MEFLOQUINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H16F6N2O
Molecular Weight	378.3122
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MEFLOQUINE

Structure Search

SMILES

[H][C@@]1(CCCCN1)[C@@H](O)C2=C3C=CC=C(C3=NC(=C2)C(F)(F)F)C(F)(F)F

InChI

InChIKey=XEEQGYMUWCZPDN-DOMZBBRYSA-N

InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H16F6N2O
Molecular Weight	378.3122
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:49:07 UTC 2023` Edited by `admin` on `Sat Dec 16 17:49:07 UTC 2023`
Record UNII	TML814419R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEFLOQUINE

Official Name

English

mefloquine [INN]

Common Name

English

(DL-ERYTHRO-.ALPHA.-2-PIPERIDYL-2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINEMETHANOL

Common Name

English

MEFLOQUINE [MI]

Common Name

English

RO-215998

Code

English

WR 142,490

Code

English

MEFLOQUINE [USAN]

Common Name

English

4-QUINOLINEMETHANOL, .ALPHA.-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (R*,S*)-(±)-

Common Name

English

MEFLOQUINE [VANDF]

Common Name

English

NSC-758233

Code

English

RO 21-5998

Code

English

Mefloquine [WHO-DD]

Common Name

English

MEFLOQUINE [HSDB]

Common Name

English

Classification Tree Code System Code

WHO-ATC

P01BC02

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

WHO-ATC

P01BF02

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

NDF-RT

N0000175482

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.5.3.2

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

LIVERTOX

NBK548541

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

NCI_THESAURUS

C271

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.5.3.1

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

Code System Code Type Description

WIKIPEDIA

MEFLOQUINE

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

MESH

D015767

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

DRUG BANK

DB00358

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

EPA CompTox

DTXSID4037168

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

FDA UNII

TML814419R

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

DRUG CENTRAL

1665

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

ChEMBL

CHEMBL416956

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

RXCUI

6694

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

RxNorm

CAS

53230-10-7

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

DAILYMED

TML814419R

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

SMS_ID

100000091787

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

IUPHAR

4252

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

NCI_THESAURUS

C61827

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

NSC

758233

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

CHEBI

63609

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

EVMPD

SUB08709MIG

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

PUBCHEM

40692

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

HSDB

6853

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

MERCK INDEX

m7142

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

Merck Index

LACTMED

Mefloquine

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

INN

3777

Created by admin on Sat Dec 16 17:49:08 UTC 2023 , Edited by admin on Sat Dec 16 17:49:08 UTC 2023

PRIMARY

Related Record Type Details


					642Y4F6L0K

MEFLOQUINE MESYLATE

SALT/SOLVATE -> PARENT


					Y6M7C81O5B

OFF-TARGET->INHIBITOR

Amount:


					482M00274D

OCT-2

TRANSPORTER -> INHIBITOR

Related Record Type Details


					462L37KS1K

CARBOXYMEFLOQUINE

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR

Qualification:

PLASMA


					982JUO87NM

METABOLITE -> PARENT

Interaction Type:

MINOR

Related Record Type Details


					TML814419R

ACTIVE MOIETY