EPINASTINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H15N3
Molecular Weight	249.3104
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NCC2N1C3=C(CC4=C2C=CC=C4)C=CC=C3

InChI

InChIKey=WHWZLSFABNNENI-UHFFFAOYSA-N

InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18)

HIDE SMILES / InChI

Molecular Formula	C16H15N3
Molecular Weight	249.3104
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:59:41 UTC 2023` Edited by `admin` on `Fri Dec 15 15:59:41 UTC 2023`
Record UNII	Q13WX941EF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EPINASTINE

Official Name

English

EPINASTINE [MI]

Common Name

English

3-AMINO-9,13B-DIHYDRO-1H-DIBENZ(C,F)IMIDAZO(1,5-A)AZEPINE

Common Name

English

9,13B-DIHYDRO-1H-DIBENZ(C,F)IMIDAZO(1,5-A)AZEPIN-3-AMINE

Common Name

English

Epinastine [WHO-DD]

Common Name

English

WAL-801

Code

English

PURIVIST

Brand Name

English

EPINASTINE [VANDF]

Common Name

English

epinastine [INN]

Common Name

English

(±)-EPINASTINE

Common Name

English

1H-DIBENZ(C,F)IMIDAZO(1,5-A)AZEPIN-3-AMINE, 9,13B-DIHYDRO-

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

R06AX24

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

NDF-RT

N0000000122

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

NDF-RT

N0000000190

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

NDF-RT

N0000175883

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

WHO-VATC

QR06AX24

Created by admin on Fri Dec 15 15:59:42 UTC 2023 , Edited by admin on Fri Dec 15 15:59:42 UTC 2023

NDF-RT

N0000175519

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

NDF-RT

N0000175628

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

WHO-ATC

S01GX10

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

WHO-VATC

QS01GX10

Created by admin on Fri Dec 15 15:59:42 UTC 2023 , Edited by admin on Fri Dec 15 15:59:42 UTC 2023

Code System Code Type Description

RXCUI

39684

Created by admin on Fri Dec 15 15:59:42 UTC 2023 , Edited by admin on Fri Dec 15 15:59:42 UTC 2023

PRIMARY

RxNorm

IUPHAR

7176

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

INN

5953

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

DRUG CENTRAL

1027

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

CAS

134507-59-8

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

SUPERSEDED

CHEBI

51032

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

SMS_ID

100000080472

Created by admin on Fri Dec 15 15:59:42 UTC 2023 , Edited by admin on Fri Dec 15 15:59:42 UTC 2023

PRIMARY

ChEMBL

CHEMBL1106

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

EVMPD

SUB06567MIG

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

PUBCHEM

3241

Created by admin on Fri Dec 15 15:59:42 UTC 2023 , Edited by admin on Fri Dec 15 15:59:42 UTC 2023

PRIMARY

DAILYMED

Q13WX941EF

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

MESH

C053090

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

NCI_THESAURUS

C65515

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

MERCK INDEX

m4943

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

Merck Index

FDA UNII

Q13WX941EF

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

CAS

80012-43-7

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

WIKIPEDIA

EPINASTINE

Created by admin on Fri Dec 15 15:59:42 UTC 2023 , Edited by admin on Fri Dec 15 15:59:42 UTC 2023

PRIMARY

EPA CompTox

DTXSID2048371

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

DRUG BANK

DB00751

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

LACTMED

Epinastine

Created by admin on Fri Dec 15 15:59:41 UTC 2023 , Edited by admin on Fri Dec 15 15:59:41 UTC 2023

PRIMARY

Related Record Type Details


					5HDI847257

EPINASTINE, (S)-

ENANTIOMER -> RACEMATE


					GFM415S5XL

EPINASTINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					79UN26Y71B

EPINASTINE, (R)-

ENANTIOMER -> RACEMATE


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE


					Q13WX941EF

EPINASTINE

EXCRETED UNCHANGED

Comments:

Epinastine is mainly excreted unchanged. About 55% of an intravenous dose is recovered unchanged in the urine with about 30% in feces.

Qualification:

FECAL

Amount:


					Q13WX941EF

EPINASTINE

EXCRETED UNCHANGED

Comments:

Epinastine is mainly excreted unchanged. About 55% of an intravenous dose is recovered unchanged in the urine with about 30% in feces.

Qualification:

URINE

Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE


					0UY97CSG1T

CYTOCHROME P450 2B6

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					4O6LIW7G3N

EPINASTINE HYDROBROMIDE

SALT/SOLVATE -> PARENT


					28XBT591QG

HISTAMINE H1 RECEPTOR

TARGET->ANTAGONIST

Related Record Type Details


					Q13WX941EF

EPINASTINE

ACTIVE MOIETY

Name	Property Type	Parameters
Tmax	PHARMACOKINETIC	SINGLE DOSE

Biological Half-life	PHARMACOKINETIC	SINGLE DOSE