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Details

Stereochemistry ACHIRAL
Molecular Formula C12H18O
Molecular Weight 178.2707
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROPOFOL

SMILES

CC(C)C1=CC=CC(C(C)C)=C1O

InChI

InChIKey=OLBCVFGFOZPWHH-UHFFFAOYSA-N
InChI=1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

HIDE SMILES / InChI
Molecular Formula C12H18O
Molecular Weight 178.2707
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:59:02 UTC 2023
Edited
by admin
on Sat Dec 16 17:59:02 UTC 2023
Record UNII
YI7VU623SF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROPOFOL
EP   GREEN BOOK   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
PROPOFOL [USP-RS]
Common Name English
FRESOFOL
Brand Name English
PROPOFOL [EP MONOGRAPH]
Common Name English
PROPOFOL [HSDB]
Common Name English
DIPRIVAN
Brand Name English
ICI 35-868
Code English
PROPOFOL [MART.]
Common Name English
ICI35,868
Code English
PROPOFOL [USP IMPURITY]
Common Name English
KETAFOL COMPONENT PROPOFOL
Brand Name English
Propofol [WHO-DD]
Common Name English
ICI 35,868
Code English
PROPOFOL [ORANGE BOOK]
Common Name English
PROPOFOL [EP IMPURITY]
Common Name English
LIPURO
Brand Name English
PHENOL, 2,6-BIS(1-METHYLETHYL)
Common Name English
PROPOFOL [USP MONOGRAPH]
Common Name English
2,6-DIPROPAN-2-YLPHENOL
Systematic Name English
ICI-35868
Code English
PROPOFOL [MI]
Common Name English
PROPOFOL [JAN]
Common Name English
2,6-Diisopropylphenol
Systematic Name English
propofol [INN]
Common Name English
PROPOFOL [VANDF]
Common Name English
PROPOFOL [USAN]
Common Name English
PROPOFOL [GREEN BOOK]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29756
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
CFR 21 CFR 522.2005
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
WHO-ATC N01AX10
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
NDF-RT N0000175681
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
NDF-RT N0000175975
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
WHO-VATC QN01AX10
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
LIVERTOX NBK547909
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 1.1.2
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
Code System Code Type Description
MERCK INDEX
m9217
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY Merck Index
INN
5073
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
DRUG BANK
DB00818
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
NCI_THESAURUS
C29384
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
HSDB
7123
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
CHEBI
44915
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
EPA CompTox
DTXSID6023523
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
FDA UNII
YI7VU623SF
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
DAILYMED
YI7VU623SF
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
DRUG CENTRAL
2302
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
PUBCHEM
4943
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
SMS_ID
100000091539
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
MESH
D015742
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
LACTMED
Propofol
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
ChEMBL
CHEMBL526
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
IUPHAR
5464
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
USAN
U-89
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
CAS
2078-54-8
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
EVMPD
SUB10116MIG
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
RXCUI
8782
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
218-206-6
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
RS_ITEM_NUM
1572503
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
WIKIPEDIA
PROPOFOL
Created by admin on Sat Dec 16 17:59:03 UTC 2023 , Edited by admin on Sat Dec 16 17:59:03 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 2B6
METABOLIC ENZYME -> SUBSTRATE
Structure of PROPOFOL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9
METABOLIC ENZYME -> SUBSTRATE
Structure of PROPOFOL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Related Record Type Details
Structure of FOSPROPOFOL
PRODRUG -> METABOLITE ACTIVE
Related Record Type Details
Structure of DIPROPOFO
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 0.25
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2,6-DIISOPROPYLPHENYL ISOPROPYL ETHER
IMPURITY -> PARENT
test 1
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of ISOPROPYL 2-ISOPROPYLPHENYL ETHER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (GC)
EP
Structure of 2-ISOPROPYLPHENOL
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 4-HYDROXY-3,5-DIISOPROPYLBENZOIC ACID
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of M-ISOPROPYLPHENOL
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 2,6-DIISOPROPYLPHENYL ISOPROPYL ETHER
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 5.0
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIPROPOFO
IMPURITY -> PARENT
test 2
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of P-ISOPROPYLPHENOL
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of DIPROPOFO
IMPURITY -> PARENT
Limit of propofol related compound A?[note?This test is to be performed in conjunction with Related compounds Test 1. ]
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2,6-DIISOPROPYLPHENYL ISOPROPYL ETHER
IMPURITY -> PARENT
test 2
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2,6-DIISOPROPYLBENZOQUINONE
IMPURITY -> PARENT
Limit of propofol related compound B
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of DIPHENYL ETHER
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 2-(1-METHYLETHENYL)-6-(1-METHYLETHYL)PHENOL
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of ISOPROPYL 4-HYDROXY-3,5-BIS(ISOPROPYL)BENZOATE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 2-ISOPROPYL-6-PROPYLPHENOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (GC)
EP
Structure of 2,2-DIMETHYL-4-ISOPROPYL-1,3-BENZODIOXOLE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (GC)
EP
Structure of 2,5-DIISOPROPYLPHENOL
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 2,6-DIISOPROPYLBENZOQUINONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (GC)
EP
Structure of 2,4-DIISOPROPYLPHENOL
IMPURITY -> PARENT
UNSPECIFIED
EP
Related Record Type Details
Structure of PROPOFOL
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life Elimination
PHARMACOKINETIC
Elimination
PHARMACOKINETIC
Elimination
PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC After a 10-day infusion
PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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