SILDENAFIL CITRATE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H30N6O4S.C6H8O7
Molecular Weight	666.7
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SILDENAFIL CITRATE

Structure Search

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCC1=NN(C)C2=C1N=C(NC2=O)C3=C(OCC)C=CC(=C3)S(=O)(=O)N4CCN(C)CC4

InChI

InChIKey=DEIYFTQMQPDXOT-UHFFFAOYSA-N

InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula	C6H8O7
Molecular Weight	192.1235
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C22H30N6O4S
Molecular Weight	474.576
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:44:31 UTC 2023` Edited by `admin` on `Fri Dec 15 15:44:31 UTC 2023`
Record UNII	BW9B0ZE037
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SILDENAFIL CITRATE

Official Name

English

SILDENAFIL CITRATE [USP MONOGRAPH]

Common Name

English

UK-92,480-10

Code

English

SILDENAFIL CITRATE [EP MONOGRAPH]

Common Name

English

NSC-744009

Code

English

SILDENAFIL CITRATE [VANDF]

Common Name

English

NSC-758669

Code

English

UK-92480-10

Code

English

SILDENAFIL CITRATE [MART.]

Common Name

English

SILDENAFIL CITRATE [USP-RS]

Common Name

English

SILDENAFIL CITRATE [MI]

Common Name

English

LIQREV

Brand Name

English

SILDENAFIL CITRATE [USAN]

Common Name

English

REVATIO

Brand Name

English

SILDENAFIL CITRATE [JAN]

Common Name

English

VIAGRA

Brand Name

English

1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate (1:1)

Systematic Name

English

SILDENAFIL (AS CITRATE)

Common Name

English

SILDENAFIL CITRATE [ORANGE BOOK]

Common Name

English

Sildenafil citrate [WHO-DD]

Common Name

English

PIPERAZINE, 1-((3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO(4,3-D)PYRIMIDIN-5-YL)-4-ETHOXYPHENYL)SULFONYL)-4-METHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)

Systematic Name

English

Classification Tree Code System Code

EMA ASSESSMENT REPORTS

VIAGRA (AUTHORIZED: ERECTILE DYSFUNCTIONS)

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

EU-Orphan Drug

EU/3/03/178

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

NCI_THESAURUS

C2127

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

Code System Code Type Description

DRUG BANK

DBSALT000347

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

EPA CompTox

DTXSID4046076

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

CHEBI

58987

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

ChEMBL

CHEMBL192

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

PUBCHEM

135413523

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

USAN

II-97

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

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RS_ITEM_NUM

1612561

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

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RXCUI

221161

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

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RxNorm

NCI_THESAURUS

C26670

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

MERCK INDEX

m9898

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

Merck Index

CAS

171599-83-0

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

SMS_ID

100000091090

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

FDA UNII

BW9B0ZE037

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

NSC

758669

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

NSC

744009

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

EVMPD

SUB04386MIG

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

DAILYMED

BW9B0ZE037

Created by admin on Fri Dec 15 15:44:31 UTC 2023 , Edited by admin on Fri Dec 15 15:44:31 UTC 2023

PRIMARY

Related Record Type Details


					BW9B0ZE037

SILDENAFIL CITRATE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

EP

Amount:


					BW9B0ZE037

SILDENAFIL CITRATE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:


					3M7OB98Y7H

PARENT -> SALT/SOLVATE

Amount:


					XF417D3PSL

ANHYDROUS CITRIC ACID

PARENT -> SALT/SOLVATE

Amount:

Related Record Type Details


					7GBN705NH1

IMIDAZOLE

IMPURITY -> PARENT

Comments:

any zone due to impurity E is not more intense than the principal zone in the chromatogram obtained with reference solution (b) (0.1 per cent)

Interaction Type:

CHROMATOGRAPHIC PURITY (TLC)

Qualification:

EP

Amount:


					9F7JAM9O4B

ISOBUTYL SILDENAFIL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					XVD449DO1O

DES(METHYLPIPERAZINYL) SILDENAFIL ACID

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					2TEH1FB1FX

O-DESETHYL SILDENAFIL

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					9F7JAM9O4B

ISOBUTYL SILDENAFIL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					380S4M4VB3

SILDENAFIL N-OXIDE

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP

Related Record Type Details


					3M7OB98Y7H

ACTIVE MOIETY

Amount: