FORMOTEROL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H24N2O4
Molecular Weight	344.4049
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FORMOTEROL

Structure Search

SMILES

COC1=CC=C(C[C@@H](C)NC[C@H](O)C2=CC=C(O)C(NC=O)=C2)C=C1

InChI

InChIKey=BPZSYCZIITTYBL-YJYMSZOUSA-N

InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C19H24N2O4
Molecular Weight	344.4049
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:38:31 UTC 2023` Edited by `admin` on `Fri Dec 15 16:38:31 UTC 2023`
Record UNII	5ZZ84GCW8B
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FORMOTEROL

Official Name

English

OXIS

Brand Name

English

FORMOTEROL [HSDB]

Common Name

English

FORMOTEROL [MI]

Common Name

English

EFORMOTEROL

Common Name

English

formoterol [INN]

Common Name

English

FORMOTEROL [VANDF]

Common Name

English

Formoterol [WHO-DD]

Common Name

English

FORMAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHYL)PHENYL)-

Systematic Name

English

rel-N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QR03AK08

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

NDF-RT

N0000175779

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

NCI_THESAURUS

C48149

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-VATC

QR03AK09

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AK08

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AK09

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

NDF-RT

N0000009922

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-VATC

QR03AC13

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AL07

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-VATC

QR03AK07

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AK11

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AC13

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-VATC

QR03AK11

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AL05

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

LIVERTOX

435

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AK07

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

WHO-ATC

R03AL09

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

Code System Code Type Description

FDA UNII

5ZZ84GCW8B

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

RXCUI

25255

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m5542

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

Merck Index

DRUG CENTRAL

1239

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

DRUG BANK

DB00983

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

IUPHAR

3465

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

ChEMBL

CHEMBL1256786

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

PUBCHEM

3083544

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

INN

4935

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

LACTMED

Formoterol

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

NCI_THESAURUS

C65754

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

HSDB

7287

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

SMS_ID

100000086897

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

CHEBI

5147

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

CAS

73573-87-2

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

DAILYMED

5ZZ84GCW8B

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

EVMPD

SUB07788MIG

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

WIKIPEDIA

FORMOTEROL

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

EPA CompTox

DTXSID1023077

Created by admin on Fri Dec 15 16:38:31 UTC 2023 , Edited by admin on Fri Dec 15 16:38:31 UTC 2023

PRIMARY

Related Record Type Details


					P3T5QA5J9N

FORMOTEROL FUMARATE ANHYDROUS

SALT/SOLVATE -> PARENT

Amount:


					081I12ZA58

CYTOCHROME P450 2C19

METABOLIC ENZYME -> SUBSTRATE


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> SUBSTRATE


					4A4MK4KIB5

BETA-1 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Comments:

Measurement of cAMP production in CHO cells stably expressing comparable levels of the human

Qualification:

EC50

Amount:


					246D9TQ2XG

CYTOCHROME P450 2A6

METABOLIC ENZYME -> SUBSTRATE


					VZX139UJO5

BETA-2 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE


					PG244BS39U

BETA-3 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Comments:

Measurement of cAMP production in HEK-293 cells stably expressing comparable levels of the human

Qualification:

EC50

Amount:


					VZX139UJO5

BETA-2 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Comments:

Measurement of cAMP production in CHO cells stably expressing comparable levels of the human

Qualification:

EC50

Amount:


					5ZZ84GCW8B

EXCRETED UNCHANGED

Interaction Type:

AMOUNT EXCRETED

Qualification:

URINE

Amount:


					W34SHF8J2K

FORMOTEROL FUMARATE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					5D3XQB6YM9

2-AMINO-4-((1R)-1-HYDROXY-2-(((1R)-2-(4-METHOXYPHENYL)-1-METHYL-ETHYL)AMINO)ETHYL)PHENOL

METABOLITE -> PARENT


					M6VSY7YT2D

N-(2-HYDROXY-5-((1R)-1-HYDROXY-2-(((1R)-2-(4-HYDROXYPHENYL)-1-METHYL-ETHYL)AMINO)ETHYL)PHENYL)FORMAMIDE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Qualification:

FECAL

Related Record Type Details


					5ZZ84GCW8B

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC				INHALED ADMINISTRATION

Biological Half-life	PHARMACOKINETIC