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Details

Stereochemistry ACHIRAL
Molecular Formula C22H30N6O4S
Molecular Weight 474.576
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SILDENAFIL

SMILES

CCCC1=NN(C)C2=C1N=C(NC2=O)C3=CC(=CC=C3OCC)S(=O)(=O)N4CCN(C)CC4

InChI

InChIKey=BNRNXUUZRGQAQC-UHFFFAOYSA-N
InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)

HIDE SMILES / InChI
Molecular Formula C22H30N6O4S
Molecular Weight 474.576
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:40:36 UTC 2023
Edited
by admin
on Fri Dec 15 15:40:36 UTC 2023
Record UNII
3M7OB98Y7H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SILDENAFIL
EMA EPAR   HSDB   INN   MI   VANDF   WHO-DD  
INN  
Official Name English
SILDENAFIL [VANDF]
Common Name English
SILDENAFIL RATIOPHARM
Brand Name English
APHRODIL
Brand Name English
HIP-0908
Code English
VIZARSIN
Brand Name English
PIPERAZINE, 1-((3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-4-ETHOXYPHENYL)SULFONYL)-4-METHYL-
Systematic Name English
SILDENAFIL [MI]
Common Name English
Sildenafil [WHO-DD]
Common Name English
HIP0908
Code English
SILDENAFIL [EMA EPAR]
Common Name English
SILDENAFIL ACTAVIS
Brand Name English
1-((3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-4-ETHOXYPHENYL)SULFONYL)-4-METHYLPIPERAZINE
Systematic Name English
SILDENAFIL [HSDB]
Common Name English
SILDENAFIL TEVA
Brand Name English
PATREX
Brand Name English
sildenafil [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2127
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS VIZARSIN (AUTHORIZED: ERECTILE DYSFUNCTION)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS REVATIO (AUTHORIZED: HYPERTENSION, PULMONARY)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
WHO-VATC QG04BE03
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS VIAGRA (AUTHORIZED: ERECTILE DYSFUNCTIONS)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
NDF-RT N0000175599
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
NDF-RT N0000020026
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS SILDENAFIL RATIOPHARM (AUTHORIZED: ERECTILE DYSFUNCTIONS)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS PATREX (WITHDRAWN: ERECTILE DYSFUNCTIONS)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
FDA ORPHAN DRUG 344211
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS SILDENAFIL ACTAVIS (AUTHORIZED: ERECTILE DYSFUNCTIONS)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EMA ASSESSMENT REPORTS SILDENAFIL TEVA (AUTHORIZED: ERECTILE DYSFUNCTIONS)
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
WHO-ATC G04BE03
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
EU-Orphan Drug EU/3/17/1885
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
LIVERTOX NBK548510
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
Code System Code Type Description
WIKIPEDIA
SILDENAFIL
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
EVMPD
SUB10517MIG
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
NCI_THESAURUS
C61940
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
DRUG CENTRAL
2441
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
FDA UNII
3M7OB98Y7H
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
CAS
139755-83-2
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
SMS_ID
100000089187
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
RXCUI
136411
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY RxNorm
ChEMBL
CHEMBL192
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
PUBCHEM
135398744
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
INN
7374
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
HSDB
7305
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
IUPHAR
4743
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
MESH
C101426
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
CHEBI
9139
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
DAILYMED
3M7OB98Y7H
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
EPA CompTox
DTXSID6023579
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
MERCK INDEX
m9898
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY Merck Index
LACTMED
Sildenafil
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
DRUG BANK
DB00203
Created by admin on Fri Dec 15 15:40:36 UTC 2023 , Edited by admin on Fri Dec 15 15:40:36 UTC 2023
PRIMARY
Related Record Type Details
MULTIDRUG RESISTANCE PROTEIN 1
TRANSPORTER -> INHIBITOR
OATP-8
TRANSPORTER -> INHIBITOR
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
OATP1B1
TRANSPORTER -> INHIBITOR
CYTOCHROME P450 3A5
METABOLIC ENZYME -> SUBSTRATE
Structure of SILDENAFIL CITRATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of DESMETHYLSILDENAFIL
METABOLITE ACTIVE -> PARENT
Structure of UK-150564
METABOLITE -> PARENT
Related Record Type Details
Structure of SILDENAFIL
ACTIVE MOIETY
NIH
NCATS
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