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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H31NO2
Molecular Weight 341.487
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DESFESOTERODINE

SMILES

CC(C)N(CC[C@H](C1=CC=CC=C1)C2=CC(CO)=CC=C2O)C(C)C

InChI

InChIKey=DUXZAXCGJSBGDW-HXUWFJFHSA-N
InChI=1S/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1

HIDE SMILES / InChI
Molecular Formula C22H31NO2
Molecular Weight 341.487
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:41:46 UTC 2023
Edited
by admin
on Fri Dec 15 16:41:46 UTC 2023
Record UNII
YU871O78GR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DESFESOTERODINE
INN   WHO-DD  
INN  
Official Name English
(+)-N,N-DIISOPROPYL-3-(2-HYDROXY-5-HYDROXYMETHYLPHENYL)-3-PHENYLPROPYLAMINE
Systematic Name English
SPM-7605
Code English
(R)-(+)-2-(3-DIISOPROPYLAMINO-1-PHENYLPROPYL)-4-HYDROXYMETHYLPHENOL
Systematic Name English
desfesoterodine [INN]
Common Name English
Desfesoterodine [WHO-DD]
Common Name English
5-HYDROXYMETHYLTOLTERODINE
Common Name English
PNU-200577
Code English
BENZENEMETHANOL, 3-((1R)-3-(BIS(1-METHYLETHYL)AMINO)-1-PHENYLPROPYL)-4-HYDROXY-
Systematic Name English
Classification Tree Code System Code
WHO-ATC G04BD13
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
Code System Code Type Description
EVMPD
SUB179842
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
NCI_THESAURUS
C169886
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
SMS_ID
100000165970
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
WIKIPEDIA
Desfesoterodine
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
FDA UNII
YU871O78GR
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
CAS
207679-81-0
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
DRUG BANK
DB15578
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
EPA CompTox
DTXSID40431319
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
PUBCHEM
9819382
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
INN
10020
Created by admin on Fri Dec 15 16:41:46 UTC 2023 , Edited by admin on Fri Dec 15 16:41:46 UTC 2023
PRIMARY
Related Record Type Details
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
CYTOCHROME P450 2D6
METABOLIC ENZYME -> SUBSTRATE
MAJOR
Structure of DESFESOTERODINE SUCCINATE
SALT/SOLVATE -> PARENT
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
MAJOR
MUSCARINIC ACETYLCHOLINE RECEPTOR M3
TARGET -> INHIBITOR
Related Record Type Details
Structure of DE(ISOPROPYL)DESFESOTERODINE
METABOLITE INACTIVE -> PARENT
FECAL
Structure of PNU-200579
METABOLITE INACTIVE -> PARENT
PLASMA
Structure of DE(ISOPROPYL)DESFESOTERODINE
METABOLITE INACTIVE -> PARENT
PLASMA
Structure of PNU-200579
METABOLITE INACTIVE -> PARENT
URINE
Structure of DE(ISOPROPYL)TOLTERODINE-5-CARBOXYLIC ACID
METABOLITE INACTIVE -> PARENT
FECAL
Structure of PNU-200579
METABOLITE INACTIVE -> PARENT
FECAL
Structure of DE(ISOPROPYL)DESFESOTERODINE
METABOLITE INACTIVE -> PARENT
URINE
Structure of DE(ISOPROPYL)TOLTERODINE-5-CARBOXYLIC ACID
METABOLITE INACTIVE -> PARENT
PLASMA
Structure of DE(ISOPROPYL)TOLTERODINE-5-CARBOXYLIC ACID
METABOLITE INACTIVE -> PARENT
URINE
Structure of FESOTERODINE
PRODRUG -> METABOLITE ACTIVE
MAJOR
URINE
Structure of FESOTERODINE
PRODRUG -> METABOLITE ACTIVE
Extensive hydrolysis by nonspecific esterases
MAJOR
PLASMA
Structure of FESOTERODINE
PRODRUG -> METABOLITE ACTIVE
FECAL
Structure of TOLTERODINE
PARENT -> METABOLITE ACTIVE
MAJOR
Related Record Type Details
Structure of DESFESOTERODINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC INTRAVENOUS ADMINISTRATION

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