LEVOFLOXACIN ANHYDROUS

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H20FN3O4
Molecular Weight	361.3675
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LEVOFLOXACIN ANHYDROUS

Structure Search

SMILES

C[C@H]1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2N4CCN(C)CC4

InChI

InChIKey=GSDSWSVVBLHKDQ-JTQLQIEISA-N

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H20FN3O4
Molecular Weight	361.3675
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:44:23 UTC 2023` Edited by `admin` on `Fri Dec 15 15:44:23 UTC 2023`
Record UNII	RIX4E89Y14
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LEVOFLOXACIN ANHYDROUS

Common Name

English

OFLOXACIN S-(-)-FORM [MI]

Common Name

English

OFLOXACIN S-(-)-FORM

Common Name

English

Levofloxacin [WHO-DD]

Common Name

English

NSC-758709

Code

English

levofloxacin [INN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

J01MA12

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

WHO-ATC

S01AX19

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

Code System Code Type Description

HSDB

8028

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

PRIMARY

SMS_ID

100000089067

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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EVMPD

SUB08471MIG

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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NSC

758709

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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FDA UNII

RIX4E89Y14

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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CHEBI

63598

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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DRUG BANK

DB01137

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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NCI_THESAURUS

C170539

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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CAS

100986-85-4

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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RXCUI

1546009

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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RxNorm

INN

6708

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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PUBCHEM

149096

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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EVMPD

SUB127353

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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MERCK INDEX

m8133

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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Merck Index

EPA CompTox

DTXSID0041060

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

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DAILYMED

RIX4E89Y14

Created by admin on Fri Dec 15 15:44:23 UTC 2023 , Edited by admin on Fri Dec 15 15:44:23 UTC 2023

PRIMARY

Related Record Type Details


					HTN0D03VRZ

LEVOFLOXACIN HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					B46KUN2O9L

MATE-2

TRANSPORTER -> INHIBITOR

Qualification:

IC50

Amount:


					3U6TN9Y2LD

MYCOPLASMA FERMENTANS

TARGET ORGANISM->INHIBITOR

Comments:

18 STRAINS; LESS THE 8 ng/mL for some strains; MIC range listed

Qualification:

MIC90

Amount:


					NHR291QA18

LEVOFLOXACIN LACTATE

SALT/SOLVATE -> PARENT


					1NF639GZUU

LEVOFLOXACIN SODIUM

SALT/SOLVATE -> PARENT


					6NP3XSMIP3

MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1

TRANSPORTER -> INHIBITOR

Qualification:

IC50

Amount:


					6GNT3Y5LMF

SALT/SOLVATE -> PARENT


					6GNT3Y5LMF

SUBSTANCE->BASIS OF STRENGTH


					6GNT3Y5LMF

SOLVATE->ANHYDROUS

Related Record Type Details


					88ZBA45NC8

N-DESMETHYL LEVOFLOXACIN

METABOLITE LESS ACTIVE -> PARENT

Comments:

Less than 5% of an administered dose was recovered in the urine as the desmethyl and N-oxide metabolites

Qualification:

URINE


					UE0E2O42UC

LEVOFLOXACIN N-OXIDE

METABOLITE LESS ACTIVE -> PARENT

Comments:

Less than 5% of an administered dose was recovered in the urine as the desmethyl and N-oxide metabolites

Qualification:

URINE


					UE0E2O42UC

LEVOFLOXACIN N-OXIDE

METABOLITE -> PARENT

Related Record Type Details


					RIX4E89Y14

LEVOFLOXACIN ANHYDROUS

ACTIVE MOIETY