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ISIS-463588
YJ4APB5MQC
Other
General
Record Details
Names
4
Identifiers
2
Subunits
1
Sugars
2
Linkages
1
Relationships
1
Active Moiety
1
Modifications
1
Characteristic Attributes
1
ISIS-463588
YJ4APB5MQC
Other
General
Approval Year
Unknown
86,413
Record Details
Substance Class
Nucleic Acid
Nucleic Acid Type
OLIGONUCLEOTIDE
Nucleic Acid Subtype
ANTI-SENSE
Sequence Type
COMPLETE
Record UNII
YJ4APB5MQC
Record Status
Validated (UNII)
Record Version
6
5
4
3
2
1
Names
4
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Name
Type
Language
Name
Type
Language
ISIS-463588
Code
English
DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-M5C-T-M5C-A-G-M5C-A-G-G-A-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))
Systematic Name
English
IONIS-FGFR4RX
Code
English
ISIS-FGFR4RX
Code
English
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2
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Code System
Code
Type
Description
Code System
Code
Type
Description
FDA UNII
YJ4APB5MQC
PRIMARY
CAS
1416376-17-4
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Sugars
2
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Sugar
Site Range
Site Count
Sugar
Site Range
Site Count
Deoxyribose (DNA)
1_6-1_15
10 / 20
2'-O-Methoxyethyl ribose
1_1-1_5;1_16-1_20
10 / 20
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Linkages
1
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Linkage
Site Range
Site Count
Linkage
Site Range
Site Count
Phosporothioate
1_2-1_20
19 / 19
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1
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Related Record
Type
Details
Related Record
Type
Details
3F84ING33L
FIBROBLAST GROWTH FACTOR RECEPTOR 4
TARGET->INHIBITOR OF EXPRESSION
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1
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Related Record
Type
Details
Related Record
Type
Details
YJ4APB5MQC
ISIS-463588
ACTIVE MOIETY
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Modifications
1
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
NUCLEOSIDE_SUBSTITUTION
[1_2] [1_4] [1_6] [1_8] [1_11] [1_16] [1_17] [1_18] [1_19] [1_20]
SITE_SPECIFIC
2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE
AOQ54IZZ6J
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Characteristic Attributes
1
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
NUMBER 7203 Da (average)
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