REMIFENTANIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H28N2O5
Molecular Weight	376.4467
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of REMIFENTANIL

Structure Search

SMILES

CCC(=O)N(C1=CC=CC=C1)C2(CCN(CCC(=O)OC)CC2)C(=O)OC

InChI

InChIKey=ZTVQQQVZCWLTDF-UHFFFAOYSA-N

InChI=1S/C20H28N2O5/c1-4-17(23)22(16-8-6-5-7-9-16)20(19(25)27-3)11-14-21(15-12-20)13-10-18(24)26-2/h5-9H,4,10-15H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C20H28N2O5
Molecular Weight	376.4467
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:13:30 UTC 2023` Edited by `admin` on `Sat Dec 16 17:13:30 UTC 2023`
Record UNII	P10582JYYK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

REMIFENTANIL

Official Name

English

GI 87084X

Code

English

RAMIFENTANYL

Common Name

English

Remifentanil [WHO-DD]

Common Name

English

REMIFENTANIL [MI]

Common Name

English

ULTIVA-

Common Name

English

remifentanil [INN]

Common Name

English

REMIFENTANYL

Common Name

English

REMIFENTANIL [VANDF]

Common Name

English

IDS-NR-005

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C67413

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

WHO-VATC

QN01AH06

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

WIKIPEDIA

List_of_fentanyl_analogues

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

NDF-RT

N0000175690

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

WHO-ATC

N01AH06

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

DEA NO.

9739

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

NDF-RT

N0000175684

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

NCI_THESAURUS

C1506

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C66513

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

FDA UNII

P10582JYYK

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

DRUG BANK

DB00899

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

ChEMBL

CHEMBL1005

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

MERCK INDEX

m9521

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

Merck Index

DRUG CENTRAL

2363

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

LACTMED

Remifentanil

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

CAS

132875-61-7

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

WEB RESOURCE

REMIFENTANIL

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

EVMPD

SUB10272MIG

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

CHEBI

8802

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

IUPHAR

7292

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

MESH

C071741

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

INN

6924

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

RXCUI

73032

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

RxNorm

WIKIPEDIA

REMIFENTANIL

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. Remifentanil is used as an opioid analgesic that has a rapid onset and rapid recovery time. It has been used effectively during craniotomies, spinal surgery, cardiac surgery, and gastric bypass surgery. While opiates function similarly, with respect to analgesia, the pharmacokinetics of remifentanil allows for quicker post-operative recovery.

SMS_ID

100000089165

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

EPA CompTox

DTXSID00157826

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

PUBCHEM

60815

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

DAILYMED

P10582JYYK

Created by admin on Sat Dec 16 17:13:31 UTC 2023 , Edited by admin on Sat Dec 16 17:13:31 UTC 2023

PRIMARY

Related Record Type Details


					1PE72K8X46

MU-TYPE OPIOID RECEPTOR

TARGET -> AGONIST

Comments:

Potency higher than fentanyl (IC50=1.23 NM) fast onset and short duration of action.

Qualification:

IC50

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					5V444H5WIC

REMIFENTANIL HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					OH8N7NE9ZG

METABOLITE INACTIVE -> PARENT

Interaction Type:

MINOR

Amount:


					E1EZX4S2E1

REMIFENTANIL ACID

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR

Amount:

Related Record Type Details


					P10582JYYK

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC