DAUNORUBICIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H29NO10
Molecular Weight	527.5199
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DAUNORUBICIN

Structure Search

SMILES

[H][C@@]1(C[C@@](O)(CC2=C(O)C3=C(C(=O)C4=C(C=CC=C4OC)C3=O)C(O)=C12)C(C)=O)O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5

InChI

InChIKey=STQGQHZAVUOBTE-VGBVRHCVSA-N

InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H29NO10
Molecular Weight	527.5199
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:14:46 UTC 2023` Edited by `admin` on `Fri Dec 15 16:14:46 UTC 2023`
Record UNII	ZS7284E0ZP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DAUNORUBICIN

Official Name

English

FI 6339

Code

English

RP 13057

Code

English

EPIRUBICIN IMPURITY D

Common Name

English

DAUNORUBICIN [MI]

Common Name

English

(8S,10S)-8-ACETYL-10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-6,8,11-TRIHYDROXY-1-METHOXY-7,8,9,10-TETRAHYDROTETRACENE-5,12-DIONE

Common Name

English

DAUNORUBICIN [HSDB]

Common Name

English

VYXEOS COMPONENT DAUNORUBICIN

Brand Name

English

RP-13057

Code

English

5,12-NAPHTHACENEDIONE, 8-ACETYL-10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL))OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-1-METHOXY-, (8S-CIS)-

Common Name

English

DAUNOMYCIN

Common Name

English

FI-6339

Code

English

Daunorubicin [WHO-DD]

Common Name

English

NSC-83142

Code

English

EPIRUBICIN HYDROCHLORIDE IMPURITY D [EP IMPURITY]

Common Name

English

EPIRUBICIN HYDROCHLORIDE IMPURITY, DAUNORUBICIN- [USP IMPURITY]

Common Name

English

VALRUBICIN IMPURITY, DAUNORUBICIN [USP IMPURITY]

Common Name

English

DAUNORUBICIN [MART.]

Common Name

English

DOXORUBICIN HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

(1S,3S)-3-ACETYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSIDE

Common Name

English

DAUNORUBICIN [ORANGE BOOK]

Common Name

English

DAUNORUBICIN [VANDF]

Common Name

English

daunorubicin [INN]

Common Name

English

DAUNOMYCIN [IARC]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175414

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

NCI_THESAURUS

C1594

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

FDA ORPHAN DRUG

265808

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

WHO-ATC

L01DB02

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

NDF-RT

N0000007530

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

8.2

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

WHO-ATC

L01XY01

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

NDF-RT

N0000000176

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

NDF-RT

N0000007530

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

LIVERTOX

NBK548259

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

NDF-RT

N0000007530

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

EU-Orphan Drug

EU/3/11/942

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

WHO-VATC

QL01DB02

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

Code System Code Type Description

HSDB

5095

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

INN

2257

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

EVMPD

SUB06917MIG

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

WIKIPEDIA

DAUNORUBICIN

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

ChEMBL

CHEMBL178

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

DRUG BANK

DB00694

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

PUBCHEM

30323

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

EPA CompTox

DTXSID7022883

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

NCI_THESAURUS

C62091

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

MESH

D003630

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

IUPHAR

7063

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

DAILYMED

ZS7284E0ZP

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

NSC

83142

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

MERCK INDEX

m4104

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

Merck Index

FDA UNII

ZS7284E0ZP

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

SMS_ID

100000086006

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

CAS

20830-81-3

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

CHEBI

41977

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

RXCUI

3109

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

RxNorm

DRUG CENTRAL

786

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

ECHA (EC/EINECS)

244-069-7

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

CHEBI

64677

Created by admin on Fri Dec 15 16:14:46 UTC 2023 , Edited by admin on Fri Dec 15 16:14:46 UTC 2023

PRIMARY

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ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2

TRANSPORTER -> INHIBITOR


					76UB6O122H

ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2

TRANSPORTER -> SUBSTRATE


					5L84T2Z6NP

DAUNORUBICIN CITRATE

SALT/SOLVATE -> PARENT


					UD984I04LZ

DAUNORUBICIN HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					4AF605U6JN

MRP-2

TRANSPORTER -> INHIBITOR


					Y49M64GZ4Q

MRP-1

TRANSPORTER -> SUBSTRATE

Amount:


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> SUBSTRATE

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					22966TX7J5

EPIRUBICIN HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					82F2G7BL4E

DOXORUBICIN HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					2C6NUM6878

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					ZS7284E0ZP

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC