ARTEMOTIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H28O5
Molecular Weight	312.4012
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ARTEMOTIL

Structure Search

SMILES

[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@H](OCC)[C@@H]2C)O4

InChI

InChIKey=NLYNIRQVMRLPIQ-XQLAAWPRSA-N

InChI=1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H28O5
Molecular Weight	312.4012
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:10 UTC 2023` Edited by `admin` on `Fri Dec 15 15:40:10 UTC 2023`
Record UNII	XGL7GFB9YI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ARTEMOTIL

Official Name

English

ARTEMOTIL [WHO-IP]

Common Name

English

Artemotil [WHO-DD]

Common Name

English

ARTEMOTIL [MART.]

Common Name

English

artemotil [INN]

Common Name

English

(3R,5AS,6R,8AS,9R,10S,12R,12AR)-10-ETHOXYDECAHYDRO-3,6,9-TRIMETHYL-3,12-EPOXY-12H-PYRANO(4,3-J)-1,2-BENZODIOXEPIN

Common Name

English

NSC-665971

Code

English

ARTEETHER [WHO-IP]

Common Name

English

.BETA.-ARTEETHER [WHO-IP]

Common Name

English

ARTEETHER [MI]

Common Name

English

ARTEMOTILUM [WHO-IP LATIN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

P01BE04

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

Code System Code Type Description

PUBCHEM

3000469

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

MESH

C055141

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

EVMPD

SUB00596MIG

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

CAS

75887-54-6

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

ARTEMOTIL

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

Description: A white or almost white, crystalline powder. Solubility: Practically insoluble in water; sparingly soluble in dichloromethane R, ethanol (~750 g/l) TS and methanol R; soluble inarachis oil R and sesame oil R. Category: Antimalarial drug. Storage: Artemotil should be kept in a well-closed container, protected from light. Labelling: The designation Artemotil for parenteral use indicates that the substance complies with the additional requirements and may be used for parenteral administration. Additional information: The parenteral form is normally intended for intramuscular administration. Requirement: Artemotil contains not less than 97.0% and not more than the equivalent of 102.0% of C17H28O5 calculated with reference to the dried substance.

DRUG BANK

DB13851

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

NSC

665971

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

DRUG CENTRAL

246

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

SMS_ID

100000085322

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

MERCK INDEX

m2073

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

Merck Index

INN

6457

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

WIKIPEDIA

ARTEMOTIL

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

NCI_THESAURUS

C73002

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

ChEMBL

CHEMBL301267

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

FDA UNII

XGL7GFB9YI

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

EPA CompTox

DTXSID6057821

Created by admin on Fri Dec 15 15:40:10 UTC 2023 , Edited by admin on Fri Dec 15 15:40:10 UTC 2023

PRIMARY

Related Record Type Details


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR

Amount:


					0UY97CSG1T

CYTOCHROME P450 2B6

METABOLIC ENZYME -> SUBSTRATE

Amount:


					805SU96HKF

CYTOCHROME P450 3A5

METABOLIC ENZYME -> SUBSTRATE

Amount:

Related Record Type Details


					6A9O50735X

ARTENIMOL

METABOLITE ACTIVE -> PARENT

Amount:

Related Record Type Details


					XGL7GFB9YI

ARTEMOTIL

ACTIVE MOIETY

Comments:

http://apps.who.int/phint/pdf/b/Jb.6.1.32.pdf

Amount: