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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H11F3N2O5
Molecular Weight 296.1999
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIFLURIDINE

SMILES

OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(C(=O)NC2=O)C(F)(F)F

InChI

InChIKey=VSQQQLOSPVPRAZ-RRKCRQDMSA-N
InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1

HIDE SMILES / InChI
Molecular Formula C10H11F3N2O5
Molecular Weight 296.1999
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:28:08 UTC 2023
Edited
by admin
on Sat Dec 16 16:28:08 UTC 2023
Record UNII
RMW9V5RW38
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRIFLURIDINE
INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
TRIFLURIDINE [USAN]
Common Name English
F3DTHD
Common Name English
TRIFLURIDINE [USP-RS]
Common Name English
TRIFLURIDINE [JAN]
Common Name English
5-TRIFLUOROMETHYL-2'-DEOXYURIDINE
Systematic Name English
TRIFLURIDINE [EP MONOGRAPH]
Common Name English
TRIFLURIDINE [ORANGE BOOK]
Common Name English
TRIFLURIDINE [USP MONOGRAPH]
Common Name English
TRIFLURIDINE [MI]
Common Name English
TRIFLUOROTHYMIDINE
Systematic Name English
TRIFLUOROMETHYLDEOXYURIDINE
Systematic Name English
trifluridine [INN]
Common Name English
2'-DEOXY-5-(TRIFLUOROMETHYL)URIDINE
Systematic Name English
THYMIDINE, .ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-
Systematic Name English
TRIFLURIDINE [VANDF]
Common Name English
TRIFLURIDINE COMPONENT OF LONSURF
Brand Name English
S-95005 COMPONENT TRIFLURIDINE
Common Name English
NSC-75520
Code English
TRIFLURIDINE [MART.]
Common Name English
NSC-529182
Code English
F3T
Common Name English
Trifluridine [WHO-DD]
Common Name English
VIROPTIC
Brand Name English
TAS-102 COMPONENT TRIFLURIDINE
Common Name English
Classification Tree Code System Code
NDF-RT N0000175595
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
NDF-RT N0000175459
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
NDF-RT N0000175459
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
WHO-VATC QS01AD02
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
WHO-ATC L01BC59
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
FDA ORPHAN DRUG 564116
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
NDF-RT N0000175466
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
NDF-RT N0000175459
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
WHO-ATC S01AD02
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
NCI_THESAURUS C1557
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
Code System Code Type Description
ECHA (EC/EINECS)
200-722-8
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
FDA UNII
RMW9V5RW38
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
MESH
D014271
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
RXCUI
10803
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY RxNorm
MESH
C448389
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
RS_ITEM_NUM
1686309
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
PUBCHEM
6256
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
CHEBI
75179
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
DRUG BANK
DB00432
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
WIKIPEDIA
TRIFLURIDINE
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
NSC
75520
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
EPA CompTox
DTXSID4046602
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
IUPHAR
8697
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
NCI_THESAURUS
C905
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
HSDB
8126
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
CAS
70-00-8
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
MERCK INDEX
m11125
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY Merck Index
SMS_ID
100000076935
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
EVMPD
SUB11291MIG
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
DAILYMED
RMW9V5RW38
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
INN
4146
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
NSC
529182
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
DRUG CENTRAL
2743
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
ChEMBL
CHEMBL1129
Created by admin on Sat Dec 16 16:28:09 UTC 2023 , Edited by admin on Sat Dec 16 16:28:09 UTC 2023
PRIMARY
Related Record Type Details
Structure of TRIFLURIDINE
EXCRETED UNCHANGED
URINE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
The in vitro protein binding in human plasma is greater than 96 % for trifluridine.
THYMIDYLATE SYNTHASE
TARGET -> INHIBITOR
Related Record Type Details
Structure of 5-(TRIFLUOROMETHYL)URACIL
METABOLITE INACTIVE -> PARENT
Structure of ISOOROTIC ACID
METABOLITE INACTIVE -> PARENT
Structure of 5-CARBOXY-2-DEOXYURIDINE
METABOLITE -> PARENT
Related Record Type Details
Structure of 5-CARBOXY-2-DEOXYURIDINE
IMPURITY -> PARENT
Related Record Type Details
Structure of TRIFLURIDINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Tmax PHARMACOKINETIC SINGLE DOSE ADMINISTRATION

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