MEZLOCILLIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H25N5O8S2
Molecular Weight	539.582
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MEZLOCILLIN

Structure Search

SMILES

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N3CCN(C3=O)S(C)(=O)=O)C4=CC=CC=C4)C(O)=O

InChI

InChIKey=YPBATNHYBCGSSN-VWPFQQQWSA-N

InChI=1S/C21H25N5O8S2/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30)/t12-,13-,14+,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H25N5O8S2
Molecular Weight	539.582
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:25:47 UTC 2023` Edited by `admin` on `Fri Dec 15 16:25:47 UTC 2023`
Record UNII	OH2O403D1G
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEZLOCILLIN

Official Name

English

mezlocillin [INN]

Common Name

English

MEZLOCILLIN [VANDF]

Common Name

English

4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 3,3-DIMETHYL-6-(((((3-(METHYLSULFONYL)-2-OXO-1-IMIDAZOLIDINYL)CARBONYL)AMINO)PHENYLACETYL)AMINO)-7-OXO-, (2S-(2.ALPHA.,5.ALPHA.,6.BETA.(S*)))

Common Name

English

Mezlocillin [WHO-DD]

Common Name

English

BAY-F-1353

Code

English

MEZLOCILLIN [MI]

Common Name

English

(2S,5R,6R)-3,3-Dimethyl-6-[(R)-2-[3-(methylsulfonyl)-2-oxo-1-imidazolidinecarboxamido]-2-phenylacetamido]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Systematic Name

English

MEZLOCILLIN [USAN]

Common Name

English

MEZLOCILLIN [MART.]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QJ01CA10

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

NCI_THESAURUS

C1558

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

WHO-ATC

J01CA10

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

LIVERTOX

633

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID1023316

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

DRUG CENTRAL

1795

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

PUBCHEM

656511

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

MESH

D008802

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

INN

3898

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

CAS

51481-65-3

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

RXCUI

6927

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

RxNorm

NCI_THESAURUS

C653

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

MERCK INDEX

m7520

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

Mezlocillin

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

CHEBI

6919

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

SMS_ID

100000081163

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

ECHA (EC/EINECS)

257-233-8

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

ChEMBL

CHEMBL1731

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

FDA UNII

OH2O403D1G

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

DRUG BANK

DB00948

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

EVMPD

SUB08938MIG

Created by admin on Fri Dec 15 16:25:47 UTC 2023 , Edited by admin on Fri Dec 15 16:25:47 UTC 2023

PRIMARY

Related Record Type Details


					3CWW8B5904

MEZLOCILLIN SODIUM MONOHYDRATE

SALT/SOLVATE -> PARENT

Amount:


					5840721PJZ

OAT-2

TRANSPORTER -> INHIBITOR

Comments:

Showed high in vivo inhibition potential due to the high unbound plasma concentrations attained at clinically relevant doses.

Amount:

Related Record Type Details


					OH2O403D1G

ACTIVE MOIETY