CISPLATIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	2Cl.Pt.2H3N
Molecular Weight	300.051
Optical Activity	NONE
Additional Stereochemistry	Yes
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0
Stereo Comments	SP-4-2

SHOW SMILES / InChI

Structure of CISPLATIN

Structure Search

SMILES

N.N.[Cl-].[Cl-].[Pt++]

InChI

InChIKey=LXZZYRPGZAFOLE-UHFFFAOYSA-L

InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	H3N
Molecular Weight	17.0305
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Pt
Molecular Weight	195.084
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:18:53 UTC 2023` Edited by `admin` on `Fri Dec 15 15:18:53 UTC 2023`
Record UNII	Q20Q21Q62J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CISPLATIN

Official Name

English

CIS-DIAMMINEDICHLOROPLATINUM II

Common Name

English

CISPLATIN [USAN]

Common Name

English

CISPLATIN [USP-RS]

Common Name

English

cisplatin [INN]

Common Name

English

CIS-DIAMMINEDICHLOROPLATINUM [WHO-IP]

Common Name

English

PEYRONE'S SALT

Common Name

English

FAULDISCIPLA

Common Name

English

CISPLATIN [MART.]

Common Name

English

CISPLATIN [EP IMPURITY]

Common Name

English

CISPLATINUM

Common Name

English

PLATINOL

Brand Name

English

CIS-DDP

Code

English

NSC-119875

Code

English

CISPLATIN [IARC]

Common Name

English

CISPLATIN [EP MONOGRAPH]

Common Name

English

(SP-4-2)-DIAMMINEDICHLOROPLATINUM [WHO-IP]

Common Name

English

cis-Diamminedichloroplatinum

Common Name

English

CISPLATIN [WHO-DD]

Common Name

English

INT-230-6 COMPONENT CISPLATIN

Code

English

INT230-6 COMPONENT CISPLATIN

Code

English

LIPLACIS

Brand Name

English

CISPLATIN [WHO-IP]

Common Name

English

CISPLATIN [ORANGE BOOK]

Common Name

English

CISPLATIN [USP MONOGRAPH]

Common Name

English

CIS-PLATIN

Common Name

English

CDDP

Common Name

English

CISPLATIN [JAN]

Common Name

English

CISPLATINUM [WHO-IP LATIN]

Common Name

English

CISPLATIN [HSDB]

Common Name

English

CISPLATIN [MI]

Common Name

English

PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C798

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

WHO-ATC

L01XA01

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

238607

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

221906

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

WHO-VATC

QL01XA01

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

NDF-RT

N0000175413

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

134800

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

536616

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

447514

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

NDF-RT

N0000175073

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

EU-Orphan Drug

EU/3/13/1169

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

867921

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

LIVERTOX

NBK548160

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

557716

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

NCI_THESAURUS

C1450

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

783620

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

FDA ORPHAN DRUG

133200

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

Code System Code Type Description

MESH

D002945

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

EPA CompTox

DTXSID4024983

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

CAS

15663-27-1

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

SMS_ID

100000088223

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

ChEMBL

CHEMBL11359

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

DRUG CENTRAL

4392

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

NSC

119875

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

NCI_THESAURUS

C376

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

FDA UNII

Q20Q21Q62J

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

PUBCHEM

84691

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

LACTMED

Cisplatin

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

HSDB

3939

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

ECHA (EC/EINECS)

239-733-8

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

IUPHAR

5343

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

INN

4426

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

CHEBI

27899

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

CISPLATIN

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

Description: White to yellowish crystals or a yellow powder.Solubility: Slightly soluble in water; sparingly soluble in dimethylformamide R; practically insoluble in methanol R.Category: Cytotoxic drug.Storage: Cisplatin should be kept in a tightly closed container, protected from light, and stored at a temperature between 2 and 8?C.Additional information: CAUTION: Cisplatin must be handled with care, avoiding contact with the skin and inhalation of airborneparticles.When heated, it blackens at about 270 ?C with decomposition.

WIKIPEDIA

CISPLATIN

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

RS_ITEM_NUM

1134357

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

DRUG BANK

DB00515

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

MERCK INDEX

m3586

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

Merck Index

DAILYMED

Q20Q21Q62J

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

RXCUI

2555

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

RxNorm

EVMPD

SUB07483MIG

Created by admin on Fri Dec 15 15:18:53 UTC 2023 , Edited by admin on Fri Dec 15 15:18:53 UTC 2023

PRIMARY

Related Record Type Details


					Y49M64GZ4Q

MRP-1

TRANSPORTER -> SUBSTRATE

Amount:


					1YV0492L5Z

MRP-3

TRANSPORTER -> SUBSTRATE


					4AF605U6JN

MRP-2

TRANSPORTER -> SUBSTRATE


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> SUBSTRATE


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					V7JK4F3V8U

MONOHYDROXYCISPLATIN

METABOLITE ACTIVE -> PRODRUG

Comments:

OCCURS INTRACELLULARLY


					5A6L8IU8VT

PLATINATE(4-), DIAMMINEDICHLOROBIS(N-PHOSPHONOCARBAMATO(3-)-.KAPPA.O)-, HYDROGEN (1:4), (OC-6-33)-

PRODRUG -> METABOLITE ACTIVE


					6L6R7H31YE

MONOAQUACISPLATINUM

METABOLITE ACTIVE -> PRODRUG

Comments:

OCCURS INTRACELLULARLY

Related Record Type Details


					BG3F62OND5

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					BW0OY6ZTD4

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					G42B13S0D6

TRICHLOROAMMINEPLATINATE

IMPURITY -> PARENT

Interaction Type:

ASSAY (HPLC)

Amount:

Related Record Type Details


					Q20Q21Q62J

CISPLATIN

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC