U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H9NO2
Molecular Weight 151.1626
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETAMINOPHEN

SMILES

CC(=O)NC1=CC=C(O)C=C1

InChI

InChIKey=RZVAJINKPMORJF-UHFFFAOYSA-N
InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

HIDE SMILES / InChI
Molecular Formula C8H9NO2
Molecular Weight 151.1626
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:52:43 UTC 2023
Edited
by admin
on Sat Dec 16 16:52:43 UTC 2023
Record UNII
362O9ITL9D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ACETAMINOPHEN
HSDB   INCI   MI   ORANGE BOOK   USP   USP-RS   VANDF  
INCI  
Official Name English
ACETAMINOPHEN COMPONENT OF MEDIGESIC PLUS
Common Name English
NORCET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF ROXICET
Common Name English
ACETAMINOPHEN COMPONENT OF TALACEN
Common Name English
ACETAMINOPHEN [VANDF]
Common Name English
PHENAPHEN
Common Name English
NSC-109028
Code English
DURADYNE DHC COMPONENT ACETAMINOPHEN
Common Name English
TRIAPRIN COMPONENT ACETAMINOPHEN
Common Name English
PERCOCET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF DURADYNE DHC
Common Name English
ACETAMINOPHEN COMPONENT OF BANCAP
Common Name English
ACETAMINOPHEN [INCI]
Common Name English
PARACETAMOLUM [WHO-IP LATIN]
Common Name English
TRIAD COMPONENT ACETAMINOPHEN
Common Name English
ESGIC COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF SYNALGOS-DC-A
Common Name English
DHC PLUS COMPONENT ACETAMINOPHEN
Common Name English
PARACETAMOL [WHO-IP]
Common Name English
PERFALGAN
Brand Name English
ACETAMINOPHEN [ORANGE BOOK]
Common Name English
ACETAMINOPHEN COMPONENT OF LORTAB
Common Name English
LORCET-HD COMPONENT ACETAMINOPHEN
Common Name English
ACETAMIDE, N-(4-HYDROXYPHENYL)-
Systematic Name English
DAFALGAN
Brand Name English
COMBOGESIC COMPONENT ACETAMINOPHEN
Brand Name English
ACETAMINOPHEN COMPONENT OF FIORICET
Common Name English
SEDAPAP COMPONENT ACETAMINOPHEN
Common Name English
OFIRMEV
Brand Name English
MEDIGESIC PLUS COMPONENT ACETAMINOPHEN
Common Name English
DRIXORAL PLUS COMPONENT ACETAMINOPHEN
Common Name English
P-HYDROXY-ACETANILID
Common Name English
PARACETAMOL [MART.]
Common Name English
4'-HYDROXYACETANILIDE
Systematic Name English
VICODIN COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN [USP IMPURITY]
Common Name English
ACETAMINOPHEN COMPONENT OF BUCET
Common Name English
EFFERALGAN
Brand Name English
ZYDONE COMPONENT ACETAMINOPHEN
Common Name English
NORCO COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN [MI]
Common Name English
FEMCET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF OXYCET
Common Name English
PARACETAMOL [EP MONOGRAPH]
Common Name English
ALLAY COMPONENT ACETAMINOPHEN
Common Name English
BIOCETAMOL
Common Name English
ACETAMINOPHEN COMPONENT OF DHC PLUS
Common Name English
ACETAMINOPHEN COMPONENT OF ROXILOX
Common Name English
ACETAMINOPHEN COMPONENT OF COMBOGESIC
Brand Name English
PARACETAMOL [IARC]
Common Name English
APAP
Common Name English
ACETAMINOPHEN COMPONENT OF NORCO
Common Name English
LORTAB COMPONENT ACETAMINOPHEN
Common Name English
NEOPAP
Brand Name English
ACETAMINOPHEN COMPONENT OF DOLENE AP-65
Common Name English
COMBOGESIC IV COMPONENT ACETAMINOPHEN
Brand Name English
ANEXSIA COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF VICODIN
Common Name English
ACETAMINOPHEN COMPONENT OF WYGESIC
Common Name English
FIORICET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN [JAN]
Common Name English
ACETAMINOPHEN [USP-RS]
Common Name English
ACETAMINOPHEN COMPONENT OF EXCEDRIN
Common Name English
CODRIX COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN [USP MONOGRAPH]
Common Name English
PHRENILIN COMPONENT ACETAMINOPHEN
Common Name English
HY-PHEN COMPONENT ACETAMINOPHEN
Common Name English
TYCOLET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF TYCOLET
Common Name English
PARACETAMOL
EP   INN   MART.   WHO-DD   WHO-IP  
INN  
Official Name English
ACETAMINOPHEN COMPONENT OF CO-GESIC
Common Name English
BUCET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF NORCET
Common Name English
TENCON COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF LORCET-HD
Common Name English
ACETAMINOPHEN [HSDB]
Common Name English
ROXICET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF TENCON
Common Name English
TREZIX COMPONENT ACETAMINOPHEN
Brand Name English
EXCEDRIN COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF CODRIX
Common Name English
paracetamol [INN]
Common Name English
ACETAMINOPHEN COMPONENT OF ALLAY
Common Name English
TYLENOL
Brand Name English
ACETAMINOPHEN COMPONENT OF HY-PHEN
Common Name English
DARVOCET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF TYLOX
Common Name English
XARTEMIS COMPONENT ACETAMINOPHEN
Brand Name English
ACETAMINOPHEN COMPONENT OF TRIAD
Common Name English
NSC-3991
Code English
ACETAMINOPHEN COMPONENT OF SEDAPAP
Common Name English
ULTRACET COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF XARTEMIS
Brand Name English
ANOQUAN COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF ULTRACET
Common Name English
N-ACETYL-P-AMINOPHENOL
Common Name English
ACETAMINOPHEN COMPONENT OF ANOQUAN
Common Name English
ROXILOX COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF BUTAPAP
Common Name English
ACETAMINOPHEN COMPONENT OF BANCAP HC
Common Name English
ACETAMINOPHEN COMPONENT OF PERCOCET
Common Name English
ACETAMINOPHEN COMPONENT OF DARVOCET
Common Name English
ACETAMINOPHEN COMPONENT OF ANEXSIA
Common Name English
BUTAPAP COMPONENT ACETAMINOPHEN
Common Name English
BANCAP HC COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF ZYDONE
Common Name English
Paracetamol [WHO-DD]
Common Name English
ACETAMINOPHEN COMPONENT OF TRIAPRIN
Common Name English
DOLIPRANE
Common Name English
BANCAP COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF DRIXORAL PLUS
Common Name English
TYLOX COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF ESGIC
Common Name English
CO-GESIC COMPONENT ACETAMINOPHEN
Common Name English
VERMIDON
Common Name English
OXYCET COMPONENT ACETAMINOPHEN
Common Name English
ACEPHEN
Brand Name English
ACETAMINOPHEN COMPONENT OF PHRENILIN
Common Name English
WYGESIC COMPONENT ACETAMINOPHEN
Common Name English
INJECTAPAP
Brand Name English
SYNALGOS-DC-A COMPONENT ACETAMINOPHEN
Common Name English
TALACEN COMPONENT ACETAMINOPHEN
Common Name English
DOLENE AP-65 COMPONENT ACETAMINOPHEN
Common Name English
ACETAMINOPHEN COMPONENT OF FEMCET
Common Name English
PANADOL
Brand Name English
Classification Tree Code System Code
WHO-ATC N02AJ17
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
CFR 21 CFR 341.40
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-VATC QN02BE71
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
NCI_THESAURUS C2356
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 7.1
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-VATC QN02BE01
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ATC N02AJ06
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
CFR 21 CFR 862.3030
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ATC N02BE71
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
CFR 21 CFR 310.201
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
EPA PESTICIDE CODE 606318
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-VATC QN02BE51
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
LOINC 75071-1
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ATC N02BE51
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ATC N02BE01
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ATC N02AJ13
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 2.1
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
LIVERTOX NBK548162
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
WHO-ATC N02AJ01
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
Code System Code Type Description
RS_ITEM_NUM
1003009
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
EVMPD
SUB09611MIG
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
EPA CompTox
DTXSID2020006
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
DAILYMED
362O9ITL9D
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
PUBCHEM
1983
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
DRUG BANK
DB00316
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
WIKIPEDIA
PARACETAMOL
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
CAS
8055-08-1
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
SUPERSEDED
LACTMED
Acetaminophen
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
MERCK INDEX
m1317
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY Merck Index
WHO INTERNATIONAL PHARMACOPEIA
ACETAMINOPHEN
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY Description: A white, crystalline powder; odourless. Solubility: Sparingly soluble in water; freely soluble in ethanol (~750 g/l) TS and acetone R; practically insoluble in ether R. Category: Analgesic; antipyretic. Storage: Paracetamol should be kept in a tightly closed container, protected from light. Definition: Paracetamol contains not less than 98.5% and not more than 101.0% of C8H9NO2, calculated with reference to thedried substance.
INN
626
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
NSC
109028
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
SMS_ID
100000090270
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
ECHA (EC/EINECS)
203-157-5
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
FDA UNII
362O9ITL9D
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
ChEMBL
CHEMBL112
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
DRUG CENTRAL
52
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
RXCUI
161
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY RxNorm
HSDB
3001
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
CHEBI
46195
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
NSC
3991
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
MESH
D000082
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
CAS
103-90-2
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
IUPHAR
5239
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
NCI_THESAURUS
C198
Created by admin on Sat Dec 16 16:52:51 UTC 2023 , Edited by admin on Sat Dec 16 16:52:51 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 1A2
METABOLIC ENZYME -> SUBSTRATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of POTASSIUM 4-ACETAMIDOPHENOLATE
SALT/SOLVATE -> PARENT
ARYLAMINE N-ACETYLTRANSFERASE 2
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 2E1
METABOLIC ENZYME -> SUBSTRATE
Enzyme responsible for the bulk of NAPQI formation
MAJOR
Structure of 4-HYDROXYACETANILIDE SODIUM
SALT/SOLVATE -> PARENT
CYTOCHROME P450 3A5
METABOLIC ENZYME -> SUBSTRATE
Structure of ACETAMINOPHEN
BASIS OF STRENGTH->SUBSTANCE
ASSAY (UV)
USP
Related Record Type Details
Structure of VORINOSTAT
PARENT -> METABOLITE
Structure of ACETAMINOPHEN MERCAPTURATE
METABOLITE INACTIVE -> PARENT
URINE
Structure of ACETAMINOPHEN SULFATE
METABOLITE INACTIVE -> PARENT
Major metabolite in infants and young children glucuronide is major metabolite in adults.
MAJOR
URINE
Structure of 3-CYSTEINYLACETAMINOPHEN
METABOLITE INACTIVE -> PARENT
URINE
Structure of 3-GLUTATHIONYLACETAMINOPHEN
METABOLITE -> PARENT
Structure of ACETAMINOPHEN GLUCURONIDE
METABOLITE INACTIVE -> PARENT
MAJOR
URINE
Structure of PHENACETIN
PARENT -> METABOLITE ACTIVE
Percent of dose excreted in urine as metabolite.
AMOUNT ADMINISTERED
URINE
Structure of AM-404
METABOLITE ACTIVE -> PARENT
Structure of 3-HYDROXYACETAMINOPHEN
METABOLITE -> PARENT
MINOR
PLASMA
Structure of 3-METHYL-THIOACETAMINOPHEN GLUCURONIDE
METABOLITE -> PARENT
URINE
Structure of P-AMINOPHENOL
METABOLITE ACTIVE -> PARENT
May be substrate for formation of AM-404
MINOR
Structure of ACETIMIDOQUINONE
METABOLITE TOXIC -> PARENT
Metabolite produced hepatic necrosis in man.
AMOUNT EXCRETED
URINE
Structure of ACETANILIDE
PARENT -> METABOLITE ACTIVE
Percent of dose excreted in urine as metabolite 60-80
URINE
Related Record Type Details
Structure of PHENOL, 4,4'-IMINOBIS-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYDROXYACETOPHENONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ACETANILIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIACETAMATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ACETAMINOPHEN DIMER
IMPURITY -> PARENT
Structure of 2'-HYDROXYACETOPHENONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 4-ACETYLAMINO-2-CHLOROPHENOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of O-HYDROXYACETANILIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of P-AMINOPHENOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of P-CHLOROACETANILIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of 4'-HYDROXYACETOPHENONE OXIME
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PARAPROPAMOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 4,4'-OXYBIS(ACETANILIDE)
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of ACETAMINOPHEN
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Tmax PHARMACOKINETIC
ORAL BIOAVAILABILITY PHARMACOKINETIC
MAXIMUM TOLERATED DOSE TOXICITY IV, LESS THAN 50 Kg

MAXIMUM TOLERATED DOSE TOXICITY
Tmax PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
RENAL CLEARANCE PHARMACOKINETIC
MAXIMUM TOLERATED DOSE TOXICITY
MAXIMUM TOLERATED DOSE TOXICITY
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