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Details

Stereochemistry ACHIRAL
Molecular Formula C12H13ClN4
Molecular Weight 248.711
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PYRIMETHAMINE

SMILES

CCC1=C(C(N)=NC(N)=N1)C2=CC=C(Cl)C=C2

InChI

InChIKey=WKSAUQYGYAYLPV-UHFFFAOYSA-N
InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

HIDE SMILES / InChI
Molecular Formula C12H13ClN4
Molecular Weight 248.711
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:21:23 UTC 2023
Edited
by admin
on Fri Dec 15 15:21:23 UTC 2023
Record UNII
Z3614QOX8W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PYRIMETHAMINE
EP   GREEN BOOK   INN   JAN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN  
Official Name English
PYRIMETHAMINE [MART.]
Common Name English
PYRIMETHAMINE [WHO-IP]
Common Name English
FANSIDAR COMPONENT PYRIMETHAMINE
Common Name English
RP-4753
Code English
2,4-DIAMINO-5-(P-CHLOROPHENYL)-6-ETHYLPYRIMIDINE
Common Name English
PYRIMETHAMINE [VANDF]
Common Name English
CHLORIDINE
Common Name English
DARAPRIM
Brand Name English
Pyrimethamine [WHO-DD]
Common Name English
PYRIMETHAMINE COMPONENT OF FANSIDAR
Common Name English
WR-2978
Code English
PYRIMETHAMINE [JAN]
Common Name English
PYRIMETHAMINE [USP MONOGRAPH]
Common Name English
PYRIMETHAMINE [IARC]
Common Name English
pyrimethamine [INN]
Common Name English
PYRIMETHAMINE [MI]
Common Name English
PYRIMETHAMINE [GREEN BOOK]
Common Name English
GNF-PF-5586
Code English
TCMDC-125860
Code English
PYRIMETHAMINE [EP MONOGRAPH]
Common Name English
PYRIMETHAMINE [USP-RS]
Common Name English
PYRIMETHAMINUM [WHO-IP LATIN]
Common Name English
2,4-PYRIMIDINEDIAMINE, 5-(4-CHLOROPHENYL)-6-ETHYL-
Systematic Name English
NSC-3061
Code English
PYRIMETHAMINE [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
LIVERTOX NBK548044
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
NDF-RT N0000000191
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
NDF-RT N0000000191
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
WHO-ATC P01BD51
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
NDF-RT N0000175934
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.5.3.1 (SUL/PYR)
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
FDA ORPHAN DRUG 232206
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
EPA PESTICIDE CODE 600071
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.5.4
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
IARC Pyrimethamine
NCI_THESAURUS C271
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
NCI_THESAURUS C2153
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
WHO-ATC P01BF04
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
CFR 21 CFR 520.2215
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
WHO-VATC QP51AX51
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
WHO-ATC P01BD01
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
Code System Code Type Description
MERCK INDEX
m9368
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY Merck Index
MESH
D011739
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
DAILYMED
Z3614QOX8W
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
RS_ITEM_NUM
1589007
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
PUBCHEM
4993
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
ChEMBL
CHEMBL36
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
PYRIMETHAMINE
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY Description: A white, crystalline powder; odourless. Solubility: Practically insoluble in water; slightly soluble in ethanol (~750 g/l) TS and acetone R. Category: Antimalarial. Storage: Pyrimethamine should be kept in a well-closed container, protected from light. Definition: Pyrimethamine contains not less than 99.0% and not more than 101.0% of C12H13ClN4, calculated with reference to the dried substance.
WIKIPEDIA
PYRIMETHAMINE
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
INN
2215
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
RXCUI
9010
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY RxNorm
CAS
58-14-0
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
CHEBI
8673
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
IUPHAR
4800
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
DRUG BANK
DB00205
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
FDA UNII
Z3614QOX8W
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
EVMPD
SUB10169MIG
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
NCI_THESAURUS
C788
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
NSC
3061
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
EPA CompTox
DTXSID9021217
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
SMS_ID
100000080868
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-364-2
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
LACTMED
Pyrimethamine
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
LACTMED
Sulfadoxine and Pyrimethamine
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
DRUG CENTRAL
2332
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
HSDB
8042
Created by admin on Fri Dec 15 15:21:23 UTC 2023 , Edited by admin on Fri Dec 15 15:21:23 UTC 2023
PRIMARY
Related Record Type Details
Structure of PYRIMETHAMINE PHOSPHATE
SALT/SOLVATE -> PARENT
Structure of PYRIMETHAMINE PAMOATE
SALT/SOLVATE -> PARENT
Structure of PYRIMETHAMINE TARTRATE
SALT/SOLVATE -> PARENT
Structure of PYRIMETHAMINE ISETHIONATE
SALT/SOLVATE -> PARENT
DIHYDROFOLATE REDUCTASE
TARGET -> INHIBITOR
Structure of PYRIMETHAMINE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Related Record Type Details
Structure of .ALPHA.-(4-CHLOROPHENYL)-2-ETHYL-1,3-DIOXOLANE-2-ACETONITRILE
IMPURITY -> PARENT
Structure of 4-CHLOROBENZYL CYANIDE
IMPURITY -> PARENT
Structure of 2-(4-CHLOROPHENYL)-3-OXOPENTANENITRILE
IMPURITY -> PARENT
Structure of 6-AMINO-5-(4-CHLOROPHENYL)-4-ETHYL-2(1H)-PYRIMIDINONE
IMPURITY -> PARENT
Structure of 2-AMINO-5-(4-CHLOROPHENYL)-6-ETHYL-1H-PYRIMIDIN-4-ONE
IMPURITY -> PARENT
Structure of 5-(4-CHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAMINE
IMPURITY -> PARENT
Related Record Type Details
Structure of PYRIMETHAMINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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