BIMATOPROST

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H37NO4
Molecular Weight	415.5656
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of BIMATOPROST

Structure Search

SMILES

CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC2=CC=CC=C2

InChI

InChIKey=AQOKCDNYWBIDND-FTOWTWDKSA-N

InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C25H37NO4
Molecular Weight	415.5656
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	2
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:45:12 UTC 2023` Edited by `admin` on `Fri Dec 15 15:45:12 UTC 2023`
Record UNII	QXS94885MZ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BIMATOPROST

Official Name

English

BIMATOPROST [MART.]

Common Name

English

PROSTAMIDE

Brand Name

English

GANFORT COMPONENT BIMATOPROST

Brand Name

English

(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-5-heptenamide

Systematic Name

English

AGN 192024

Code

English

bimatoprost [INN]

Common Name

English

AGN-192024

Code

English

BIMATOPROST [USAN]

Common Name

English

BIMATOPROST [ORANGE BOOK]

Common Name

English

LATISSE

Brand Name

English

5-HEPTENAMIDE, 7-(3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYL-1-PENTENYL)CYCLOPENTYL)-N-ETHYL-, (1R-1(.ALPHA.(Z),2.BETA.(1E,3S*)3.ALPHA.,5.ALPHA.))-

Common Name

English

BIMATOPROST [INCI]

Common Name

English

BIMATOPROST [MI]

Common Name

English

BIMATOPROST [VANDF]

Common Name

English

LUMIGAN

Brand Name

English

BIMATOPROST [JAN]

Common Name

English

BIMATOPROST COMPONENT OF GANFORT

Brand Name

English

BIMATOPROST [EMA EPAR]

Common Name

English

Bimatoprost [WHO-DD]

Common Name

English

DURYSTA

Brand Name

English

Classification Tree Code System Code

NDF-RT

N0000007706

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

WHO-ATC

S01EE03

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

NDF-RT

N0000007706

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

NCI_THESAURUS

C78568

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

NDF-RT

N0000007706

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

NCI_THESAURUS

C29705

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

WHO-VATC

QS01EE03

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

EMA ASSESSMENT REPORTS

LUMIGAN (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

EMA ASSESSMENT REPORTS

GANFORT (AUTHORIZED: OCULAR HYPERTENSION0

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

EMA ASSESSMENT REPORTS

BIMATOPROST (AUTHORIZED: OCULAR HYPERTENSION)

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

EMA ASSESSMENT REPORTS

LUMIGAN (AUTHORIZED: OCULAR HYPERTENSION)

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

NDF-RT

N0000175454

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

Code System Code Type Description

INN

8035

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

WIKIPEDIA

BIMATOPROST

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

DAILYMED

QXS94885MZ

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

SMS_ID

100000089302

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

LACTMED

Bimatoprost

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

EVMPD

SUB12470MIG

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

IUPHAR

1958

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

PUBCHEM

5311027

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

FDA UNII

QXS94885MZ

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

ChEMBL

CHEMBL1200963

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

EPA CompTox

DTXSID30895042

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

CHEBI

51230

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

NCI_THESAURUS

C47414

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

CAS

155206-00-1

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

USAN

LL-78

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

DRUG BANK

DB00905

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

DRUG CENTRAL

371

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

MESH

C420823

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

RXCUI

283810

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m2495

Created by admin on Fri Dec 15 15:45:12 UTC 2023 , Edited by admin on Fri Dec 15 15:45:12 UTC 2023

PRIMARY

Merck Index

Related Record Type Details


					D381C4K8ZW

PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE

TARGET -> AGONIST


					7L8YW0VG16

PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE

TARGET -> AGONIST


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					5NTX6739W3

PROSTAGLANDIN F2-ALPHA RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					P14259CVZG

7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E)-3-OXO-5-PHENYL-1-PENTEN-1-YL)CYCLOPENTYL)-N-ETHYL-5-HEPTENAMIDE, (5Z)-

IMPURITY -> PARENT


					9UHL27LCT4

BIMATOPROST ACID METHYL ESTER

IMPURITY -> PARENT


					JY922N486Z

BIMATOPROST, (15R)-

IMPURITY -> PARENT

Amount:


					2683MK55HG

BIMATOPROST ACID

IMPURITY -> PARENT

Related Record Type Details


					QXS94885MZ

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC