTINIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C29H29FN4O
Molecular Weight	468.5652
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DERAZANTINIB

Structure Search

SMILES

COCCNCCC1=CC(NC2=NC=C3C[C@@H](C4=CC=CC=C4F)C5=CC=CC=C5C3=N2)=CC=C1

InChI

InChIKey=KPJDVVCDVBFRMU-AREMUKBSSA-N

InChI=1S/C29H29FN4O/c1-35-16-15-31-14-13-20-7-6-8-22(17-20)33-29-32-19-21-18-26(24-10-4-5-12-27(24)30)23-9-2-3-11-25(23)28(21)34-29/h2-12,17,19,26,31H,13-16,18H2,1H3,(H,32,33,34)/t26-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C29H29FN4O
Molecular Weight	468.5652
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 20:37:45 UTC 2023` Edited by `admin` on `Fri Dec 15 20:37:45 UTC 2023`
Record UNII	N9B0H171MJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DERAZANTINIB

Official Name

English

Derazantinib [WHO-DD]

Common Name

English

ARQ 087

Code

English

DERAZANTINIB [USAN]

Common Name

English

ARQ087

Code

English

derazantinib [INN]

Common Name

English

BENZO(H)QUINAZOLIN-2-AMINE, 6-(2-FLUOROPHENYL)-5,6-DIHYDRO-N-(3-(2-((2-METHOXYETHYL)AMINO)ETHYL)PHENYL)-, (6R)-

Systematic Name

English

ARQ-087

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1967

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

NCI_THESAURUS

C129825

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL3545421

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

CAS

1814961-15-3

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

NO STRUCTURE GIVEN

NCI_THESAURUS

C104267

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

INN

10488

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

PUBCHEM

46834118

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

SMS_ID

100000181486

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

USAN

FG-224

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

CAS

1234356-69-4

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

DRUG BANK

DB14889

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

FDA UNII

N9B0H171MJ

Created by admin on Fri Dec 15 20:37:45 UTC 2023 , Edited by admin on Fri Dec 15 20:37:45 UTC 2023

PRIMARY

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FIBROBLAST GROWTH FACTOR RECEPTOR 2

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FIBROBLAST GROWTH FACTOR RECEPTOR 3

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Amount:

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ACTIVE MOIETY