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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H10ClN5O2
Molecular Weight 267.672
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CENOBAMATE

SMILES

NC(=O)O[C@@H](CN1N=CN=N1)C2=C(Cl)C=CC=C2

InChI

InChIKey=GFHAXPJGXSQLPT-VIFPVBQESA-N
InChI=1S/C10H10ClN5O2/c11-8-4-2-1-3-7(8)9(18-10(12)17)5-16-14-6-13-15-16/h1-4,6,9H,5H2,(H2,12,17)/t9-/m0/s1

HIDE SMILES / InChI
Molecular Formula C10H10ClN5O2
Molecular Weight 267.672
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:43:57 UTC 2023
Edited
by admin
on Fri Dec 15 19:43:57 UTC 2023
Record UNII
P85X70RZWS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CENOBAMATE
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
2H-TETRAZOLE-2-ETHANOL, .ALPHA.-(2-CHLOROPHENYL)-, CARBAMATE (ESTER), (.ALPHA.R)-
Systematic Name English
YKP-3089
Code English
CARBAMIC ACID (R)-(+)-1-(2-CHLOROPHENYL)-2-(2H-TETRAZOL-2-YL)ETHYL ESTER
Systematic Name English
cenobamate [INN]
Common Name English
XCOPRI
Brand Name English
2H-TETRAZOLE-2-ETHANOL, .ALPHA.-(2-CHLOROPHENYL)-, 2-CARBAMATE, (.ALPHA.R)-
Systematic Name English
2H-TETRAZOLE-2-ETHANOL, ALPHA-(2-CHLOROPHENYL)-, YL)ETHYL)CARBAMATE CARBAMATE (ESTER), (.ALPHA.R)-
Systematic Name English
CENOBAMATE [ORANGE BOOK]
Common Name English
CENOBAMATE [USAN]
Common Name English
(1R)-1-(2-CHLOROPHENYL)-2-(TETRAZOL-YL)ETHYL)CARBAMATE
Common Name English
YKP3089
Code English
(1R)-1-(2-Chlorophenyl)-2-(2H-tetrazol-2-yl)ethyl carbamate
Systematic Name English
Cenobamate [WHO-DD]
Common Name English
CENOBAMATE [MI]
Common Name English
Classification Tree Code System Code
DEA NO. 2720
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
Code System Code Type Description
CAS
913088-80-9
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
NCI_THESAURUS
C174837
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
SMS_ID
100000174917
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
USAN
DE-83
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
DAILYMED
P85X70RZWS
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
FDA UNII
P85X70RZWS
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
DRUG CENTRAL
5355
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
DRUG BANK
DB06119
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
PUBCHEM
11962412
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
INN
10116
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
LACTMED
Cenobamate
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
MERCK INDEX
m12177
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
EPA CompTox
DTXSID001027948
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
WIKIPEDIA
Cenobamate
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
RXCUI
2265690
Created by admin on Fri Dec 15 19:43:57 UTC 2023 , Edited by admin on Fri Dec 15 19:43:57 UTC 2023
PRIMARY
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Structure of CENOBAMATE
EXCRETED UNCHANGED
AMOUNT EXCRETED
URINE
CYTOCHROME P450 2C19
METABOLIC ENZYME -> SUBSTRATE
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METABOLIC ENZYME -> SUBSTRATE
GABAA RECEPTOR
TARGET->POSITIVE ALLOSTERIC MODULATOR (PAM)
CYTOCHROME P450 2C8
METABOLIC ENZYME -> INDUCER
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
Cenobamate mainly binds with human albumin protein and not with α1-acid glycoprotein.
BINDING
Related Record Type Details
Structure of (2S,3S,4S,5R,6R)-6-(((1R)-1-(2-CHLOROPHENYL)-2-(TETRAZOL-2-YL)ETHOXY)CARBONYLAMINO)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID
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Structure of (2S,3S,4S,5R,6R)-6-((1R)-1-(2-CHLOROPHENYL)-2-(TETRAZOL-2-YL)ETHOXY)-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID
METABOLITE -> PARENT
URINE
Related Record Type Details
Structure of CENOBAMATE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Tmax PHARMACOKINETIC SINGLE- OR MULTIPLE-DOSE ADMINISTRATION

FASTED STATE

blood to plasma ratio PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
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