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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H24N2O9.ClH
Molecular Weight 496.895
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXYTETRACYCLINE HYDROCHLORIDE

SMILES

Cl.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)C4=C(O)C=CC=C4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

InChIKey=UBDNTYUBJLXUNN-IFLJXUKPSA-N
InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1

HIDE SMILES / InChI
Molecular Formula C22H24N2O9
Molecular Weight 460.434
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:38 UTC 2023
Edited
by admin
on Fri Dec 15 15:00:38 UTC 2023
Record UNII
4U7K4N52ZM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OXYTETRACYCLINE HYDROCHLORIDE
EP   GREEN BOOK   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [MI]
Common Name English
TERRAMYCIN HYDROCHLORIDE
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [USP-RS]
Common Name English
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [EP MONOGRAPH]
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
OXYTETRACYCLINE HCL
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [GREEN BOOK]
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [VANDF]
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [MART.]
Common Name English
Oxytetracycline hydrochloride [WHO-DD]
Common Name English
OXY-KESSO-TETRA
Brand Name English
OXYTETRACYCLINE HYDROCHLORIDE [WHO-IP]
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [JAN]
Common Name English
TERRA-CORTRIL COMPONENT OXYTETRACYCLINE HYDROCHLORIDE
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
OXYTETRACYCLINE HYDROCHLORIDE COMPONENT OF TERRA-CORTRIL
Common Name English
OXYTETRACYCLINI HYDROCHLORIDUM [WHO-IP LATIN]
Common Name English
2-NAPHTHACENECARBOXAMIDE, 4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,6,10,12,12A-HEXAHYDROXY-6-METHYL-1,11-DIOXO-, MONOHYDROCHLORIDE, (4S-(4.ALPHA.,4A.ALPHA.,5.ALPHA.,5A.ALPHA.,6.BETA.,12A.ALPHA.))-
Common Name English
Classification Tree Code System Code
CFR 21 CFR 520.1660B
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
CFR 21 CFR 520.1660C
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
CFR 21 CFR 333.120
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
CFR 21 CFR 522.1662
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
EPA PESTICIDE CODE 6308
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
CFR 21 CFR 522.1662A
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
NCI_THESAURUS C1595
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
CFR 21 CFR 522.1662B
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID5021097
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
ALANWOOD
oxytetracycline hydrochloride
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
SMS_ID
100000092050
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
FDA UNII
4U7K4N52ZM
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
NCI_THESAURUS
C47649
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
OXYTETRACYCLINE HYDROCHLORIDE
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY Description: A yellow, crystalline powder; odourless. Solubility: Soluble in 2 parts of water and in 45 parts of ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Antibacterial drug. Storage: Oxytetracycline hydrochloride should be kept in a tightly closed container, protected from light. Labelling: The designation sterile Oxytetracycline hydrochloride indicates that the substance complies with the additionalrequirements for sterile Oxytetracycline hydrochloride and may be used for parenteral administration or for other sterile applications. Additional information: Oxytetracycline hydrochloride is hygroscopic. Even in the absence of light, it is gradually degraded onexposure to a humid atmosphere, the decomposition being faster at higher temperatures. Dissolved in water it becomes turbid onstanding owing to the separation of the base caused through partial hydrolysis of the hydrochloride. It deteriorates in solutions ofpH below 2, and is rapidly destroyed by alkali hydroxide solutions. Definition: Oxytetracycline hydrochloride contains not less than 870 International Units of Oxytetracycline per mg, calculated withreference to the anhydrous substance.
RS_ITEM_NUM
1491015
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
DAILYMED
4U7K4N52ZM
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
ECHA (EC/EINECS)
218-161-2
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
MERCK INDEX
m8345
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY Merck Index
ChEMBL
CHEMBL1517
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
EVMPD
SUB14740MIG
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
CAS
15000-39-2
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
NON-SPECIFIC STOICHIOMETRY
CAS
2058-46-0
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
DRUG BANK
DBSALT000645
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY
RXCUI
4780
Created by admin on Fri Dec 15 15:00:38 UTC 2023 , Edited by admin on Fri Dec 15 15:00:38 UTC 2023
PRIMARY RxNorm
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Structure of OXYTETRACYCLINE ANHYDROUS
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Structure of OXYTETRACYCLINE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
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Structure of OXYTETRACYCLINE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
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Structure of ANHYDROOXYTETRACYCLINE
IMPURITY -> PARENT
total of impurities D, E and F (eluting between the latter two): not more than the area of the peak due to impurity E in the chromatogram obtained with reference solution (g) (2.0 per cent)
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EP
Structure of 4-EPIOXYTETRACYCLINE
IMPURITY -> PARENT
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Structure of .ALPHA.-APO-OXYTETRACYCLINE
IMPURITY -> PARENT
total of impurities D, E and F (eluting between the latter two): not more than the area of the peak due to impurity E in the chromatogram obtained with reference solution (g) (2.0 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of .BETA.-APO-OXYTETRACYCLINE
IMPURITY -> PARENT
total of impurities D, E and F (eluting between the latter two): not more than the area of the peak due to impurity E in the chromatogram obtained with reference solution (g) (2.0 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-ACETYL-2-DECARBAMOYLOXYTETRACYCLINE
IMPURITY -> PARENT
not more than 4 times the area of the peak due to impurity A in the chromatogram obtained with reference solution
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of OXYTETRACYCLINE ANHYDROUS
ACTIVE MOIETY
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