OLODATEROL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H26N2O5
Molecular Weight	386.4415
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OLODATEROL

Structure Search

SMILES

COC1=CC=C(CC(C)(C)NC[C@H](O)C2=CC(O)=CC3=C2OCC(=O)N3)C=C1

InChI

InChIKey=COUYJEVMBVSIHV-SFHVURJKSA-N

InChI=1S/C21H26N2O5/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26)/t18-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H26N2O5
Molecular Weight	386.4415
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:01:34 UTC 2023` Edited by `admin` on `Fri Dec 15 16:01:34 UTC 2023`
Record UNII	VD2YSN1AFD
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OLODATEROL

Official Name

English

Olodaterol [WHO-DD]

Common Name

English

OLODATEROL HYDROCHLORIDE [JAN]

Common Name

English

BI 1744

Code

English

OLODATEROL [VANDF]

Common Name

English

2H-1,4-BENZOXAZIN-3(4H)-ONE, 6-HYDROXY-8-((1R)-1-HYDROXY-2-((2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYL)AMINO)ETHYL)-

Systematic Name

English

6-HYDROXY-8-((1R)-1-HYDROXY-2-((1-(4-METHOXYPHENYL)-2-METHYLPROPAN-2-YL)AMINO)ETHYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE

Systematic Name

English

6-HYDROXY-8-((1R)-1-HYDROXY-2-((2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYL)AMINO)ETHYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE

Systematic Name

English

olodaterol [INN]

Common Name

English

BI-1744

Code

English

OLODATEROL [MI]

Common Name

English

OLODATEROL [USAN]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175779

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

WHO-ATC

R03AL06

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

WHO-ATC

R03AC19

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

WHO-VATC

QR03AC19

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

Code System Code Type Description

INN

9174

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

RXCUI

1546059

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

RxNorm

IUPHAR

7543

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

DRUG BANK

DB09080

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

CAS

868049-49-4

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

EPA CompTox

DTXSID601024792

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

SMS_ID

100000128703

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

ChEMBL

CHEMBL605846

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

MERCK INDEX

m11957

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

MESH

C549647

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

FDA UNII

VD2YSN1AFD

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

USAN

YY-80

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

WIKIPEDIA

Olodaterol

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

DAILYMED

VD2YSN1AFD

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

CHEBI

82700

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

NCI_THESAURUS

C170249

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

DRUG CENTRAL

4814

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

PUBCHEM

11504295

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

LACTMED

Olodaterol

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

EVMPD

SUB36104

Created by admin on Fri Dec 15 16:01:34 UTC 2023 , Edited by admin on Fri Dec 15 16:01:34 UTC 2023

PRIMARY

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PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					0M77ZW789J

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

METABOLIC ENZYME -> SUBSTRATE


					65R445W3V9

OLODATEROL HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					0RFO7VC96N

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A1

METABOLIC ENZYME -> SUBSTRATE


					HWT82Q8F2V

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A7

METABOLIC ENZYME -> SUBSTRATE


					VZX139UJO5

BETA-2 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Interaction Type:

SHORT-ACTING

Amount:


					L0423Z5LDW

CYTOCHROME P450 2C8

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR


					3318TFY23Q

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9

METABOLIC ENZYME -> SUBSTRATE


					B6QJ6CAW2G

Olodaterol, (S)-

ENANTIOMER -> ENANTIOMER

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> SUBSTRATE

Related Record Type Details


					NC8KNH6SJC

(2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-((8-((1R)-1-HYDROXY-2-((2-(4-METHOXYPHENYL)-1,1-DIMETHYL-ETHYL)AMINO)ETHYL)-3-OXO-4H-1,4-BENZOXAZIN-6-YL)OXY)TETRAHYDROPYRAN-2-CARBOXYLIC ACID

METABOLITE -> PARENT


					2NL5LG9LU4

(4-(2-(((2R)-2-HYDROXY-2-(6-HYDROXY-3-OXO-4H-1,4-BENZOXAZIN-8-YL)ETHYL)AMINO)-2-METHYL-PROPYL)PHENYL) HYDROGEN SULFATE

METABOLITE -> PARENT


					E62D9WW7KR

(2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-((8-((1R)-1-HYDROXY-2-((2-(4-HYDROXYPHENYL)-1,1-DIMETHYL-ETHYL)AMINO)ETHYL)-3-OXO-4H-1,4-BENZOXAZIN-6-YL)OXY)TETRAHYDROPYRAN-2-CARBOXYLIC ACID

METABOLITE -> PARENT


					XIM8YCX9C1

SOM-1522

METABOLITE ACTIVE -> PARENT

Interaction Type:

MAJOR

Qualification:

FECAL

Amount:


					KKZ589W9XR

(2S,3S,4S,5R)-3,4,5-TRIHYDROXY-6-((1R)-1-(6-HYDROXY-3-OXO-4H-1,4-BENZOXAZIN-8-YL)-2-((2-(4-METHOXYPHENYL)-1,1-DIMETHYL-ETHYL)AMINO)ETHOXY)TETRAHYDROPYRAN-2-CARBOXYLIC ACID

METABOLITE -> PARENT

Related Record Type Details


					VD2YSN1AFD

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				INHALED ADMINISTRATION