CLOMIPRAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H23ClN2
Molecular Weight	314.852
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CLOMIPRAMINE

Structure Search

SMILES

CN(C)CCCN1C2=CC(Cl)=CC=C2CCC3=C1C=CC=C3

InChI

InChIKey=GDLIGKIOYRNHDA-UHFFFAOYSA-N

InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H23ClN2
Molecular Weight	314.852
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:59:46 UTC 2023` Edited by `admin` on `Fri Dec 15 14:59:46 UTC 2023`
Record UNII	NUV44L116D
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLOMIPRAMINE

Official Name

English

Clomipramine [WHO-DD]

Common Name

English

NSC-169865

Code

English

CHLORIMIPRAMINE

Common Name

English

CLOMIPRAMINE [MI]

Common Name

English

ANAPRAMINE

Common Name

English

clomipramine [INN]

Common Name

English

3-CHLORO-5-(3-(DIMETHYLAMINO)PROPYL)-10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPINE

Systematic Name

English

5H-DIBENZ(B,F)AZEPINE-5-PROPANAMINE, 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-

Systematic Name

English

CLOMICALM

Brand Name

English

3-CHLORO-IMINODIBENZYL

Common Name

English

CLOMIPRAMINE [HSDB]

Common Name

English

CLOMIPRAMINE [VANDF]

Common Name

English

CLOMIPRAMINE [EMA EPAR VETERINARY]

Common Name

English

Classification Tree Code System Code

WHO-ESSENTIAL MEDICINES LIST

24.4

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

NDF-RT

N0000175752

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

WHO-ATC

N06AA04

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

CFR

21 CFR 520.455

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

NCI_THESAURUS

C94727

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

EMA VETERINARY ASSESSMENT REPORTS

CLOMICALM (AUTHORISED)

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

WHO-VATC

QN06AA04

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

LIVERTOX

NBK548878

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C61608

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

RXCUI

2597

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

RxNorm

EPA CompTox

DTXSID6022844

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

CHEBI

47780

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

EVMPD

SUB06725MIG

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

LACTMED

Clomipramine

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

ChEMBL

CHEMBL415

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

DRUG CENTRAL

701

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

INN

2238

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

MERCK INDEX

m3648

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

CLOMIPRAMINE

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

DAILYMED

NUV44L116D

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

MESH

D002997

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

DRUG BANK

DB01242

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

HSDB

7746

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

SMS_ID

100000084546

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

ECHA (EC/EINECS)

206-144-2

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

PUBCHEM

2801

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

NSC

169865

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

IUPHAR

2398

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

FDA UNII

NUV44L116D

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

CAS

303-49-1

Created by admin on Fri Dec 15 14:59:46 UTC 2023 , Edited by admin on Fri Dec 15 14:59:46 UTC 2023

PRIMARY

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5-HYDROXYTRYPTAMINE RECEPTOR 2A

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Amount:


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CLOMIPRAMINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Comments:

Metabolizing reaction by CYP2D6: 2- and 8-Hydroxylation

Amount:

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8-HYDROXYDEMETHYLCLOMIPRAMINE

METABOLITE -> PARENT

Amount:


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N-OXIDE CHLORIMIPRAMINE

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Amount:


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DESMETHYLCLOMIPRAMINE

METABOLITE ACTIVE -> PARENT

Interaction Type:

MAJOR

Amount:


					3DDA2BL4BG

8-HYDROXYCLOMIPRAMINE

METABOLITE -> PARENT

Amount:


					8R3702101D

DIDEMETHYLCLOMIPRAMINE

METABOLITE -> PARENT

Amount:


					51Z313GI3D

2-HYDROXYDEMETHYLCLOMIPRAMINE

METABOLITE -> PARENT

Amount:

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ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC