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Details

Stereochemistry RACEMIC
Molecular Formula 2C15H25NO3.C4H6O4
Molecular Weight 652.8158
Optical Activity ( + / - )
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METOPROLOL SUCCINATE

SMILES

OC(=O)CCC(O)=O.COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC2=CC=C(OCC(O)CNC(C)C)C=C2

InChI

InChIKey=RGHAZVBIOOEVQX-UHFFFAOYSA-N
InChI=1S/2C15H25NO3.C4H6O4/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-3(6)1-2-4(7)8/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

HIDE SMILES / InChI
Molecular Formula C4H6O4
Molecular Weight 118.088
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C15H25NO3
Molecular Weight 267.3639
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:51:12 UTC 2023
Edited
by admin
on Fri Dec 15 15:51:12 UTC 2023
Record UNII
TH25PD4CCB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METOPROLOL SUCCINATE
EP   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN  
Official Name English
2-PROPANOL, 1-(4-(2-METHOXYETHYL)PHENOXY)-3-((1-METHYLETHYL)AMINO)-, (±)-, BUTANEDIOATE (2:1) (SALT)
Common Name English
METOPROLOL SUCCINATE [USP-RS]
Common Name English
METOPROLOL SUCCINATE [VANDF]
Common Name English
TOPROL-XL
Brand Name English
METOPROLOL SUCCINATE [MART.]
Common Name English
H 93/26 SUCCINATE
Code English
(±)-1-(ISOPROPYLAMINO)-3-(P-(2-METHOXYETHYL)PHENOXY)-2-PROPANOL SUCCINATE (2:1) (SALT)
Common Name English
TOPROL
Brand Name English
METOPROLOL SUCCINATE [EP IMPURITY]
Common Name English
SELOZOK
Brand Name English
METOPROLOL SUCCINATE [USP MONOGRAPH]
Common Name English
Metoprolol succinate [WHO-DD]
Common Name English
METOPROLOL SUCCINATE [EP MONOGRAPH]
Common Name English
DUTOPROL COMPONENT METOPROLOL SUCCINATE
Common Name English
SELOKEN-ZOK
Brand Name English
METOPROLOL SUCCINATE COMPONENT OF DUTOPROL
Common Name English
METOPROLOL SUCCINATE [USAN]
Common Name English
METOPROLOL SUCCINATE [MI]
Common Name English
METOPROLOL HEMISUCCINATE
Common Name English
METOPROLOL SUCCINATE [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29576
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
Code System Code Type Description
FDA UNII
TH25PD4CCB
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
SMS_ID
100000091368
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
RS_ITEM_NUM
1441298
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
CAS
98418-47-4
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
ChEMBL
CHEMBL13
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
CAS
123245-49-8
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
NON-SPECIFIC STOICHIOMETRY
EPA CompTox
DTXSID9048726
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
DAILYMED
TH25PD4CCB
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
MESH
C402833
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
EVMPD
SUB03274MIG
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
RXCUI
221124
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C29254
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
MERCK INDEX
m7498
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY Merck Index
PUBCHEM
62937
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
USAN
DD-24
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
DRUG BANK
DBSALT000863
Created by admin on Fri Dec 15 15:51:12 UTC 2023 , Edited by admin on Fri Dec 15 15:51:12 UTC 2023
PRIMARY
Related Record Type Details
Structure of METOPROLOL SUCCINATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
Structure of METOPROLOL SUCCINATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of METOPROLOL
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of O-DEMETHYLMETOPROLOL
IMPURITY -> PARENT
USP
Structure of H-93/82
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of 4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)BENZALDEHYDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 1-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)-3-(4-(2-METHOXYETHYL)PHENOXY)PROPAN-2-OL
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of N,N-BIS(2-HYDROXY-3-(4-(2-METHOXYETHYL)PHENOXY)PROPYL)ISOPROPYLAMINE
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of 1,3-BIS((1-METHYLETHYL)AMINO)PROPAN-2-OL
IMPURITY -> PARENT
any impurity: any spot, apart from the principal spot, is not more intense than the spot in the chromatogram obtained with the reference solution (0.2 per cent)
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of 4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)BENZALDEHYDE
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of TYROSOL
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of 3-ISOPROPYLAMINO-1,2-PROPANEDIOL
IMPURITY -> PARENT
any impurity: any spot, apart from the principal spot, is not more intense than the spot in the chromatogram obtained with the reference solution (0.2 per cent)
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of 1-ETHYLAMINO-3-(4-(2-METHOXYETHYL)PHENOXY)PROPAN-2-OL
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of H-9/64
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of 4-(2-METHOXYETHYL)PHENOL
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of N,N-BIS(2-HYDROXY-3-(4-(2-METHOXYETHYL)PHENOXY)PROPYL)ISOPROPYLAMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
EP
Structure of 1-CHLORO-2-HYDROXY-3-(4-(2-METHOXYETHYL)PHENOXY)-PROPANE
IMPURITY -> PARENT
USP
Structure of ORTHO-METOPROLOL
IMPURITY -> PARENT
UNSPECIFIED
USP
Structure of 1-ETHYLAMINO-3-(4-(2-METHOXYETHYL)PHENOXY)PROPAN-2-OL
IMPURITY -> PARENT
EP
Related Record Type Details
Structure of METOPROLOL
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Tmax PHARMACOKINETIC
ORAL BIOAVAILABILITY PHARMACOKINETIC EXTENDED-RELEASE, TABLET
PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
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