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US Approved Rx
178
US Approved OTC
21
US Previously Marketed
20
Possibly Marketed Outside US
11
Other
9
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Primary Target
DNA
12
Bacterial penicillin-binding protein
10
Human immunodeficiency virus type 1 reverse transcriptase
7
GABA-A receptor; anion channel
6
Glucocorticoid receptor
6
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Highest Phase
Approved
213
Phase III
1
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Approval Year
1921
28
Unknown
14
1947
8
1953
8
1985
8
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Condition
Urinary tract infections
13
HIV-1 infection
9
Hypertension
9
Pain
9
Unknown
8
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Treatment Modality
Primary
135
Curative
67
Preventing
36
Palliative
31
Diagnostic
7
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CNS Activity
CNS Penetrant
93
CNS Active
51
CNS Non-penetrant
32
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Originator
Bayer
6
Merck
6
Burroughs Wellcome Fund
5
Pfizer
3
Rhône-Poulenc
3
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Substance Class
Chemical
208
Mixture
13
Concept
9
Structurally Diverse
7
Protein
2
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Code System
WHO-ESSENTIAL MEDICINES LIST
239
EVMPD
236
FDA UNII
230
RXCUI
229
DRUG BANK
228
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ATC Level 1
ANTIINFECTIVES FOR SYSTEMIC USE
57
ALIMENTARY TRACT AND METABOLISM
44
SENSORY ORGANS
39
DERMATOLOGICALS
30
NERVOUS SYSTEM
26
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ATC Level 2
OPHTHALMOLOGICALS
37
ANTIBACTERIALS FOR SYSTEMIC USE
29
ANTINEOPLASTIC AGENTS
14
ANTIPROTOZOALS
14
ALL OTHER THERAPEUTIC PRODUCTS
13
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ATC Level 3
ANTIINFECTIVES
14
ALL OTHER THERAPEUTIC PRODUCTS
13
DIRECT ACTING ANTIVIRALS
13
DRUGS FOR TREATMENT OF TUBERCULOSIS
11
STOMATOLOGICAL PREPARATIONS
11
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ATC Level 4
Antibiotics
15
Antidotes
10
Antiinfectives
7
Antivirals for treatment of HIV infections, combinations
7
Combinations of drugs for treatment of tuberculosis
7
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Substance Form
Principal Form
170
Salts, Hydrates, Esters, etc.
60
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NIFURTIMOX
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M84I3K7C2O
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Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
TRICLABENDAZOLE
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4784C8E03O
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CHEMICAL (ACHIRAL)
EMTRICITABINE
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G70B4ETF4S
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CHEMICAL (ABSOLUTE)
LOPINAVIR
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2494G1JF75
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CHEMICAL (ABSOLUTE)
EFAVIRENZ
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JE6H2O27P8
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Class (Stereo):
CHEMICAL (ABSOLUTE)
NEVIRAPINE
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99DK7FVK1H
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Class (Stereo):
CHEMICAL (ACHIRAL)
RITONAVIR
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O3J8G9O825
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CHEMICAL (ABSOLUTE)
LAMIVUDINE
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2T8Q726O95
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Class (Stereo):
CHEMICAL (ABSOLUTE)
METFORMIN
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9100L32L2N
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Class (Stereo):
CHEMICAL (ACHIRAL)
BISOPROLOL
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Y41JS2NL6U
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Class (Stereo):
CHEMICAL (RACEMIC)
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