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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H24FN3O4
Molecular Weight 401.4314
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MOXIFLOXACIN

SMILES

[H][C@]12CN(C[C@@]1([H])NCCC2)C3=C(OC)C4=C(C=C3F)C(=O)C(=CN4C5CC5)C(O)=O

InChI

InChIKey=FABPRXSRWADJSP-MEDUHNTESA-N
InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1

HIDE SMILES / InChI
Molecular Formula C21H24FN3O4
Molecular Weight 401.4314
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:55:37 UTC 2023
Edited
by admin
on Sat Dec 16 16:55:37 UTC 2023
Record UNII
U188XYD42P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MOXIFLOXACIN
INN   MI   VANDF   WHO-DD  
INN  
Official Name English
moxifloxacin [INN]
Common Name English
AVELOX IV
Brand Name English
1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-((4AS,7AS)-OCTAHYDRO-6H-PYRROLO(3,4-B)PYRIDIN-6-YL)-4-OXO-3-QUINOLINECARBOXYLIC ACID
Common Name English
Moxifloxacin [WHO-DD]
Common Name English
MOXIFLOXACIN [VANDF]
Common Name English
ZIMOXIN
Brand Name English
MOXIFLOXACIN [MI]
Common Name English
Classification Tree Code System Code
WHO-ATC S01AX22
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
WHO-ATC J01MA14
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
NCI_THESAURUS C795
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
NDF-RT N0000175937
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
WHO-VATC QS01AE07
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
WHO-VATC QJ01MA14
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
LIVERTOX NBK548166
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
WHO-ATC S01AE07
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
NDF-RT N0000007606
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
Code System Code Type Description
INN
7659
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
HSDB
8026
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
NCI_THESAURUS
C62052
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
WIKIPEDIA
MOXIFLOXACIN
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
CHEBI
63611
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
DAILYMED
U188XYD42P
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
LACTMED
Moxifloxacin
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
PUBCHEM
152946
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
CAS
151096-09-2
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
EVMPD
SUB09086MIG
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
ChEMBL
CHEMBL32
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
MERCK INDEX
m7647
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY Merck Index
RXCUI
139462
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY RxNorm
FDA UNII
U188XYD42P
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
SMS_ID
100000080618
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
DRUG BANK
DB00218
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
CAS
354812-41-2
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
NON-SPECIFIC STEREOCHEMISTRY
MESH
C104727
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
DRUG CENTRAL
1854
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
EPA CompTox
DTXSID3048491
Created by admin on Sat Dec 16 16:55:39 UTC 2023 , Edited by admin on Sat Dec 16 16:55:39 UTC 2023
PRIMARY
Related Record Type Details
STREPTOCOCCUS VIRIDANS GROUP
TARGET ORGANISM->INHIBITOR
STAPHYLOCOCCUS AUREUS
TARGET ORGANISM->INHIBITOR
CHLAMYDIA TRACHOMATIS
TARGET ORGANISM->INHIBITOR
Structure of DECARBOXY MOXIFLOXACIN
DEGRADENT -> PARENT
HAEMOPHILUS INFLUENZAE
TARGET ORGANISM->INHIBITOR
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
STAPHYLOCOCCUS EPIDERMIDIS
TARGET ORGANISM->INHIBITOR
MICROCOCCUS LUTEUS
TARGET ORGANISM->INHIBITOR
Structure of MOXIFLOXACIN HYDROCHLORIDE
SALT/SOLVATE -> PARENT
STAPHYLOCOCCUS HAEMOLYTICUS
TARGET ORGANISM->INHIBITOR
STREPTOCOCCUS PNEUMONIAE
TARGET ORGANISM->INHIBITOR
BACTERIAL DNA GYRASE
TARGET -> INHIBITOR
Structure of MOXIFLOXACIN HYDROCHLORIDE MONOHYDRATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of MOXIFLOXACIN ACYL-.BETA.-D-GLUCURONIDE
METABOLITE INACTIVE -> PARENT
MINOR
PLASMA; URINE
Structure of MOXIFLOXACIN 1-SULFATE
METABOLITE INACTIVE -> PARENT
MAJOR
FECAL; PLASMA
Related Record Type Details
Structure of DECARBOXY MOXIFLOXACIN
IMPURITY -> PARENT
Structure of MOXIFLOXACIN DIFLUORO METHOXY ETHYL ESTER
IMPURITY -> PARENT
Related Record Type Details
Structure of MOXIFLOXACIN
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MIC BIOLOGICAL SUSCEPTIBILITY: RESISTANT

PATHOGEN:l E. FAECALIS, S. PNEUMONIAE, STREPTOCOCCUS SPECIES

MIC BIOLOGICAL SUSCEPTIBILITY: SUSCEPTIBLE

PATHOGEN:l E. FAECALIS, H. INFLUENZAE, H. PARAINFLUENZAE, S. PNEUMONIAE, STREPTOCOCCUS SPECIES

Biological Half-life PHARMACOKINETIC DOSE FREQUENCY: SINGLE DOSE

ROUTE OF ADMINISTRATION: IV

MIC BIOLOGICAL SUSCEPTIBILITY: INTERMEDIATE

PATHOGEN: S. AUREUS

ORAL BIOAVAILABILITY PHARMACOKINETIC
MIC BIOLOGICAL SUSCEPTIBILITY: SUSCEPTIBLE

PATHOGEN: S. AUREUS

MIC BIOLOGICAL SUSCEPTIBILITY: RESISTANT

PATHOGEN: ENTEROBACTERIACAE, ANEROBIC BACTERIA

Volume of Distribution PHARMACOKINETIC
MIC BIOLOGICAL SUSCEPTIBILITY: SUSCEPTIBLE

PATHOGEN: ENTEROBACTERIACAE, ANAEROBIC BACTERIA

MIC BIOLOGICAL PATHOGEN: ENTEROBACTERIACAE, ANEROBIC BACTERIA

SUSCEPTIBILITY: INTERMEDIATE

MIC BIOLOGICAL SUSCEPTIBILITY: INTERMEDIATE

PATHOGEN:l E. FAECALIS, S. PNEUMONIAE, STREPTOCOCCUS SPECIES

Biological Half-life PHARMACOKINETIC DOSE FREQUENCY: SINGLE DOSE

ROUTE OF ADMINISTRATION: ORAL

MIC BIOLOGICAL PATHOGEN: Y. PESTIS

SUSCEPTIBILITY: SUSCEPTIBLE

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