IMIPRAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H24N2
Molecular Weight	280.4073
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CN(C)CCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=BCGWQEUPMDMJNV-UHFFFAOYSA-N

InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H24N2
Molecular Weight	280.4073
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical
Record UNII	OGG85SX4E4
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

IMIPRAMINE

Official Name

English

MELIPRAMINE

Common Name

English

IMIPRAMINE [HSDB]

Common Name

English

CLOMIPRAMINE HYDROCHLORIDE IMPURITY B [EP IMPURITY]

Common Name

English

SERMONIL

Common Name

English

Showing 1 to 5 of 20 entries

Previous1 2 3 4Next

Show entries

Classification Tree

Code System

Code

Non-selective monoamine reuptake inhibitors

WHO-VATC

QN06AA02

Antidepressant

LIVERTOX

NBK547884

Non-selective monoamine reuptake inhibitors

WHO-ATC

N06AA02

Antidepressant Agent

NCI_THESAURUS

C94727

Established Pharmacologic Class

NDF-RT

N0000175752

Showing 1 to 5 of 5 entries

Previous1Next

Show entries

Code System

Code

Type

Description

DRUG CENTRAL

1427

PRIMARY

NCI_THESAURUS

C62039

PRIMARY

INN

793

PRIMARY

FDA UNII

OGG85SX4E4

PRIMARY

MESH

D007099

PRIMARY

Showing 1 to 5 of 22 entries

Previous1 2 3 4 5Next

Show entries

Related Record

Type

Details


					B46KUN2O9L

MATE-2

TRANSPORTER -> INHIBITOR


					DB7S4QSS89

Imipramine H-3

LABELED -> NON-LABELED

Amount:


					BKE5Q1J60U

IMIPRAMINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					MC34P30298

IMIPRAMINE PAMOATE

SALT/SOLVATE -> PARENT

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Comments:

Metabolizing reaction by CYP2D6: 2-Hydroxylation

Amount:

Showing 1 to 5 of 17 entries

Previous1 2 3 4Next

Show entries

Related Record

Type

Details


					TG537D343B

DESIPRAMINE

METABOLITE ACTIVE -> PARENT

Comments:

Imipramine has activities at both the serotonin and norepeinephrine transporters with greater affinity for the serotonin transporter while desipramine and 2-hydroxydesipramine have greater affinities for the norepinephrine transporter (Owens et al., 1997).

Amount: