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Details

Stereochemistry RACEMIC
Molecular Formula C10H19O6PS2
Molecular Weight 330.358
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MALATHION

SMILES

CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC

InChI

InChIKey=JXSJBGJIGXNWCI-UHFFFAOYSA-N
InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3

HIDE SMILES / InChI
Molecular Formula C10H19O6PS2
Molecular Weight 330.358
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:22:49 UTC 2023
Edited
by admin
on Fri Dec 15 18:22:49 UTC 2023
Record UNII
U5N7SU872W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MALATHION
EP   HSDB   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD  
Common Name English
MALATHION [MART.]
Common Name English
ENT-17034
Code English
MALATHION [VANDF]
Common Name English
MALATHION [ORANGE BOOK]
Common Name English
MALATHION [MI]
Common Name English
MALATHION [IARC]
Common Name English
Malathion [WHO-DD]
Common Name English
MALATHION [EP MONOGRAPH]
Common Name English
DIETHYL 2-((DIMETHOXYPHOSPHINOTHIOYL)THIO)BUTANEDIOATE
Systematic Name English
DIETHYL (±)-MERCAPTOSUCCINATE, S-ESTER WITH O,O-DIMETHYL PHOSPHORODITHIOATE
Common Name English
MALATHION [USP MONOGRAPH]
Common Name English
8059HC
Code English
BUTANEDIOIC ACID, ((DIMETHOXYPHOSPHINOTHIOYL)-THIO)-, DIETHYL ESTER, (±)-
Common Name English
DIETHYL (DIMETHOXYPHOSPHINOTHIOYLTHIO)SUCCINATE
Systematic Name English
MALATHION [HSDB]
Common Name English
ENT 17,034
Code English
NSC-6524
Code English
BUTANEDIOIC ACID, ((DIMETHOXYPHOSPHINOTHIOYL)THIO)-, DIETHYL ESTER
Common Name English
SUCCINIC ACID, MERCAPTO-, DIETHYL ESTER, S-ESTER WITH O,O-DIMETHYLPHOSPHORODITHIOATE
Common Name English
MALATHION [USP-RS]
Common Name English
OVIDE
Code English
Classification Tree Code System Code
NDF-RT N0000175723
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
NCI_THESAURUS C29727
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
EPA PESTICIDE CODE 57701
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
WHO-ATC P03AX03
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
WHO-VATC QP53AF12
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
NDF-RT N0000000177
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
Code System Code Type Description
NSC
6524
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
CAS
121-75-5
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
ChEMBL
CHEMBL1200468
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
HSDB
665
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
ALANWOOD
malathion
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
EVMPD
SUB14453MIG
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
EPA CompTox
DTXSID4020791
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
LACTMED
Malathion
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
ECHA (EC/EINECS)
204-497-7
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
CHEBI
6651
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
NCI_THESAURUS
C47593
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
MERCK INDEX
m7034
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY Merck Index
RXCUI
6606
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY RxNorm
DAILYMED
U5N7SU872W
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
SMS_ID
100000076812
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
PUBCHEM
4004
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
DRUG BANK
DB00772
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
FDA UNII
U5N7SU872W
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
RS_ITEM_NUM
1374408
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
WIKIPEDIA
MALATHION
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
MESH
D008294
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
DRUG CENTRAL
1626
Created by admin on Fri Dec 15 18:22:49 UTC 2023 , Edited by admin on Fri Dec 15 18:22:49 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 1A1
METABOLIC ENZYME -> INHIBITOR
Malathion inhibited CYP1A1/2 activities more than 90%.
CYTOCHROME P450 1A2
METABOLIC ENZYME -> INHIBITOR
Malathion inhibited CYP1A1/2 activities more than 90%.
CYTOCHROME P450 2C8
METABOLIC ENZYME -> INHIBITOR
Human hepatic CYP2C8 activities after incubation with different pesticides showed that CYP2C8 activities were inhibited extensively by malathion (100,90%).
CYTOCHROME P450 2A6
METABOLIC ENZYME -> INHIBITOR
Extensive inhibitions of CYP2A6-associated activity (94–98%) were observed with malathion
CYTOCHROME P450 2C9
METABOLIC ENZYME -> INHIBITOR
CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides malathion
CYTOCHROME P450 2B6
METABOLIC ENZYME -> INHIBITOR
Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Malathion and phenthoate resulted in 91% inhibition.
Related Record Type Details
Structure of MALAOXON
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BUTANEDIOIC ACID, 2-((DIMETHOXYPHOSPHINOTHIOYL)THIO)-, 4-ETHYL 1-METHYL ESTER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ISOMALATHION
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of MALATHION
ACTIVE MOIETY
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NCATS
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