VINORELBINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C45H54N4O8
Molecular Weight	778.9323
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VINORELBINE

Structure Search

SMILES

[H][C@@]12N3CC[C@@]14C5=CC(=C(OC)C=C5N(C)[C@@]4([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]6(C[C@H]7CN(CC(CC)=C7)CC8=C6NC9=C8C=CC=C9)C(=O)OC

InChI

InChIKey=GBABOYUKABKIAF-IELIFDKJSA-N

InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C45H54N4O8
Molecular Weight	778.9323
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:57:17 UTC 2023` Edited by `admin` on `Fri Dec 15 15:57:17 UTC 2023`
Record UNII	Q6C979R91Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VINORELBINE

Official Name

English

VINORELBINE TARTRATE IMPURITY J [EP IMPURITY]

Common Name

English

NAVELBIN

Common Name

English

Vinorelbine [WHO-DD]

Common Name

English

VINORELBINE [ORANGE BOOK]

Common Name

English

vinorelbine [INN]

Common Name

English

ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 4-(ACETYLOXY)-6,7-DIDEHYDRO-15-((2R,6R,8S)-4-ETHYL-1,3,6,7,8,9-HEXAHYDRO-8-(METHOXYCARBONYL)-2,6-METHANO-2H-AZECINO(4,3-B)INDOL-8-YL)-3-HYDROXY-16-METHOXY-1-METHYL-, METHYL ESTER, (2.BETA.,3.BETA.,4.BETA.,5.ALPHA.,12R,

Systematic Name

English

4-DEOXY-3,4-DIDEHYDROVINCALEUKOBLASTINE

Systematic Name

English

C'-NORVINCALEUKOBLASTINE, 3',4'-DIDEHYDRO-4'-DEOXY-

Systematic Name

English

NSC-760087

Code

English

VINORELBINE [HSDB]

Common Name

English

VINORELBINE [MI]

Common Name

English

VINORELBINE [VANDF]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000007780

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

NCI_THESAURUS

C67422

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

NCI_THESAURUS

C932

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

NDF-RT

N0000007780

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

NDF-RT

N0000175612

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

FDA ORPHAN DRUG

540716

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

WHO-ATC

L01CA04

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

FDA ORPHAN DRUG

588417

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

LIVERTOX

1031

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

WHO-VATC

QL01CA04

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

Code System Code Type Description

CAS

71486-22-1

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

EPA CompTox

DTXSID8040640

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

SMS_ID

100000079114

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

MERCK INDEX

m11457

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

Merck Index

ChEMBL

CHEMBL553025

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

FDA UNII

Q6C979R91Y

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

RXCUI

39541

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

RxNorm

DRUG BANK

DB00361

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

EVMPD

SUB00069MIG

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

PUBCHEM

5311497

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

DRUG CENTRAL

2827

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

IUPHAR

7105

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

DAILYMED

Q6C979R91Y

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

INN

6054

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

NCI_THESAURUS

C1275

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

WIKIPEDIA

VINORELBINE

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

CHEBI

480999

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

MESH

C030852

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

LACTMED

Vinorelbine

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

HSDB

7665

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

NSC

760087

Created by admin on Fri Dec 15 15:57:17 UTC 2023 , Edited by admin on Fri Dec 15 15:57:17 UTC 2023

PRIMARY

Related Record Type Details


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR


					74UG0EWZ60

TUBULIN BETA CHAIN

TARGET -> INHIBITOR


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					253GQW851Q

VINORELBINE TARTRATE

SALT/SOLVATE -> PARENT


					40AHO2C6DG

VILANTEROL TRIFENATATE

TRANSPORTER -> SUBSTRATE

Related Record Type Details


					7E57MEP1M9

(6RS)-4-DEOXY-3,4-DIDEHYDRO-8-NORVINCALEUKOBLASTINE 6-OXIDE

METABOLITE -> PARENT

Related Record Type Details


					253GQW851Q

VINORELBINE TARTRATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					Q6C979R91Y

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC