METOLAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H16ClN3O3S
Molecular Weight	365.835
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METOLAZONE

Structure Search

SMILES

CC1NC2=CC(Cl)=C(C=C2C(=O)N1C3=C(C)C=CC=C3)S(N)(=O)=O

InChI

InChIKey=AQCHWTWZEMGIFD-UHFFFAOYSA-N

InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)

HIDE SMILES / InChI

Molecular Formula	C16H16ClN3O3S
Molecular Weight	365.835
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:43:13 UTC 2023` Edited by `admin` on `Fri Dec 15 15:43:13 UTC 2023`
Record UNII	TZ7V40X7VX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

METOLAZONE

Official Name

English

SR-720-22

Code

English

METOLAZONE [VANDF]

Common Name

English

OLDREN

Brand Name

English

7-CHLORO-1,2,3,4-TETRAHYDRO-2-METHYL-4-OXO-3-O-TOLYL-6-QUINAZOLINESULFONAMIDE

Common Name

English

METOZALONE

Common Name

English

METOLAZONE [USP-RS]

Common Name

English

METOLAZONE [EP MONOGRAPH]

Common Name

English

METOLAZONE [USAN]

Common Name

English

METOLAZONE [ORANGE BOOK]

Common Name

English

MYKROX

Brand Name

English

METOLAZONE [EP IMPURITY]

Common Name

English

Metolazone [WHO-DD]

Common Name

English

METOLAZONE [JAN]

Common Name

English

METOLAZONE [USP MONOGRAPH]

Common Name

English

ZAROXOLYN

Brand Name

English

METOLAZONE [MART.]

Common Name

English

METENIX

Brand Name

English

NORMELAN

Brand Name

English

NSC-759581

Code

English

metolazone [INN]

Common Name

English

6-QUINAZOLINESULFONAMIDE, 7-CHLORO-1,2,3,4-TETRAHYDRO-2-METHYL-3-(2-METHYLPHENYL)-4-OXO-

Systematic Name

English

SR 720-22

Code

English

METOLAZONE [HSDB]

Common Name

English

METOLAZONE [MI]

Common Name

English

METAZOLINE

Common Name

English

DIULO

Brand Name

English

Classification Tree Code System Code

LIVERTOX

630

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

WHO-ATC

C03BA08

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

WHO-VATC

QC03BA08

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

NDF-RT

N0000175359

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

WHO-ATC

C03EA12

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

NCI_THESAURUS

C49185

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

WHO-VATC

QC03EA12

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

NDF-RT

N0000175420

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

Code System Code Type Description

SMS_ID

100000080921

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

WIKIPEDIA

METOLAZONE

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

EVMPD

SUB08906MIG

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

ChEMBL

CHEMBL878

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

EPA CompTox

DTXSID6045167

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

FDA UNII

TZ7V40X7VX

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

HSDB

3367

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

DRUG CENTRAL

1783

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

LACTMED

Metolazone

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

INN

2627

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

CHEBI

64354

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

ECHA (EC/EINECS)

241-539-3

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

DAILYMED

TZ7V40X7VX

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

IUPHAR

4838

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

CAS

17560-51-9

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

NSC

759581

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

NCI_THESAURUS

C650

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

MERCK INDEX

m7494

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

Merck Index

RS_ITEM_NUM

1441200

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

PUBCHEM

4170

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

RXCUI

6916

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

RxNorm

DRUG BANK

DB00524

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

MESH

D008788

Created by admin on Fri Dec 15 15:43:13 UTC 2023 , Edited by admin on Fri Dec 15 15:43:13 UTC 2023

PRIMARY

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					TZ7V40X7VX

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (UV)

Qualification:

USP

Amount:


					TZ7V40X7VX

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

EP

Amount:


					NM7V2Y3G0U

METOLAZONE, (+)-

ENANTIOMER -> RACEMATE


					Q3AVC19UXB

METOLAZONE SODIUM

SALT/SOLVATE -> PARENT


					NN9U607695

METOLAZONE, (-)-

ENANTIOMER -> RACEMATE

Related Record Type Details


					883J1AF03V

IMPURITY -> PARENT

Interaction Type:

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Qualification:

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Amount:


					HC03B6WQA9

DESMETHYL METOLAZONE

IMPURITY -> PARENT

Interaction Type:

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Qualification:

EP

Amount:


					ET594CS2LG

7-Chloro-6-sulfamoylisatoic anhydride

IMPURITY -> PARENT

Amount:


					74G6NBS2I7

DIDEHYDROMETOLAZONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					Q1M5J89G86

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					U9363D8R2T

2-Amino-4-chloro-5-sulfamoyl-N-(o-tolyl)benzamide

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

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					TZ7V40X7VX

ACTIVE MOIETY