FENCLONINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C9H10ClNO2
Molecular Weight	199.634
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENCLONINE

Structure Search

SMILES

NC(CC1=CC=C(Cl)C=C1)C(O)=O

InChI

InChIKey=NIGWMJHCCYYCSF-UHFFFAOYSA-N

InChI=1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C9H10ClNO2
Molecular Weight	199.634
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:36:02 UTC 2023` Edited by `admin` on `Fri Dec 15 17:36:02 UTC 2023`
Record UNII	R5J7E3L9SP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FENCLONINE

Official Name

English

CP-10188

Code

English

NSC-77370

Code

English

fenclonine [INN]

Common Name

English

FENCLONINE [HSDB]

Common Name

English

DL-3-(P-CHLOROPHENYL)ALANINE

Systematic Name

English

P-CHLOROPHENYLALANINE, DL-

Common Name

English

ALANINE, 3-(4-CHLOROPHENYL)-, DL-

Systematic Name

English

FENCLONINE [USAN]

Common Name

English

CP-10,188

Code

English

FENCLONINE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C471

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

Code System Code Type Description

INN

2382

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

WIKIPEDIA

FENCLONINE

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

SMS_ID

100000081268

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

CAS

7424-00-2

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

NCI_THESAURUS

C81112

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

EPA CompTox

DTXSID4045139

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

PUBCHEM

4652

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

MESH

D010134

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

ECHA (EC/EINECS)

231-051-9

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

ChEMBL

CHEMBL1256351

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

EVMPD

SUB07551MIG

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

NSC

77370

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

FDA UNII

R5J7E3L9SP

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

HSDB

7747

Created by admin on Fri Dec 15 17:36:02 UTC 2023 , Edited by admin on Fri Dec 15 17:36:02 UTC 2023

PRIMARY

Related Record Type Details


					P5RI31WVDB

TRYPTOPHAN 5-HYDROXYLASE 1

TARGET -> INHIBITOR

Comments:

In vivo it is a potent and irreversible inhibitor of TPH (and PAH) that increases phenylalanine levels and rapidly depletes serotonin from the nervous system

Interaction Type:

IRREVERSIBLE INHIBITOR

Qualification:

IC50

Amount:


					SNM151OE2C

FENCLONINE, (S)-

ENANTIOMER -> RACEMATE


					4KHYO80GXC

CD98

TRANSPORTER -> SUBSTRATE


					RSS1JQ7MES

FENCLONINE, (R)-

ENANTIOMER -> RACEMATE

Related Record Type Details


					R5J7E3L9SP

ACTIVE MOIETY