U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C21H30O5
Molecular Weight 362.4599
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROCORTISONE

SMILES

[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)CC[C@]34C

InChI

InChIKey=JYGXADMDTFJGBT-VWUMJDOOSA-N
InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

HIDE SMILES / InChI
Molecular Formula C21H30O5
Molecular Weight 362.4599
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 7 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:16:08 UTC 2023
Edited
by admin
on Fri Dec 15 15:16:08 UTC 2023
Record UNII
WI4X0X7BPJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HYDROCORTISONE
EP   GREEN BOOK   HSDB   II   INN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD  
INN  
Official Name English
HYDROCORTISONE [ORANGE BOOK]
Common Name English
HYDROCORTISONE [WHO-IP]
Common Name English
HYDROCORTISONE COMPONENT OF CALMURID HC
Common Name English
HYDROCORTISONE [USP-RS]
Common Name English
PROCTOCORT
Brand Name English
ANUSOL HC
Brand Name English
GLYCORT
Brand Name English
HYDROCORTISONE COMPONENT OF PYOCIDIN
Common Name English
CORTENEMA
Brand Name English
HYDROCORTISONE [II]
Common Name English
OTOCORT COMPONENT HYDROCORTISONE
Common Name English
HYDROCORTISONE COMPONENT OF OTOBIOTIC
Common Name English
TEXACORT
Brand Name English
PLENADREN
Brand Name English
Hydrocortisone [WHO-DD]
Common Name English
HYDROCORTISONE COMPONENT OF OTICAIR
Common Name English
CORTEF
Brand Name English
HYDROCORTISONE [VANDF]
Common Name English
Cortisol
Common Name English
AEROSEB-HC
Brand Name English
PREGN-4-ENE-3,20-DIONE, 11,17,21-TRIHYDROXY-, (11.BETA.)-
Systematic Name English
NOGENIC HC
Brand Name English
HYDROCORTISONE [MART.]
Common Name English
STIE-CORT
Brand Name English
EPICORT
Brand Name English
OTOBIONE COMPONENT HYDROCORTISONE
Common Name English
HYDROCORTISONE [USP MONOGRAPH]
Common Name English
HYDROCORTISONE [JAN]
Common Name English
HYDROCORTISONE [MI]
Common Name English
HYDROCORTONE
Brand Name English
HYDROCORTISONE [GREEN BOOK]
Common Name English
COLOCORT
Brand Name English
HYDROCORTISONE COMPONENT OF OTOBIONE
Common Name English
PEDIOTIC COMPONENT HYDROCORTISONE
Common Name English
CALMURID HC COMPONENT HYDROCORTISONE
Common Name English
SYNACORT
Brand Name English
NSC-10483
Code English
CORTRIL
Brand Name English
FLEXICORT
Code English
PYOCIDIN COMPONENT HYDROCORTISONE
Common Name English
BETA-HC
Brand Name English
ORLEX HC COMPONENT HYDROCORTISONE
Common Name English
ACETASOL HC COMPONENT HYDROCORTISONE
Common Name English
HYDROCORTISONE COMPONENT OF ACETASOL HC
Common Name English
VOSOL HC COMPONENT HYDROCORTISONE
Common Name English
CETACORT
Brand Name English
CORT-DOME
Brand Name English
DERMACORT
Brand Name English
HYDROCORTISONUM [WHO-IP LATIN]
Common Name English
BALNEOL-HC
Brand Name English
HYDROCORTISONE HYDROGEN SUCCINATE IMPURITY A [EP IMPURITY]
Common Name English
OTICAIR COMPONENT HYDROCORTISONE
Common Name English
HYDROCORTISONE COMPONENT OF ORLEX HC
Common Name English
CIPRO HC COMPONENT HYDROCORTISONE
Common Name English
HYDROCORTISONE COMPONENT OF OTOCORT
Common Name English
hydrocortisone [INN]
Common Name English
HYDROCORTISONE COMPONENT OF VOSOL HC
Common Name English
NUTRACORT
Brand Name English
ACTICORT
Brand Name English
PENECORT
Brand Name English
HYDROCORTISONE [HSDB]
Common Name English
HYDROCORTISONE COMPONENT OF PEDIOTIC
Common Name English
PREDNISOLONE IMPURITY A [EP IMPURITY]
Common Name English
HYDROCORTISONE [EP MONOGRAPH]
Common Name English
ELDECORT
Brand Name English
HYTONE
Brand Name English
ALA-SCALP
Brand Name English
HYDROCORTISONE COMPONENT OF ALPHADERM
Common Name English
ALPHADERM COMPONENT HYDROCORTISONE
Common Name English
11.BETA.,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE
Systematic Name English
HYDROCORTISONE SODIUM SUCCINATE IMPURITY A [EP IMPURITY]
Common Name English
ALKINDI SPRINKLE
Brand Name English
ALA-CORT
Brand Name English
HYDROCORTISONE COMPONENT OF CIPRO HC
Common Name English
HYDROCORTISONE ACETATE IMPURITY A [EP IMPURITY]
Common Name English
OTOBIOTIC COMPONENT HYDROCORTISONE
Common Name English
Classification Tree Code System Code
LIVERTOX 485
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S01CB03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QA01AC03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 53346-3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S02CA03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS01CA03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS03CA04
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.1662A
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 18.1
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QR01AD60
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S01CA03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
FDA ORPHAN DRUG 234906
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 2144-4
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
FDA ORPHAN DRUG 441614
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
EMA ASSESSMENT REPORTS PLENADREN (AUTHORIZED: ADRENAL INSUFFICIENCY)
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S03CA04
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 44310-1
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 35202-1
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 78988-3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 14675-3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QD07AA02
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS02BA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 32310-5
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
EU-Orphan Drug EU/3/06/372
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS02CA03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC D07AA02
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QA07EA02
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.1484D
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QH02AB09
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 26828-4
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 51844-9
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QC05AA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC A01AC03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
FDA ORPHAN DRUG 487515
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS01BB01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.1132
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 15043-3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC R01AD60
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QD07XA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 53337-2
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
NDF-RT N0000175576
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QD07BA04
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.1484I
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
EPA PESTICIDE CODE 6312
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
NDF-RT N0000175450
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS01BA02
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S01BB01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 83089-3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.1484H
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
FDA ORPHAN DRUG 467014
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 53336-4
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 83090-1
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC D07BA04
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 28550-2
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC D07CA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 83088-5
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 50848-1
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC H02AB09
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 33257-7
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 2142-8
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 11155-9
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S02BA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QD07CA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC A07EA02
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 76352-4
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC C05AA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 17.3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 20622-7
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 13.3
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 50336-7
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 53345-5
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC S01BA02
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-ATC D07XA01
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
WHO-VATC QS01CB03
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
FDA ORPHAN DRUG 716719
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 83091-9
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.1204
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 14158-0
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 45184-9
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
NCI_THESAURUS C2323
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 76347-4
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
CFR 21 CFR 524.155
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
LOINC 2143-6
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
Code System Code Type Description
RXCUI
5492
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY RxNorm
INN
38
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
DAILYMED
WI4X0X7BPJ
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
LACTMED
Hydrocortisone
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
LACTMED
Hydrocortisone, Topical
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
DRUG BANK
DB00741
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
PUBCHEM
5754
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
FDA UNII
WI4X0X7BPJ
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
RS_ITEM_NUM
1316004
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
WIKIPEDIA
CORTISOL
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
SMS_ID
100000092635
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
IUPHAR
2868
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
CAS
50-23-7
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
EVMPD
SUB08065MIG
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
MERCK INDEX
m6094
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY Merck Index
CHEBI
17650
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
DRUG CENTRAL
1388
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
ChEMBL
CHEMBL389621
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
NCI_THESAURUS
C555
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
HYDROCORTISONE
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder; odourless. Solubility: Very slightly soluble in water and ether R; sparingly soluble in ethanol (~750 g/l) TS and acetone R. Category: Adrenocortical steroid. Storage: Hydrocortisone should be kept in a well-closed container, protected from light. Additional information: Hydrocortisone melts at about 214?C with decomposition. Definition: Hydrocortisone contains not less than 97.0% and not more than 102.0% of C21H30O5, calculated with reference to the dried substance.
HSDB
3339
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
EPA CompTox
DTXSID7020714
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-020-1
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
NSC
10483
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
MESH
D006854
Created by admin on Fri Dec 15 15:16:08 UTC 2023 , Edited by admin on Fri Dec 15 15:16:08 UTC 2023
PRIMARY
Related Record Type Details
MULTIDRUG RESISTANCE PROTEIN 1
TRANSPORTER -> SUBSTRATE
CYTOCHROME P450 3A5
METABOLIC ENZYME -> SUBSTRATE
MINERALOCORTICOID RECEPTOR
TARGET -> AGONIST
2.4 FOLD INDUCTION OF GR MMTV-liciferase reporter gene
AGONIST
FOLD INDUCTION
GLUCOCORTICOID RECEPTOR
TARGET -> AGONIST
2.4 FOLD INDUCTION OF GR MMTV-luciferase reporter gene
AGONIST
FOLD INDUCTION
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
Structure of TETRAHYDROCORTISONE
METABOLITE -> PARENT
Structure of 17,20,21-TRIHYDROXYPREGN-4-ENE-3,11-DIONE
METABOLITE -> PARENT
Structure of CORTISONE
PARENT -> METABOLITE ACTIVE
Metabolite to parent drug ratio in non-uraemic human plasma.
METABOLITE TO PARENT DRUG RATIO
PLASMA
Related Record Type Details
Structure of HYDROCORTISONE-17-ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 7.ALPHA.-HYDROXYHYDROCORTISONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYDROCORTISONE ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 6-DEHYDROCORTISOL
IMPURITY -> PARENT
correction factor: for the calculation of content, multiply the peak area of impurity E by 2.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PREDNISOLONE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYDROCORTISONE 21-ALDEHYDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (11.BETA.)-11,14,17,21-TETRAHYDROXYPREGN-4-ENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 6.BETA.-HYDROXYCORTISOL
IMPURITY -> PARENT
correction factor: for the calculation of content, multiply the peak area of impurity D by 1.8
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CORTISONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PREDNISOLONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 11.BETA.,17,21-TRIHYDROXY-21-(11.BETA.,17,21-TRIHYDROXY-3,20-DIOXOPREGN-4-EN-21-YL)PREGN-4-ENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 21-DEOXYCORTISOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYDROCORTISONE HEMISUCCINATE ANHYDROUS
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 11-DEOXYCORTISOL 21-ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 11-EPIHYDROCORTISONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CORTODOXONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of HYDROCORTISONE
ACTIVE MOIETY
NIH
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National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966