TAZOBACTAM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H12N4O5S
Molecular Weight	300.291
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TAZOBACTAM

Structure Search

SMILES

[H][C@@]12CC(=O)N1[C@@H](C(O)=O)[C@](C)(CN3C=CN=N3)S2(=O)=O

InChI

InChIKey=LPQZKKCYTLCDGQ-WEDXCCLWSA-N

InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C10H12N4O5S
Molecular Weight	300.291
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:52:05 UTC 2023` Edited by `admin` on `Fri Dec 15 15:52:05 UTC 2023`
Record UNII	SE10G96M8W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TAZOBACTAM

Official Name

English

NSC-759887

Code

English

TAZOBACTAM [MI]

Common Name

English

tazobactam [INN]

Common Name

English

CL 298,741

Code

English

TAZOBACTAM [JAN]

Common Name

English

TAZOBACTAM [USP IMPURITY]

Common Name

English

YTR-830H

Code

English

Tazobactam [WHO-DD]

Common Name

English

TAZOBACTAM [USP MONOGRAPH]

Common Name

English

TAZOBACTAM [USAN]

Common Name

English

TAZOBACTAM [USP-RS]

Common Name

English

Classification Tree Code System Code

LIVERTOX

NBK548825

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

NDF-RT

N0000175930

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

NDF-RT

N0000000202

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

NCI_THESAURUS

C1500

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

WHO-ATC

J01CG02

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

WHO-ATC

J01DH51

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

WHO-VATC

QJ01CG02

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

Code System Code Type Description

RXCUI

37617

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

RxNorm

FDA UNII

SE10G96M8W

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

CHEBI

9421

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

NCI_THESAURUS

C62079

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

CAS

89786-04-9

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

WIKIPEDIA

TAZOBACTAM

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

DRUG BANK

DB01606

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

LACTMED

Ceftolozane and Tazobactam

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

INN

6340

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

DAILYMED

SE10G96M8W

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

USAN

AA-6

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

MERCK INDEX

m10490

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

Merck Index

MESH

C043265

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

LACTMED

Piperacillin and Tazobactam

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

PUBCHEM

123630

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

EVMPD

SUB10849MIG

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

EPA CompTox

DTXSID8023634

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

ChEMBL

CHEMBL404

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

NSC

759887

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

DRUG CENTRAL

2572

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

SMS_ID

100000091983

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

RS_ITEM_NUM

1643383

Created by admin on Fri Dec 15 15:52:05 UTC 2023 , Edited by admin on Fri Dec 15 15:52:05 UTC 2023

PRIMARY

Related Record Type Details


					2YRJ6OXK1M

TAZOBACTAM HEMIHYDRATE

SOLVATE->ANHYDROUS


					SE10G96M8W

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:


					UXA545ABTT

TAZOBACTAM SODIUM

SALT/SOLVATE -> PARENT


					SE10G96M8W

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					2YRJ6OXK1M

TAZOBACTAM HEMIHYDRATE

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Comments:

The protein binding of either piperacillin or tazobactam is unaffected by the presence of the other compound.

Related Record Type Details


					76FCB4Z98Z

2-AMINO-3-METHYL-3-SULFINO-4-(1H-1,2,3-TRIAZOL-1-YL)BUTYRIC ACID, (2S,3S)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					SE10G96M8W

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC