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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H22N2O2
Molecular Weight 250.3367
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIVASTIGMINE

SMILES

CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C

InChI

InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N
InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1

HIDE SMILES / InChI
Molecular Formula C14H22N2O2
Molecular Weight 250.3367
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:53:25 UTC 2023
Edited
by admin
on Fri Dec 15 15:53:25 UTC 2023
Record UNII
PKI06M3IW0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RIVASTIGMINE
EMA EPAR   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
RIVASTIGMINE [EP MONOGRAPH]
Common Name English
ENA-713D
Code English
RIVASTIGMINE [MART.]
Common Name English
RIVASTIGMINE 1 A PHARMA
Brand Name English
RIVASTIGMINE 3M HEALTH CARE LTD
Brand Name English
Rivastigmine [WHO-DD]
Common Name English
NIMVASTID
Brand Name English
SDZ-212-713
Code English
SDZ-212713
Code English
RIVASTIGMINE [ORANGE BOOK]
Common Name English
RIVASTIGMINE TEVA
Brand Name English
PROMETAX
Brand Name English
ONO-2540
Code English
RIVASTIGMINE [EMA EPAR]
Common Name English
RIVASTIGMINE [JAN]
Common Name English
(S)-3-(1-(DIMETHYLAMINO)ETHYL)PHENYL ETHYLMETHYLCARBAMATE
Systematic Name English
RIVASTIGMINE [MI]
Common Name English
RIVASTIGMINE SANDOZ
Brand Name English
M-((S)-1-(DIMETHYLAMINO)ETHYL)PHENYL ETHYLMETHYLCARBAMATE
Systematic Name English
RIVASTIGMINE HEXAL
Brand Name English
RIVASTIGMINE [USAN]
Common Name English
RIVASTIGMINE [VANDF]
Common Name English
rivastigmine [INN]
Common Name English
EXELON
Brand Name English
RIVASTIGMINE [USP-RS]
Common Name English
RIVASTIGMINE [USP MONOGRAPH]
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS RIVASTIGMINE SANDOZ
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS EXELON (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
WHO-VATC QN06DA03
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE TEVA (WITHDRAWN: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE SANDOZ (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE HEXAL (AUTHORIZED: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS NIMVASTID (AUTHORIZED: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS PROMETAX (AUTHORIZED: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS NIMVASTID (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
LIVERTOX NBK548942
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS EXELON (AUTHORIZED: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE HEXAL (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
NDF-RT N0000000177
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
WHO-ATC N06DA03
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS PROMETAX (AUTHORIZED: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
NDF-RT N0000175723
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
NCI_THESAURUS C47792
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS EXELON (AUTHORIZED: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE 3M HEALTH CARE LTD (WITHDRAWN: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS NIMVASTID (AUTHORIZED: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS PROMETAX (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE 1A PHARMA (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE 1 A PHARMA (AUTHORIZED: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE 1 A PHARMA (AUTHORIZED: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE SANDOZ (AUTHORIZED: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE TEVA (WITHDRAWN: PARKINSON DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE TEVA (WITHDRAWN: DEMENTIA)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
EMA ASSESSMENT REPORTS RIVASTIGMINE HEXAL (AUTHORIZED: ALZHEIMER DISEASE)
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
Code System Code Type Description
WIKIPEDIA
RIVASTIGMINE
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
DAILYMED
PKI06M3IW0
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
INN
7562
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
PUBCHEM
77991
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
ChEMBL
CHEMBL636
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
CAS
123441-03-2
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
IUPHAR
6602
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
MERCK INDEX
m9639
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY Merck Index
SMS_ID
100000089185
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
FDA UNII
PKI06M3IW0
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
USAN
II-99
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
DRUG CENTRAL
2392
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
RS_ITEM_NUM
1604836
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
CHEBI
8874
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
CHEBI
64358
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
RXCUI
183379
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY RxNorm
EVMPD
SUB10345MIG
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
EPA CompTox
DTXSID7023564
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
DRUG BANK
DB00989
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
MESH
C072506
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
NCI_THESAURUS
C66519
Created by admin on Fri Dec 15 15:53:25 UTC 2023 , Edited by admin on Fri Dec 15 15:53:25 UTC 2023
PRIMARY
Related Record Type Details
ACETYLCHOLINESTERASE HUMAN
TARGET -> INHIBITOR
Structure of RIVASTIGMINE
EXCRETED UNCHANGED
No parent drug was detected in urine.
URINE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
BUTYRYLCHOLINESTERASE
TARGET -> INHIBITOR
Structure of RIVASTIGMINE TARTRATE
SALT/SOLVATE -> PARENT
Structure of RIVASTIGMINE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
Related Record Type Details
Structure of NAP-226-90
METABOLITE -> PARENT
PLASMA
Structure of NAP-226-90 O-SULFATE
METABOLITE -> PARENT
MAJOR
URINE
Related Record Type Details
Structure of 3-VINYLPHENYL ETHYL(METHYL)CARBAMATE
IMPURITY -> PARENT
Structure of NAP-226-90
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-(1-(DIMETHYLAMINO)ETHYL)PHENYL DIMETHYLCARBAMATE, (1S)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of NAP-226-90
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-(1-(DIMETHYLAMINO)ETHYL)PHENYL DIMETHYLCARBAMATE, (1S)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 1-(3-((ETHYL(METHYL)CARBAMOYL)OXY)PHENYL)-N,N,N-TRIMETHYLETHANAMINIUM CHLORIDE, (S)-
IMPURITY -> PARENT
Structure of RIVASTIGMINE, (R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-ACETYLPHENYL ETHYL(METHYL)CARBAMATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of RIVASTIGMINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Tmax PHARMACOKINETIC ORAL ADMINISTRATION

Tmax PHARMACOKINETIC FED CONDITION

ORAL ADMINISTRATION

Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
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HHS VULNERABILITY DISCLOSURE
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