LATREPIRDINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H25N3
Molecular Weight	319.4433
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LATREPIRDINE

Structure Search

SMILES

CN1CCC2=C(C1)C3=C(C=CC(C)=C3)N2CCC4=CN=C(C)C=C4

InChI

InChIKey=JNODQFNWMXFMEV-UHFFFAOYSA-N

InChI=1S/C21H25N3/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17/h4-7,12-13H,8-11,14H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C21H25N3
Molecular Weight	319.4433
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:04:51 UTC 2023` Edited by `admin` on `Fri Dec 15 16:04:51 UTC 2023`
Record UNII	OD9237K1Z6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LATREPIRDINE

Official Name

English

Latrepirdine [WHO-DD]

Common Name

English

PF-01913539

Common Name

English

LATREPIRDINE [MART.]

Common Name

English

DIMEBOLIN [MI]

Common Name

English

DIMEBOLIN

Common Name

English

2,8-Dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

Systematic Name

English

latrepirdine [INN]

Common Name

English

1H-PYRIDO(4,3-B)INDOLE, 2,3,4,5-TETRAHYDRO-2,8-DIMETHYL-5-(2-(6-METHYL-3-PYRIDINYL)ETHYL)-

Systematic Name

English

DIMEBON

Common Name

English

LATREPIRDINE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

FDA ORPHAN DRUG

282309

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL589390

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

MERCK INDEX

m4495

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

Merck Index

NCI_THESAURUS

C78757

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

SMS_ID

100000124365

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

EPA CompTox

DTXSID20189705

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

INN

9207

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

EVMPD

SUB32096

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

MESH

C010119

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

CAS

3613-73-8

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

DRUG BANK

DB11725

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

FDA UNII

OD9237K1Z6

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

USAN

WW-164

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

PUBCHEM

197033

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

WIKIPEDIA

Latrepirdine

Created by admin on Fri Dec 15 16:04:51 UTC 2023 , Edited by admin on Fri Dec 15 16:04:51 UTC 2023

PRIMARY

Related Record Type Details


					Z3LSI83ND8

5-HYDROXYTRYPTAMINE RECEPTOR 6

TARGET -> INHIBITOR

Qualification:

Ki

Amount:


					1AG1A6ENX6

5-HYDROXYTRYPTAMINE RECEPTOR 7

TARGET -> INHIBITOR

Qualification:

Ki

Amount:


					28XBT591QG

HISTAMINE H1 RECEPTOR

TARGET -> INHIBITOR

Qualification:

IC50

Amount:


					XC55JSP2CX

HISTAMINE H2 RECEPTOR

TARGET->WEAK INHIBITOR

Qualification:

IC50

Amount:


					SEV29N8JND

POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2

OFF-TARGET->INHIBITOR

Amount:

Related Record Type Details


					OD9237K1Z6

ACTIVE MOIETY

Amount: