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Development Status
US Approved Rx
618
US Previously Marketed
127
Possibly Marketed Outside US
44
US Approved OTC
21
Other
11
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Primary Target
Bacterial penicillin-binding protein
30
DNA
30
GABA-A receptor; anion channel
26
Histamine H1 receptor
20
Norepinephrine transporter
19
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Highest Phase
Approved
703
Phase III
4
Not Provided
3
Phase IV
3
Phase I
1
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Approval Year
1921
37
1995
23
1996
23
Unknown
23
2001
22
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Condition
Hypertension
49
Urinary tract infections
28
Rheumatoid arthritis
26
Pain
22
Osteoarthritis
19
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Treatment Modality
Primary
504
Curative
130
Palliative
124
Preventing
68
Secondary
30
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CNS Activity
CNS Penetrant
248
CNS Active
218
CNS Non-penetrant
93
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Originator
Merck
20
Pfizer
20
Bristol-Myers Squibb
15
Eli Lilly
13
Bayer
11
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Substance Class
Chemical
706
Protein
40
Structurally Diverse
36
Mixture
23
Polymer
10
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INN Stem
Chemical substance(-ine)
1
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GInAS Tag
KEW
4
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Code System
LIVERTOX
824
FDA UNII
815
EVMPD
813
RXCUI
809
NCI_THESAURUS
798
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Protein Type
MONOCLONAL ANTIBODY
16
CYTOKINE
2
ENZYME
1
FUSION PROTEIN
1
GROWTH FACTOR
1
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ATC Level 1
NERVOUS SYSTEM
149
ANTIINFECTIVES FOR SYSTEMIC USE
125
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
119
ALIMENTARY TRACT AND METABOLISM
115
CARDIOVASCULAR SYSTEM
90
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ATC Level 2
ANTINEOPLASTIC AGENTS
76
ANTIBACTERIALS FOR SYSTEMIC USE
75
OPHTHALMOLOGICALS
55
PSYCHOLEPTICS
45
PSYCHOANALEPTICS
37
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
41
DIRECT ACTING ANTIVIRALS
32
OTHER BETA-LACTAM ANTIBACTERIALS
29
IMMUNOSUPPRESSANTS
25
ANTIDEPRESSANTS
24
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ATC Level 4
Antibiotics
21
Protein kinase inhibitors
17
Other antineoplastic agents
16
Benzodiazepine derivatives
12
Selective immunosuppressants
12
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Substance Form
Principal Form
695
Salts, Hydrates, Esters, etc.
120
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Search results for
"LiverTox"
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(approximate match)
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Lacosamide
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563KS2PQY5
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Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
BENDAMUSTINE
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9266D9P3PQ
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CHEMICAL (ACHIRAL)
ETRAVIRINE
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0C50HW4FO1
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CHEMICAL (ACHIRAL)
SILODOSIN
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CUZ39LUY82
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CHEMICAL (ABSOLUTE)
RUFINAMIDE
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WFW942PR79
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Class (Stereo):
CHEMICAL (ACHIRAL)
DEGARELIX
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SX0XJI3A11
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Class (Stereo):
CHEMICAL (ABSOLUTE)
LAPATINIB
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0VUA21238F
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Class (Stereo):
CHEMICAL (ACHIRAL)
NILOTINIB
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F41401512X
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Class (Stereo):
CHEMICAL (ACHIRAL)
RALTEGRAVIR
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22VKV8053U
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Class (Stereo):
CHEMICAL (ACHIRAL)
TEMSIROLIMUS
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624KN6GM2T
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