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Details

Stereochemistry RACEMIC
Molecular Formula C18H19N3O.ClH.2H2O
Molecular Weight 365.854
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ONDANSETRON HYDROCHLORIDE

SMILES

O.O.Cl.CN1C2=C(C3=C1C=CC=C3)C(=O)C(CN4C=CN=C4C)CC2

InChI

InChIKey=VRSLTNZJOUZKLX-UHFFFAOYSA-N
InChI=1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

HIDE SMILES / InChI
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C18H19N3O
Molecular Weight 293.363
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:44:43 UTC 2023
Edited
by admin
on Fri Dec 15 18:44:43 UTC 2023
Record UNII
NMH84OZK2B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ONDANSETRON HYDROCHLORIDE
MART.   ORANGE BOOK   USAN   USP   USP-RS   VANDF  
USAN  
Official Name English
ONDANSETRON HYDROCHLORIDE DIHYDRATE [MI]
Common Name English
ONDANSETRON HCL
Common Name English
GR 38032F
Code English
ZOPHREN
Brand Name English
ONDANSETRON HYDROCHLORIDE [USP-RS]
Common Name English
4H-CARBAZOL-4-ONE, 1,2,3,9-TETRAHYDRO-9-METHYL-3-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)-, MONOHYDROCHLORIDE, (±)-, DIHYDRATE
Common Name English
ONDANSETRON HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
ZOFRAN
Brand Name English
(±)-2,3-DIHYDRO-9-METHYL-3-((2-METHYLIMIDAZOL-1-YL)METHYL)CARBAZOL-4(1H)-ONE MONOHYDROCHLORIDE DIHYDRATE
Systematic Name English
SN-307
Code English
Ondansetron hydrochloride dihydrate [WHO-DD]
Common Name English
ONDANSETRON MONOHYDROCHLORIDE
Common Name English
GR-C507/75
Code English
GR-38032F
Code English
ONDANSETRON HYDROCHLORIDE HYDRATE
JAN  
Common Name English
ONDANSETRON HYDROCHLORIDE DIHYDRATE
MI   WHO-DD  
Common Name English
4H-CARBAZOL-4-ONE, 1,2,3,9-TETRAHYDRO-9-METHYL-3-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)-, HYDROCHLORIDE, HYDRATE (1:1:2)
Systematic Name English
ONDANSETRON HYDROCHLORIDE HYDRATE [JAN]
Common Name English
ONDANSETRON HYDROCHLORIDE [VANDF]
Common Name English
ONDANSETRON HYDROCHLORIDE DIHYDRATE [EP MONOGRAPH]
Common Name English
SN 307
Code English
ONDANSETRON HYDROCHLORIDE [USAN]
Common Name English
ONDANSETRON (AS HYDROCHLORIDE)
Common Name English
ONDANSETRON HYDROCHLORIDE [ORANGE BOOK]
Common Name English
ONDANSETRON HYDROCHLORIDE [MART.]
Common Name English
ODANSETRON HYDROCHLORIDE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C267
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
NCI_THESAURUS C94726
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
Code System Code Type Description
RXCUI
203148
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY RxNorm
EVMPD
SUB46120
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
SMS_ID
100000131708
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
USAN
Y-91
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
FDA UNII
NMH84OZK2B
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
ChEMBL
CHEMBL46
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
NCI_THESAURUS
C48007
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
MERCK INDEX
m8213
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY Merck Index
RS_ITEM_NUM
1478582
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
PUBCHEM
59774
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
DRUG BANK
DBSALT000921
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
DAILYMED
NMH84OZK2B
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
EVMPD
SUB03517MIG
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
CAS
103639-04-9
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
EPA CompTox
DTXSID9048857
Created by admin on Fri Dec 15 18:44:43 UTC 2023 , Edited by admin on Fri Dec 15 18:44:43 UTC 2023
PRIMARY
Related Record Type Details
Structure of ONDANSETRON HYDROCHLORIDE ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of ONDANSETRON HYDROCHLORIDE ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ONDANSETRON HYDROCHLORIDE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of ONDANSETRON
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of 1,2,3,9-TETRAHYDRO-9-METHYL-3-METHYLENE-4H-CARBAZOL-4-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-METHYLIMIDAZOLE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3((DIMETHYLAMINO)METHYL)-1,2,3,9-TETRAHYDRO-9-METHYL-4H-CARBAZOL-4-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of C-DESMETHYLONDANSETRON
IMPURITY -> PARENT
sum of impurities A and G: not more than the area of the principal peak in the chromatogram obtained with reference solution (a) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3((DIMETHYLAMINO)METHYL)-1,2,3,9-TETRAHYDRO-9-METHYL-4H-CARBAZOL-4-ONE
IMPURITY -> PARENT
sum of impurities A and G: not more than the area of the principal peak in the chromatogram obtained with reference solution (a) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of IMIDAZOLE
IMPURITY -> PARENT
sum of impurities E and F: not more than the sum of the areas of the corresponding peaks in the chromatogram obtained with reference solution (g) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 1,2,3,9-TETRAHYDRO-9-METHYL-3-METHYLENE-4H-CARBAZOL-4-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of IMIDAZOLE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 9-METHYL-1,2,3,9-TETRAHYDRO-4H-CARBAZOL-4-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of N-DESMETHYLONDANSETRON
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 2-METHYLIMIDAZOLE
IMPURITY -> PARENT
sum of impurities E and F: not more than the sum of the areas of the corresponding peaks in the chromatogram obtained with reference solution (g) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 9-METHYL-1,2,3,9-TETRAHYDRO-4H-CARBAZOL-4-ONE
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 0.6
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 6,6'-METHYLENEBIS((3RS)-9-METHYL-3-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)-1,2,3,9-TETRAHYDRO-4H-CARBAZOL-4-ONE)
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
EP
Related Record Type Details
Structure of ONDANSETRON
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