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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H11I4NO4
Molecular Weight 776.87
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEVOTHYROXINE

SMILES

N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O

InChI

InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N
InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

HIDE SMILES / InChI
Molecular Formula C15H11I4NO4
Molecular Weight 776.87
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:16:27 UTC 2023
Edited
by admin
on Fri Dec 15 15:16:27 UTC 2023
Record UNII
Q51BO43MG4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEVOTHYROXINE
HSDB   USP-RS   VANDF   WHO-DD  
Common Name English
SYNTHETIC LEVOTHYROXINE
Common Name English
LEVOTHYROXINE [VANDF]
Common Name English
O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-L-TYROSINE
Systematic Name English
LIOTHYRONINE SODIUM IMPURITY A [EP IMPURITY]
Common Name English
SK&F 1-6528
Code English
Levothyroxine [WHO-DD]
Common Name English
LEVOTHYROXINE [USP-RS]
Common Name English
LEVOTHYROXIN
Common Name English
L-THYROXINE
Common Name English
NSC-36397
Code English
THYROXINE, L-
Common Name English
3,5,3',5'-TETRAIODO-L-THYRONINE
Systematic Name English
T4
Common Name English
L-TYROSINE, O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-
Systematic Name English
THYROXINE
MI  
Common Name English
(-)-3-(4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL)ALANINE
Systematic Name English
LEVOTHYROXINE [HSDB]
Common Name English
THYROXINE [MI]
Common Name English
Classification Tree Code System Code
LOINC 14921-1
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 73557-1
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
CFR 21 CFR 520.1248
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 27000-9
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 35228-6
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 14920-3
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 3024-7
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
CFR 21 CFR 862.1685
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 18.8
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 83121-4
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 3028-8
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 83119-8
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
WHO-ATC H03AA03
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
NDF-RT N0000007632
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LIVERTOX 958
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 20451-1
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 6892-4
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 31145-6
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 31144-9
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 35226-0
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
NCI_THESAURUS C1553
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 83120-6
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 70217-5
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
NCI_THESAURUS C886
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 38506-2
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
WHO-VATC QH03AA03
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 70152-4
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 53350-5
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
CFR 21 CFR 862.1700
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 83122-2
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 3027-0
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
CFR 21 CFR 862.1695
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 53349-7
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 3025-4
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
LOINC 3026-2
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
NDF-RT N0000175945
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
Code System Code Type Description
FDA UNII
Q51BO43MG4
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
CHEBI
305790
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
CAS
51-48-9
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
NCI_THESAURUS
C62080
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
DRUG BANK
DB00451
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
CHEBI
18332
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
NSC
36397
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
ChEMBL
CHEMBL1624
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
LACTMED
Levothyroxine
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
DRUG CENTRAL
2646
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
CHEBI
30660
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
HSDB
3108
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-101-1
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
EVMPD
SUB02917MIG
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
RXCUI
10582
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY RxNorm
CHEBI
58448
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
IUPHAR
2635
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
SMS_ID
100000086128
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
WIKIPEDIA
LEVOTHYROXINE
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
DAILYMED
Q51BO43MG4
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
MERCK INDEX
m10840
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY Merck Index
MESH
D013974
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
EPA CompTox
DTXSID8023214
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
EVMPD
SUB127246
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
PUBCHEM
5819
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
RS_ITEM_NUM
1365000
Created by admin on Fri Dec 15 15:16:27 UTC 2023 , Edited by admin on Fri Dec 15 15:16:27 UTC 2023
PRIMARY
Related Record Type Details
MONOCARBOXYLATE TRANSPORTER 8
TRANSPORTER -> SUBSTRATE
OATP1B1
TRANSPORTER -> INHIBITOR
OATP1B1
TRANSPORTER -> SUBSTRATE
Related Record Type Details
Structure of LIOTHYRONINE
METABOLITE ACTIVE -> PARENT
MAJOR
Thyroid
PRODRUG -> METABOLITE ACTIVE
Structure of 3,3'-DIIODOTHYRONINE, L-
METABOLITE INACTIVE -> PARENT
Structure of LIOTHYRONINE
METABOLITE ACTIVE -> PARENT
Related Record Type Details
Structure of LIOTHYRONINE SODIUM
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of LEVOTHYROXINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
ORAL BIOAVAILABILITY PHARMACOKINETIC ORAL SOLUTION
PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC T(3)
PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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