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Details

Stereochemistry ACHIRAL
Molecular Formula C15H13ClFNO2
Molecular Weight 293.721
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LUMIRACOXIB

SMILES

CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(CC(O)=O)=C1

InChI

InChIKey=KHPKQFYUPIUARC-UHFFFAOYSA-N
InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20)

HIDE SMILES / InChI
Molecular Formula C15H13ClFNO2
Molecular Weight 293.721
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:22:00 UTC 2023
Edited
by admin
on Sat Dec 16 16:22:00 UTC 2023
Record UNII
V91T9204HU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LUMIRACOXIB
INN   MART.   MI   USAN   WHO-DD  
USAN   INN  
Official Name English
COX-189
Code English
2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl]acetic acid
Common Name English
LUMIRACOXIB [MART.]
Common Name English
PREXIGE
Brand Name English
LUMIRACOXIB [USAN]
Common Name English
Lumiracoxib [WHO-DD]
Common Name English
lumiracoxib [INN]
Common Name English
BENZENEACETIC ACID, 2-((2-CHLORO-6-FLUOROPHENYL)AMINO)-5-METHYL-
Common Name English
LUMIRACOXIB [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1323
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
WHO-VATC QM01AH06
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
WHO-ATC M01AH06
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
Code System Code Type Description
ChEMBL
CHEMBL404108
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
DRUG CENTRAL
1618
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
MESH
C473384
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
WIKIPEDIA
LUMIRACOXIB
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
PUBCHEM
151166
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
INN
8151
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
EPA CompTox
DTXSID9049035
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
SMS_ID
100000084778
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
MERCK INDEX
m6931
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY Merck Index
USAN
OO-27
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
DRUG BANK
DB01283
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
CHEBI
73044
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
FDA UNII
V91T9204HU
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
EVMPD
SUB21406
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
CAS
220991-20-8
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
IUPHAR
2897
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
NCI_THESAURUS
C66041
Created by admin on Sat Dec 16 16:22:02 UTC 2023 , Edited by admin on Sat Dec 16 16:22:02 UTC 2023
PRIMARY
Related Record Type Details
Structure of LUMIRACOXIB
EXCRETED UNCHANGED
FECAL
Structure of LUMIRACOXIB
EXCRETED UNCHANGED
URINE
COX-2
TARGET -> INHIBITOR
CYTOCHROME P450 2C9
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
Structure of LUMIRACOXIB-1-O-GLUCURONIDE
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Structure of 4'-HYDROXY-LUMIRACOXIB
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Structure of 5-CARBOXY LUMIRACOXIB LACTAM
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Structure of LUMIRACOXIB LACTAM 4'-O-GLUCURONIDE
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Structure of 5-CARBOXY-4'-HYDROXYLUMIRACOXIB
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Structure of 5-CARBOXY-4'-HYDROXYLUMIRACOXIB LACTAM
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METABOLITE -> PARENT
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Structure of 5-HYDROXYMETHYL LUMIRACOXIB
METABOLITE -> PARENT
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Structure of 5-CARBOXY-4'-HYDROXYLUMIRACOXIB
METABOLITE ACTIVE -> PARENT
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Structure of 5-CARBOXY LUMIRACOXIB
METABOLITE -> PARENT
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Structure of 5-CARBOXY LUMIRACOXIB LACTAM
METABOLITE -> PARENT
MINOR
PLASMA
Structure of 5-CARBOXY LUMIRACOXIB
METABOLITE -> PARENT
MAJOR
PLASMA
Related Record Type Details
Structure of LUMIRACOXIB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC ORAL ADMINISTRATION

SINGLE DOSE

Tmax PHARMACOKINETIC SINGLE DOSE

ORAL ADMINISTRATION

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