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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H24N2O9.2H2O
Molecular Weight 496.4645
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXYTETRACYCLINE

SMILES

O.O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)C4=C(O)C=CC=C4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

InChIKey=SRRPEXWCHWWJOC-JEKSYDDFSA-N
InChI=1S/C22H24N2O9.2H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);2*1H2/t12-,13-,14+,17+,21-,22+;;/m1../s1

HIDE SMILES / InChI
Molecular Formula C22H24N2O9
Molecular Weight 460.434
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:06:01 UTC 2023
Edited
by admin
on Fri Dec 15 15:06:01 UTC 2023
Record UNII
X20I9EN955
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OXYTETRACYCLINE
GREEN BOOK   JAN   ORANGE BOOK   USP   USP-RS   VANDF  
USP  
Official Name English
OXYTETRACYCLINE [USP-RS]
Common Name English
OXYTETRACYCLINE DIHYDRATE [GREEN BOOK]
Common Name English
OXYTETRACYCLINUM DIHYDRAS [WHO-IP LATIN]
Common Name English
TERRAFUNGINE
Common Name English
NITOX
Common Name English
2-NAPHTHACENECARBOXAMIDE, 4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,6,10,12,12A-HEXAHYDROXY-6-METHYL-1,11-DIOXO-, (4S-(4.ALPHA.,4A.ALPHA.,5.ALPHA.,5A.ALPHA.,6.BETA.,12A.ALPHA.))-, DIHYDRATE
Common Name English
NSC-757262
Code English
OXYTETRACYCLINE [USP MONOGRAPH]
Common Name English
OXYTETRACYCLINE [GREEN BOOK]
Common Name English
OXYTETRACYCLINE [VANDF]
Common Name English
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide dihydrate
Common Name English
OXYTETRACYCLINE DIHYDRATE [EP MONOGRAPH]
Common Name English
TERRAMYCINE
Common Name English
OXITETRACYCLINE
Common Name English
Oxytetracycline dihydrate [WHO-DD]
Common Name English
TERRAMYCIN
Brand Name English
OXYTETRACYCLINE DIHYDRATE
EP   GREEN BOOK   WHO-DD  
Common Name English
OXYTETRACYCLINE [ORANGE BOOK]
Common Name English
OXYTETRACYCLINE [JAN]
Common Name English
5-HYDROXYTETRACYCLINE DIHYDRATE
Common Name English
OXYTETRACYCLINE DEHYDRATE [WHO-IP]
Common Name English
Classification Tree Code System Code
WHO-ATC D06AA03
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QG51AG06
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QG01AA07
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
NCI_THESAURUS C1595
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 556.500
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 520.1660
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QS01AA04
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-ATC S01AA04
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-ATC J01AA56
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 520.1660D
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 520.1660A
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 524.1662A
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 522.1660A
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QG51AA01
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 558.455
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QD06AA03
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 524.1662B
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 333.120
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 558.450
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QD06AA53
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
NDF-RT N0000175505
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-ATC G01AA07
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
LIVERTOX NBK547920
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QJ01AA06
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 522.1660B
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-VATC QJ51AA06
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-ATC J01AA20
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 524.1662
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 522.1660
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
WHO-ATC J01AA06
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
CFR 21 CFR 522.1664
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
Code System Code Type Description
RXCUI
266974
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
DRUG CENTRAL
2041
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
EVMPD
SUB03601MIG
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
RS_ITEM_NUM
1491004
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
DRUG BANK
DB00595
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
FDA UNII
X20I9EN955
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
CHEBI
133011
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
OXYTETRACYCLINE
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY Description: A pale yellow, crystalline powder; odourless. Solubility: Very slightly soluble in water; sparingly soluble in ethanol (~750 g/l) TS; freely soluble in dilute acids and alkalis. Category: Antibacterial drug. Storage: Oxytetracycline dihydrate should be kept in a tightly closed container, protected from light.Labelling: The designation sterile Oxytetracycline dihydrate indicates that the substance complies with the additional requirements for sterile Oxytetracycline dihydrate and may be used for parenteral administration or for other sterile applications.Additional information: Oxytetracycline dihydrate darkens on exposure to strong sunlight. It deteriorates in solutions having a pH below 2 and is rapidly destroyed by alkali hydroxide solutions.Definition: Oxytetracycline dihydrate contains not less than 920 International Units of Oxytetracycline per mg, calculated withreference to the anhydrous substance.
CAS
6153-64-6
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
EPA CompTox
DTXSID4023412
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
ALANWOOD
oxytetracycline
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
SMS_ID
100000085515
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
MESH
D010118
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
NSC
757262
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
LACTMED
Oxytetracycline
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
WIKIPEDIA
OXYTETRACYCLINE
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
NCI_THESAURUS
C61872
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
DAILYMED
X20I9EN955
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
RXCUI
7821
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
ALTERNATIVE
ChEMBL
CHEMBL1517
Created by admin on Fri Dec 15 15:06:01 UTC 2023 , Edited by admin on Fri Dec 15 15:06:01 UTC 2023
PRIMARY
Related Record Type Details
Structure of OXYTETRACYCLINE ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
Structure of OXYTETRACYCLINE ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of OXYTETRACYCLINE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of OXYTETRACYCLINE ANHYDROUS
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of TETRACYCLINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 4-EPIOXYTETRACYCLINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-ACETYL-2-DECARBAMOYLOXYTETRACYCLINE
IMPURITY -> PARENT
(eluting on the tail of the principal peak): not more than 4 times the area of the peak due to impurity A in the chromatogram obtained with reference solution (e)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of OXYTETRACYCLINE ANHYDROUS
ACTIVE MOIETY
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